Will Cagri-Sema Be The New Hotness?

[astroman]

Less fatigue than sema or tirz, and I can actually enjoy food on it. We’ll see what happens though, the heart rate increase isn’t ideal. Watching it closely, if it doesn’t go down I’ll probably just switch back to tirz.

Out of curiosity, how high is your HR?

 

[exploitedworkerbee]

Out of curiosity, how high is your HR?

At rest it’s mid-90s at the moment, which isn’t the end of the world, what bugs me is that after working out it takes forever to come back down. So I’ll be sitting there for like 30 minutes with a 135 hr

 

[astroman]

At rest it’s mid-90s at the moment, which isn’t the end of the world, what bugs me is that after working out it takes forever to come back down. So I’ll be sitting there for like 30 minutes with a 135 hr

Holy… that’s high, my friend.

 

[amynurse]

At rest it’s mid-90s at the moment, which isn’t the end of the world, what bugs me is that after working out it takes forever to come back down. So I’ll be sitting there for like 30 minutes with a 135 hr

This is why my RS can't ever try reta. RS has hyperadrenergic POTS....in TLDR, that means RS's HR and BP spike when going from seated/lying to standing. It eventually evens out to normal, but it's not fun. Taking a hot shower=130-150HR. RS will likely microdose cagrisema or cagritirz once at goal weight. Or maybe some of the others in the pipeline will be an option by then. 🤷‍♀️

 

[SmokeySquid]

Cagri-tirz is stall-breaking magic in my experience. Adding cagri broke an 8 month stall, then coasted to goal weight. Downside is pretty significant fatigue but it was worth it.

Man combine cagri and some benadryl and I can just sleep till the weight is gone 🤣

In all seriousness, did you feel any fatigue on triz? Being fatigued is the only real side effect my RS has experienced on triz and while not debilitating, it definitely sucks.

Edit: I see you had fatigue on triz in a later post. My bad.

 

[Tomes]

So tirz>sema.
Cagri-sema> Tirz.

This is neither supported by the data (tirz - 21% weight loss at 36 weeks; cagrisema - 15% weight loss at 32 weeks), nor would it be true for every individual. I think I would cease to function if I took cagrisema, given they are both extremely potent on delaying gastric emptying. 100mcg of cagri is enough for me to feel like absolute crap every time I eat for the first couple days.

 

[astroman]

This is why my RS can't ever try reta. RS has hyperadrenergic POTS....in TLDR, that means RS's HR and BP spike when going from seated/lying to standing. It eventually evens out to normal, but it's not fun. Taking a hot shower=130-150HR. RS will likely microdose cagrisema or cagritirz once at goal weight. Or maybe some of the others in the pipeline will be an option by then. 🤷‍♀️

Pots is a b****. I just got tested for it and fortunately came back normal, but I swear. Couldn’t be the severe anxiety or 190/110 BP 😂

 

[amynurse]

Pots is a b****. I just got tested for it and fortunately came back normal, but I swear. Couldn’t be the severe anxiety or 190/110 BP 😂

That's really high, for not having POTS! Are you on statins or anything for it? My RS has the wonderful trifecta that is Ehlers Danlos/POTS/MCAS. Yay, I guess 🎉🤣

 

[astroman]

That's really high, for not having POTS! Are you on statins or anything for it? My RS has the wonderful trifecta that is Ehlers Danlos/POTS/MCAS. Yay, I guess 🎉🤣

Just Nebivolol and Zoloft 😂 you’ve got it all covered!

 

[moonpies4misfits]

I’ve recently heard of CagriSema (not named by yours truly). I would like to see some studies in that combo in comparison to just T or the CT combo.

I actually tried to get in on one of those research studies before I found the wonderful world of Peptides, but they were full by the time I signed up.

 

[Laxfinity]

Cagri-tirz is stall-breaking magic in my experience. Adding cagri broke an 8 month stall, then coasted to goal weight. Downside is pretty significant fatigue but it was worth it.

Can I ask what dose you started on with Cagri? I have stalled huge with Oz. I have added tirz mid week and nothing...

 

[Laxfinity]

This is neither supported by the data (tirz - 21% weight loss at 36 weeks; cagrisema - 15% weight loss at 32 weeks), nor would it be true for every individual. I think I would cease to function if I took cagrisema, given they are both extremely potent on delaying gastric emptying. 100mcg of cagri is enough for me to feel like absolute crap every time I eat for the first couple days.

Is 100mcg your starting dose? Looking to do this now. Thanks.

 

[exploitedworkerbee]

Can I ask what dose you started on with Cagri? I have stalled huge with Oz. I have added tirz mid week and nothing...

Started at .5mg, worked my way up to 2.5mg.

 

[moonpies4misfits]

Can I ask what dose you started on with Cagri? I have stalled huge with Oz. I have added tirz mid week and nothing...

What's your tirz dose?

 

[Glp1judd]

You’ve just now made me realize how low the dosage is. My RS is only on week 2 of T and have found the next day and two days after shot day is notably higher in weight drops. I wonder if it’s similar across all GLP’s

Interesting. I find my noticable drops also happen day 2 after injection. I thought just water, but it’s pretty consistent week after week, month after month. Only a pound or two a week, but pretty steady. Down almost 60 so far.

 

[Tessie]

Pots is a b****. I just got tested for it and fortunately came back normal, but I swear. Couldn’t be the severe anxiety or 190/110 BP 😂

My daughter has POTS symptoms. It did not show up in table test, Dr said sometimes the test does not work, she’s had issues for years.

 

[Laxfinity]

What's your tirz dose?

I am up to 5. I do 1.5mg Oz on Sunday and 5mg of tirz Weds.

 

[PopTart]

I promise I’m not being pessimistic, but 8 months?! You have so much more patience than I

He was waiting on an order from QSC so the 8 months went by pretty quickly.