When using peptides. Does everyone just...

[JoonyO]

fill up a dose of whatever from the fridge and pin right away...or let it sit out for a pre-determined amount of time?
Seriously.

 

[Peotidethrowaway]

Usually if you can’t find anyone talking about doing something like prefilling their dose and waiting, it means no one does that 😀

 

[MsGizmo]

fill up a dose of whatever from the fridge and pin right away...or let it sit out for a pre-determined amount of time?
Seriously.

Not really sure the point of what you are asking so I will give my entire process from start to finish.

I have 10mg vials of semaglutide. I store them in the freezer.
I take out a vial to warm up for 10 minutes or so.
I reconstitute with 2ml of BAC water.
I transfer the contents of the vial into a injection pen cartridge.
I put the cartridge in the pen. (photo of pen assembly below)
Remove excess air from the cartridge.
To do this I waste an needle and dial in "doses" with the pen and hit the button until the air is all gone. I'm sure you could find a youtube video of the process if you are curious.



My dose of sema is 1 mg per week.
I have used a peptide calculator and it tells me that I need 20 units.
On my injection day I attach a needle, set the dial to 20
I jab myself in a squishy spot and push the button.
Remove the needle and dispose of it safely.
When my pen is not in use I keep in it a pencil case in the fridge. I do not pay any attention to temperatures.

There are two things here that I admit are problematic.
#1 - I don't filter. Doing this increases the level of risk I am taking.
#2 - I keep and use reconstituted vials for more than 28 days.

I might start filtering at some point. But as it is now I haven't looked into the process and I don't have the supplies. I will continue to use cartridges for longer periods of time. I don't personally believe that they expire that fast. But that is solely my own opinion with no medical facts to back me up. If it ever becomes a problem then I will only have myself to blame.

 

[vewdew34]

I never wait, take out the fridge and pin.

 

[jordekorn]

When I take my Dupixant, I let it sit out, it’s a lot of liquid, I let it sit for hours sometimes. When I do peptides I fill, clean up the wrappers, paper towels and alcohol pads, then inject.
Dupixant is safe sitting out for days though(14 days before it’s bad), not sure about peptides.

 

[holiday]

I don't wait on purpose, but seems like I might have the vial out for around 5 mins or so before I use it.

 

[aquis]

I also take it out of the fridge and pin. I go through my routine and don't rush, but no dedicated wait time.

 

[cheaperseeker]

I pin straight from the fridge.

 

[Morbius]

The amount drawn into the syringe is so tiny it's going to be close to room temperature by the time you inject it.

LET'S DO THE MATH

Well, let's ask an AI to do the math, because I am lazy and I am not going to look anything up. I did measure a 1 cc insulin syringe at 2.5 g though, and I think it's made from polypropylene. So if we assume the syringe is at 68F and the liquid in the vial is at 40F... When the liquid comes to equilibrium with the warmer syringe, it will rise to about 62F.

That's obviously a highly simplified model but ...

Just inject it.

I don't see the point of waiting, what could be the benefit?

 

[desinr-gal]

I dont wait. I have never had a problem injecting a cold substance, and In an effort to extend the life of my peps, I complete the process and get them back in fridge asap. Also I am using pens, so the rest is sitting in the pen..

 

[JoonyO]

I asked because I've had some really crappy nights when taking tesa. Terrible sleep/insomnia. Only on .4mg and ONLY happened on the first pin of a new vial. But EACH new vial was the same crap night. No issues after initial pin. I was a bit concerned so called and the pa who I got the stuff from suggested that I let it sit out for 20 minutes before using. I've since went to 1mg a couple of weeks ago no issues-no new vial YET either so there's that.
Anyway I was recommended for the tesa because I initially thought trt might explain a couple issues ( one of them lousy sleep ) however blood work came back at 860 so she couldn't prescribe test. She laughed a little when she said it ( I'm coming up fast on 70 so it is kinda funny ) and obviously I don't NEED it though I still kinda wanna try it. 😬
Switched to Reta from sema about 3 weeks ago. Started Sema 7/11. My first venture with peptides and it was really just to try to lose "stubborn belly fat". I was mostly carnivore for over a year but hit plateaus for 6-8 months and grew frustrated with the stall. Have dropped 20lbs ( CW 179lbs ) or so since July so I'm satisfied, mostly, with this. Pinning 2mg reta ( .5 to start and then Img for a week and am at 2mg now-starting yesterday and then Thursday and intend on 3mg Mon/Thur next week. Unless I have side-effects people talk about.
So that's why I asked. Tonight I will go straight from the fridge.
Thanks for all the thoughts.