What Percentage of Body Weight Have You Lost?

[m100568]

30%. Started August 2025 at 225, now I'm at 155 and switched to maintenance. My surgeon estimates he will remove 10lbs of skin. That will bump it up to 35% loss.

Wow, congratulations! Yeah, the ecstasy of losing weight is tempered by the reality of what maintenance looks like. I'm almost at maintenance. I have a plan, but it is subject to change. I'm down 98lbs but I don't think I will have skin removal. I don't have folds of skin, but the crinkled orange peel effect sure doesn't look good. Whatever. I'm doing this for health, not vanity. Not having high blood pressure, diabetes, fatty liver, etc., etc., is much better than the alternative. I'm grateful for what I have achieved. Oh, and by the way, I am now down 40%.

 

[tangoecho311]

Oh, and by the way, I am now down 40%.

Congrats! That's amazing! I don't *want* surgery but after I carried twins then lost 130lbs from my highest pregnancy weight... I have an unfortunate apron of skin that's got to go. And if we're doing surgery I'm going all out on a 360 lift.

 

[SDglp188]

I was looking at the mouse study on Retatrutide and cancer. https://www.nature.com/articles/s44324-025-00054-5 The cancer implications are very interesting on its own, but that is not the purpose of this post. The other thing that caught my eye in the study is that the mice lost 40% to 41% of body weight and stabilized there. We have the Phase II data of 24.2%, but people were still losing weight after 48 weeks. There is no published data on when it plateaus. EL has extended the studies, so it looks like they are trying to find that out.

I have been stacking Tirz and Reta for 8 1/2 months. I have lost 35% of my body weight and I am still losing. I would like to get down to 40% to reach my ideal weight. My question is for people on maintenance or close to maintenance; what percentage of your body weight have you lost? Has anyone hit 40%, or more?

I have lost 43% of my body weight. I have been maintaining for over a year now. Tirz 100% of the time. I have stacked Sema and Cagri. A few months on one then a few months on the other. Just to switch things up.

 

[Morbius]

6.9% (1.7 lb/week) in 8 weeks with 2 mg reta weekly. My goal is 15-17%. I have no idea what I will do for maintenance, though.

I will stick with this low dose until it stops working. I guess I could be losing weight more quickly, but I am having zero side effects and 2 mg reta is cheap. I eat and drink whatever I want, I just want less. This is as easy as falling off a log.

 

[StonePny]

Since starting five weeks ago: 7 percent (3.4 pounds per week, 17 pounds total: 241 pounds to 224).

Dosing: Went up 2.5 mg weekly to 10 mg of tirz, as suggested by my internist.

17 lbs in 5 weeks--that's so great! I know this is older, but still. Where are you at now?

 

[nonyabizznez]

30%. Started August 2025 at 225, now I'm at 155

That's awesome and welcome back from the future! 🤣 (Sorry... low fruit)

 

[tangoecho311]

That's awesome and welcome back from the future! 🤣 (Sorry... low fruit)

Im not even going to fix it. 🤣

 

[haydeecm]

33% at 11 months in with tirzepatide. I thought I was done but now I’m thinking of going down 6 more pounds.

 

[Calm Logic]

17 lbs in 5 weeks--that's so great! I know this is older, but still. Where are you at now?

Relatively stalled. About a pound a week, on average.

 

[Iamnew2this]

Relatively stalled. About a pound a week, on average.

Do you think that's a stall? I think a pound a week isn't bad.

 

[Calm Logic]

No. But I was hoping to still lose at least 2 pounds a week on average. So I recently switched to dosing tirz every five days instead of weekly to see if that helps.

 

[Iamnew2this]

No. But I was hoping to still lose at least 2 pounds a week on average. So I recently switched to dosing tirz every five days instead of weekly to see if that helps.

That's a great idea and it should help. It's helped me before. Good luck to you!

 

[Morbius]

How our perspectives change! An easy pound a week would have been awesome not so long ago.

I had a cabin getaway long weekend where I ate and drank too much, I still lost 0.6 lbs over the week. I felt ungrateful for being a little disappointed, haha.

 

[jestintime]

40% down and counting in 9.5mos! Aiming for around 44% down and still making steady progress, so expect to hit it in a month or so.

 

[marieacadica]

I was looking at the mouse study on Retatrutide and cancer. https://www.nature.com/articles/s44324-025-00054-5 The cancer implications are very interesting on its own, but that is not the purpose of this post. The other thing that caught my eye in the study is that the mice lost 40% to 41% of body weight and stabilized there. We have the Phase II data of 24.2%, but people were still losing weight after 48 weeks. There is no published data on when it plateaus. EL has extended the studies, so it looks like they are trying to find that out.

I have been stacking Tirz and Reta for 8 1/2 months. I have lost 35% of my body weight and I am still losing. I would like to get down to 40% to reach my ideal weight. My question is for people on maintenance or close to maintenance; what percentage of your body weight have you lost? Has anyone hit 40%, or more?

That is an awesome loss!! I started in October 2024 on Tirz. I haven't gone above 5mg as of yet. Losing approx 1.5 lbs a week. Was thinking of stacking Reta for the extra energy that it supposedly gives. Did you start with Tirz & then add Reta? Or did you just start them both together? If you started with Tirz & then added Reta, did you notice more/faster weight loss? In your experience what did Reta do that Tirz didn't? What are your dosages on your Tirz & Reta stack? I am so sorry for all of the questions; I have been reading so much & even though I have been on Tirz for awhile, I just found this forum - - and it is awesome to hear about others journeys!!

 

[RighteousCrone]

Starting weight 234# on 4/1/24, Current weight 164# on 5/22/25; so down 70# - 29.91% body weight. I have been on Tirz throughout. Lost most from April '24 thru Oct '24 staying at 5mg dose. I plateaued and weight hovered around 175 for months while at 7.5 dose. I just started losing again this month (May '25) at am at 164#. I was fine with maintaining - but I'm more active in the garden - so physical movement and Spring weather has boosted my energy!

 

[Iamnew2this]

Starting weight 234# on 4/1/24, Current weight 164# on 5/22/25; so down 70# - 29.91% body weight. I have been on Tirz throughout. Lost most from April '24 thru Oct '24 staying at 5mg dose. I plateaued and weight hovered around 175 for months while at 7.5 dose. I just started losing again this month (May '25) at am at 164#. I was fine with maintaining - but I'm more active in the garden - so physical movement and Spring weather has boosted my energy!

Congratulations ❤️