I have acute pain in my lower back from a decades old compression injury. 15 years ago, I had a back xray and the doc said it was said I had fused vertebra...I was doing a lot of hiking at the time and there wasn't much pain. Since then, I put on some weight, and tapered off on the hiking/walking. The back has been much worse. New doc sends me for another xray, and says I have hairline fractures but the pain may also be tied to arthritis. So I get a tirz script from her and I am down 17lbs as of today. I also have been doing a couple miles of walking 3-4 times a week as I slowly build back up to hiking mode. The pain was pretty severe when I started and is way less now. Most of it I attribute to both the weight loss and the exercise...I did start on BPC-157 2 weeks ago, 250mcg. I am drug sensitive so I always opt for a low starter dose. First few doses made me dizzy, so I started pinning at night...I also started KPV a week ago, and it gave me a nice mellow feeling. Same 250mcg dose. I pin that in the AM. I gotta say, the pain has rolled off faster since the KPV...I ordered 4 kits of that... 😎 I think the BPC is doing it's thing and will stay with it. Side benefit to the BPC is that I think it is helping with the 'tirz stomach'. I pinned tirz yesterday and barely had a burp or two. I have always had to suck on some tums, particularly at night...I have a vial of TB500 and may add it to the mix once I feel sorted out on the KPV....👍