What dose of reta are you at?

muhvugga said:
So that’s like nearly 10 wks, for an average loss of nearly 4lbs a week. At that rate I think you’re likely to be losing muscle weight as well.
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Yeah, that's a bit to fast. I'm about 1-2lbs/week on 8mg. Due for pin #5 on Friday. We'll likely stay here if possible. I have like 5-10lbs to go. Then I'll figure something out for maintenance.
 
1.5 months in and at 4 every five days. I've lost 4 pounds. I'm a very slow at losing weight. Probably because I'm very short. It's just harder for me.
 
BigRed1 said:
Good luck

This is what I said week 1 because it worked so good out of the gate, but on weeks 2-3 the appetite suppression dropped pretty heavy for me.


I'm going up to 2mg now in a few days
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Sounds like some people supplement with cagri for the hunger suppression with both tirz or Reta

Something to consider if you need more help
 
I lost like 10 pounds and a pants size or two in my first month of Tirz, but that was mostly in the first two weeks. I bounced around after that, never really going lower, but definitely less body fat overall I’d say.

I’ve switched to Reta now and I’m doing 1mg split doses, 2mg a week. I just took my second dose of the week today.

I will say I woke up after the first night on 1mg and had an anxiety attack in the morning. I could feel my heart rate being higher than normal and not going down… which feels like the start of an anxiety attack and thus ended up becoming one, lol.

I can’t really feel the Reta as much as the Tirz besides that, though my energy seems better so far. I do feel like I’m easier to sweat though.
 
To my fellow nerds out there, here is some information about the phase 3 trials of Reta. Great results.

They started participants at 2mg weekly. Then monthly titrated up to 4mg, 9 mg, then 12mg. Obviously high doses are not meant for everyone but 8mg seemed to be the sweet spot for some things. If anyone follows Dr. Alex Tatem, he put out a great video about it also.
https://investor.lilly.com/news-rel...st-retatrutide-delivered-powerful-weight-loss
 
Just titrated to 7mg this morning (week 12). Week 1-4 2mg. Week 5-8 4mg. Week 9-11 5 mg. 5’10 male starting weight 286 Feb 15th. Started Reta March 26th at 266 lbs. weighed in this morning at 238lbs. According to my run star scale I’m down 37.2 lbs body fat and up 9.5 lbs lean body mass since starting Reta at the end of March! I’m at 1600 calories per day, 200g protein. Lift 4 days a week and cardio 2-3 days a week.
 
Retarage said:
Just titrated to 7mg this morning (week 12). Week 1-4 2mg. Week 5-8 4mg. Week 9-11 5 mg. 5’10 male starting weight 286 Feb 15th. Started Reta March 26th at 266 lbs. weighed in this morning at 238lbs. According to my run star scale I’m down 37.2 lbs body fat and up 9.5 lbs lean body mass since starting Reta at the end of March! I’m at 1600 calories per day, 200g protein. Lift 4 days a week and cardio 2-3 days a week.
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That’s amazing, great job!
 
Valkyrieshadow said:
To my fellow nerds out there, here is some information about the phase 3 trials of Reta. Great results.

They started participants at 2mg weekly. Then monthly titrated up to 4mg, 9 mg, then 12mg. Obviously high doses are not meant for everyone but 8mg seemed to be the sweet spot for some things. If anyone follows Dr. Alex Tatem, he put out a great video about it also.
https://investor.lilly.com/news-rel...st-retatrutide-delivered-powerful-weight-loss
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Sorry, but that's a misinterpretation of the details of that study.

Nobody in the TRIUMPH-1 study went from 4 mg to 9 mg. There is also nobody taking the 8mg dose you mention at any time. There was a group of participants who titrated to a maximum of 4mg, a group of participants who titrated to a maximum of 9mg, and a group of participants who titrated to a maximum of 12mg, plus a placebo group (intentionally ignoring the 24 week trial extension for a minute). The titration steps were 2mg, 4mg, 6mg, 9mg, and 12mg.
 
My guess is that just like the current ongoing EL trial of tirz testing the increased dosages (20/25mg), Reta will eventually also be tested for 12+ mg dosage.
 
I’m back down to 5mg, went to 10mg and felt so lethargic. I added in 500mcg of semiglutide to help with appetite surpression with the Reta, but about to drop it due to some weird side effects (jaw clinching)
 
Driftroot said:
Wife and I started 6 weeks ago; she started with Tirz at 2.5/1wk. I started with Reta at 2.5mg/wk. She has lost about 18lbs and I have dropped 28lbs.

I definitely regret not starting at .5 and titrating up. I allowed my emotions to get the best of me when I made the choice to start on the larger scale of doses. It’s taken my body some time to recover from a 2.5mg start on Reta.
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You guys dump weight faster than we do anyway... 🙃
 
janedoe said:
Maintenance with Reta since 5/25. Intially on Cagri stack in Reta Maintenance, but dropped the Cagri 11/25 due to inadvertently loosing 15lbs more than I wanted past my goal weight. Still on 3mg 1x weekly. Weight stable.
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That seems like the cagri really helped.
 
Johnny D said:
Is 1mg weekly Reta a good starting dosage, or should I start with 1/2 mg (500 mcg)??
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I really think you need to take your personal history into account when answering this question. If your system is acclimated to GLP1, you can start at a higher dose. If you've never taken a GLP1, you can't really know if you're more or less sensitive to it. I'd recommend erring on the side of caution in that case, bc if you OD at first you can get very uncomfortable, and there's nothing for it but waiting it out . . .
 
Builderman said:
Why such a low dose to start? Are you seeing benefits with that low of a dose?
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I started reta at .5 because I was sensitive to tirz. Gradually titrated up to 2mg with no sides. Some people get results at .5, some people have bad sides. It makes sense to start low and avoid those, unless you already know you don't respond to GLP1 until the dose is a lot higher.

Some people are skeptical about low doses, even though there's a ton of evidence that some people do much better on those. It doesn't show up on RCT because low doses weren't tested, I doubt Lilly and Novo are super curious about how little medication can be sufficient as that would cut into their profits. Cumulative individual experiences show the range of "effective" can be pretty wide.
 
muhvugga said:
Story of a slow responder here…

My starting weight is 285lbs, with a BMI of about 36. I was at 300 at my heaviest in Oct-Nov of last year when I started OMAD fasting and getting more active, which got me down to my starting weight by Jan.

For the past 4 months on OMAD I’ve completely stalled out - no change at all in weight even with occasional 36 hr fasts and increased walking.

So I started reta 2 weeks ago and also started really ramping up my activity (rowing machine Mon-Fri week, and adding kettlebell workouts Mon, Wed, Fri))

Week 1: I took an initial 1mg shot waited 4 days to check for any immediate sides (no issues) and took another 1mg.

Week 2: I’m now doing 2mg every 7 days as my plan for the rest of the first month.

The scale has hardly moved (currently 284 thanks to lees food and more intense workouts). I do feel more immediately sated from OMAD eating time than before, and do occasionally have to keep hydrated, but otherwise I hardly notice any side effects.

I’m now just focusing on getting really into being active and (not so patiently) hoping to see some actual reta-results at the end of month 1 in a few weeks. Even if it’s still slow the mild appetite help and motivation to not lose muscle and bone while on reta really helps motivate a lifestyle change that I now want to upkeep.
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I wish your post could be pinned to the top of the ones insisting CICO is the only variable, and that only if you consume less and move more can you lose. If that were true, you'd have lost weight when you cut back on eating and boosted movement.

That may be true for some, but others have complicated metabolic systems and they don't work that way lol. Thank goodness we have these drugs that help normalize our systems and allow us to lose weight doing the same things that didn't work without them.
 
2 - 3 mg every 7 days for about a year, with some month long breaks in between. went from 160 to 120 with weightlifting
 
Camlbacker said:
I am in my fourth month on Reta, and currently doing 3.5 1x per week. 4-4.5 is probably closer to ideal though. I'm at the end of a vial, and the last shot will be 4. I'll move to 4.5 if that doesn't seem to be adequate. I took 5 a couple of weeks ago, and that was too much. There is definitely a learning curve to this stuff. I went from dosing every other day to once a week in about a two week period, and really had to rethink and rework EVERYTHING.
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10 mg weekly but I was on a 2.4 of wegovy before switching to reta.
 
AngieHolmes said:
I wish your post could be pinned to the top of the ones insisting CICO is the only variable, and that only if you consume less and move more can you lose. If that were true, you'd have lost weight when you cut back on eating and boosted movement.
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100% agree - it’s seriously pretty tiring to encounter that. Getting interrogated and having to exhaustively prove you’re putting in the work before you can get past the CICO platitudes to gain some real insights and advice gets old fast.

Reddit is just the absolute worst in that regard. I’m pretty grateful this community exists as an alternative.

Based on advice here I started looking into Thyroid health factors, my supplements, and some of my previous bloodwork, and doing more research - and it started to help me really understand how big of a hole I was in with the combo of age, obesity and a years of a sedentary lifestyle.

I’m extremely happy to say that it’s all paying off and the hard workouts are now accelerating the weight loss on top of the reta (now down 15lbs and on my 4th dose at 6mg). It’s to the point where I’m now monitoring my average weight loss per week to make sure it isn’t moving way too fast.
 
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Builderman said:
Why such a low dose to start? Are you seeing benefits with that low of a dose?
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I chose to start low because I wanted to see how my body would react to that dose, and I definitely did feel side effects at 1mg. If I would’ve started at 2mg I know I would’ve died😭 I’m also not over weight and didn’t want to over do it and my goal is mainly to body recomp. I’ve lost about 5-6 lbs which may not be a lot but I definitely am looking more toned and leaner so I’d say I am seeing benefits 😁
 
Lmao123 said:
I chose to start low because I wanted to see how my body would react to that dose, and I definitely did feel side effects at 1mg. If I would’ve started at 2mg I know I would’ve died😭 I’m also not over weight and didn’t want to over do it and my goal is mainly to body recomp. I’ve lost about 5-6 lbs which may not be a lot but I definitely am looking more toned and leaner so I’d say I am seeing benefits 😁
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Makes sense. I also started at 1mg but am about 100 pounds overweight and personally should have started higher.
 
this is what im at currently. Hoping to stay at 1.5mg for another couple of weeks.
Currently down 4.1kg.

week 1: 1mg
week 2: 1mg
week 3 1.5mg
week 4: 1.5mg
 
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