desinr-gal
GLP-1 Enthusiast
After hearing Peter Magic say dont use them beyond 4wks, I tossed my still half full vial of Tirz that was well beyond one month in use. I am regretting buying the kits of T30s.. because I am still on a low dose..
Your SSA Experience…
- Thread starter Emmwhyyy
- Start date
byefatlicia
GLP-1 Enthusiast
Mail them to me and I'll make sure they get disposed of "properly" 😂
cheaperseeker
GLP-1 Apprentice
Same! If you happen to live within a few hours of SE Iowa, I'll come and pick them up!
Seriously though, when I worked in long-term care, we only ever threw out medication vials after 28 days if we knew state would be coming for an inspection soon (Not great, I know. Don't get me started on how effed up our medical system is.). There was never an issue with ISRs or ineffective meds. This is not medical advice, just my experience.
Calm Logic
GLP-1 Specialist
To reduce punctures, you can split into multiple vials after recon, or switch to using pens.
cheaperseeker
GLP-1 Apprentice
This! I just switched to pens and they have made my life so much easier.
desinr-gal
GLP-1 Enthusiast
I was given two reconstituted vials from a Compounding pharmacy. I used the first over 2-3 months and had been on the second for over a month. So between the original compounding date in april and the first usage date (I dose every other day, so many more cap pokes) I got worried. Though I have never even had an ISR. I didnt want to push my luck. I am not throwing away the t30 vials haha. But Next round I will get the lower dosage ones. I just read through BAC water studies and I feel more confident about BAC.
desinr-gal
GLP-1 Enthusiast
I am still waiting for my pens..They were shipped by slow boat to Hawaii via USPS by error since priority mail had been paid for. aaargghh.
However. Pen cart caps are still perforated each use, just like the vials. And if you leave the needles on, you are exposing your peptide to outside air that whole time.
Calm Logic
GLP-1 Specialist
Yes, but.... "The surface of the vial's rubber stopper is much larger and more exposed than the tiny septum of a pen cartridge" (Google Gemini). And a reusable pen is a more closed system in general, e.g. not requiring air to be inserted.
The worst experience I had with a vial was a vial of B-12. I punctured it at least eight times already, but I somehow made a semi-leaky hole with a small 31-g needle. So I guess I hit the same spot at least twice or did something else to core the vial. (For a thick needle, like a 18-g fill needle, it is best to use a 45-degree insertion angle into the vial, with the bevel side up.)
Last edited:
desinr-gal
GLP-1 Enthusiast
Yikes. The coring potential is real, There is an NIH study I read on that. You could argue that since the cart cap gets repeatedly punctured in the same spot, the risk may be greater. whereas the larger vial cap area means less likelihood of hitting the same spot and coring it. I bought the older V1 type pens so I can keep it fully closed. I've never used them and Im looking forward to it.
Peter Magic didn't (at least in the Rory interview recently posted) say that.
He said, off the cuff, that risk of injection site reaction might increase with potential microbial growth. He was probably referring to vials reconned with saline or sterile water (which is what's available in the rest of the world) rather than bacteriostatic water (which includes benzyl alcohol to suppress microbial growth).
He mentioned 2-4 weeks as his ideal usage period.
I'm sticking with 3 months, and considering refreezing weekly bc why not.
Calm Logic
GLP-1 Specialist
desinr-gal
GLP-1 Enthusiast
I hope Gemini is correct. 🙂
Jack brown
GLP-1 Apprentice
If Peter Magic is comfortable with 4 weeks on STERILE water then I think 8 weeks with bacteriostatic water should be ok...
byefatlicia
GLP-1 Enthusiast
Go with your gut reaction...
randompersonrandom
GLP-1 Enthusiast
Dangit, I JUST posted pen-angst in a whole separate thread a few hours ago, because I couldn't find any conversations about whether or not a pen could make a high-dose vial work better for someone on a low dose....and now HERE'S the conversation I've been hoping to eavesdrop on, in the damn SSA thread! I can't with all y'all. 😂
Amen to that love my pens, time savers and easy.
You telling me you would reuse a needle?
randompersonrandom
GLP-1 Enthusiast
I think she means you swap the needle after using and store with a fresh, capped needle on it, which some people do but most people agree is a bad idea.
desinr-gal
GLP-1 Enthusiast
No. Sorry I wasn't clear. Some users add the new needle ahead of time, as was suggested by the pen seller, for convenience.
desinr-gal
GLP-1 Enthusiast
good idea!
desinr-gal
GLP-1 Enthusiast
I watched it and I'm pretty sure he did say the safest thing is to toss after 4 wks regardless of type of water, because bacteria can be growing inside (I am paraphrasing) That's why you should only get smallest dose vials that will be used up in that time frame. Now whether the risk is isr vs a systemic infection, is something I dont want to get wrong.
I had read somewhere that its not good to refreeze??
Calm Logic
GLP-1 Specialist
The only reason I haven't bought from SSA is their MOQ. But there is a group on Discord that does collective buying from SSA to avoid the MOQ issue.
I think so. The few papers on coring of the septum of insulin pen cartridges are mostly in Japanese or bad English, and they are using microscopic imaging.
In an older post (not in this SSA thread, haha), it was mentioned that some new, cheap vials from Amazon leak anyway:
So I bought Hospira-brand empty vials after reading that.
I haven't seen anything yet about leaking pen cartridges. Is that a thing? I sometimes use disposable pens of liraglutide from India, and they never leak.
I think so. The few papers on coring of the septum of insulin pen cartridges are mostly in Japanese or bad English, and they are using microscopic imaging.
In an older post (not in this SSA thread, haha), it was mentioned that some new, cheap vials from Amazon leak anyway:
So I bought Hospira-brand empty vials after reading that.
I haven't seen anything yet about leaking pen cartridges. Is that a thing? I sometimes use disposable pens of liraglutide from India, and they never leak.
Last edited:
RocketGotRobbed
GLP-1 Apprentice
Ordered Aug 2. Received today, August 29. Did not provide tracking number for over a week. Asked everyday when iit would be avaialble and was told each time that it would be "tomorrow." Finally received tracking, it was a Fedex number that was no good until the package was picked up in the states. Did not even get picked up in China until 8/13 even though it had been paid for 11 days. Communication was bad from the start. But, everything arrived. It appears to be in good order.
latviantower
GLP-1 Enthusiast
Update: Success! Orders complete and confirmed on the 15th, FedEx label created on the 20th (peps), Bmurfs Express order (tabs) arrived US on the 25th and sat at O’Hare for a bit, delivered on the 30th. Peps arrived JFK on the 28th, delivered on the 31st. So 15/16 days total, with a big promotion in the middle of that time, plus just ahead of the de minimus tariffs kicking in.
Until the de minimus situation is clarified (hurry up you activist judges - strike it all down!), think I’ll use US warehouse for next order.
Soccerdude
GLP-1 Novice
How many have you frozen vials? i bought t60 like a dummy so now i'm thinking of splitting into two and freezing one and using it at a later date, maybe 2 months after i finish the first vial.
I've heard freezing one is okay, but I haven't seen an official source.
latviantower
GLP-1 Enthusiast
Freezing lypholized tirz is not only fine, but highly recommended. It will last years. Reconned tirz? I’ve read it’s ok but never tried it.
Even when you’re at a lower dosage and using a larger vial, reconned tirz should be good for several months in the fridge, so not sure you would need to try and freeze it.
Even when you’re at a lower dosage and using a larger vial, reconned tirz should be good for several months in the fridge, so not sure you would need to try and freeze it.
Soccerdude
GLP-1 Novice
I bought t60 but i'm currently at 3.5mg at that dose it would be 17 weeks out. I'm also 8 lbs from goal so as I mess with maintenance dose possibly that it will be pushed out even more,
Each of us makes his own choices on the continuum of safety etc. YMMV.
Intuitively, but not scientifically, I don't trust vial-splitting for sterility (too complicated; untrustworthy vendors; specialized equipment) but it seems everyone else who would consider it goes for it.
My go-forward plan is to recon a whole tirz-60 kit at once, and put 9 vials in the freezer; possibly moving the active one in and out of the freezer each time I pin (maybe thawing in fridge overnight?) for a little extra microbial protection.
Calm Logic
GLP-1 Specialist
At least in theory, freezing the expandable solution may lower the integrity of the vial, compromising sterility. And though tests may show purity is preserved, that does not rule out unnecessary aggregation.
Last edited:
rsmith
GLP-1 Enthusiast
Just curious about why you would recon a whole T60 kit at once and then freeze rather than recon 1 - 2 vials at a time and keep lyophilized in the freezer.
