Severe Reaction of semi celeb

[lessthanhalf]

I started with name brand Zepbound at the standard starting dose. Unfortunately, I had some of the same effects although not quite as severe. I did have to wash my unders and pants once and there were a few times that I only made it because our house is so small. That side effect faded over the next few weeks and even restarting after a break on an accelerated titration schedule hasn't triggered it again.

I do agree that she's more than a little "the sky is falling!" here. Glp1s can be so tremendously beneficial to so many. Accounts like hers can do a lot of damage if she starts trotting out that people should only use them if they are the last resort.

Eli Lilly really needs to release their stranglehold on the dosing IMO. 2.5 mg-5mg-7.5mg-10mg titrating up every month is just way too much way too fast for so many and many insurance and prescribing patterns basically force people to go up whether it's medically indicated or not. My dad was very nervous about starting the meds and opted to start at 1 mg and go up 1mg each dosage increase. Impressively it's already improved his IBS symptoms.

The problem the drug companies have with the pens and dosing is the less choices they give you , the more idiot proof it is, and the more options and variations, the more likely people are going to stuff it up and get doses wrong. I think the tirzepatide dosing schedule is probably the best one, reasonably slow and consistent and way less problematic than the ozempic one of 0.25, 0.5, 1, 1.7, 2.4mg. At least with the multidose pens you can count clicks and adjust dose that way. With grey peptides you can use any dose you like and people do make dose errors more often.

 

[sheilarae74]

Now this story is ALL OVER social media now and people have been telling their ozempic horror stories. 🙄

 

[Jilla]

I started with name brand Zepbound at the standard starting dose. Unfortunately, I had some of the same effects although not quite as severe. I did have to wash my unders and pants once and there were a few times that I only made it because our house is so small. That side effect faded over the next few weeks and even restarting after a break on an accelerated titration schedule hasn't triggered it again.

I do agree that she's more than a little "the sky is falling!" here. Glp1s can be so tremendously beneficial to so many. Accounts like hers can do a lot of damage if she starts trotting out that people should only use them if they are the last resort.

Eli Lilly really needs to release their stranglehold on the dosing IMO. 2.5 mg-5mg-7.5mg-10mg titrating up every month is just way too much way too fast for so many and many insurance and prescribing patterns basically force people to go up whether it's medically indicated or not. My dad was very nervous about starting the meds and opted to start at 1 mg and go up 1mg each dosage increase. Impressively it's already improved his IBS symptoms.

I completely agree! I think Eli Lilly designed their doses for maximum weight loss to make the highest weight loss claims while making it just slow enough that they wouldn’t have a high drop out rate. These medical trials are so expensive I doubt they have any inventive to try experiment with slower dosing schedule which could offer a better experience for most patients.

It’s super frustrating as if I told my pharmacy I’m only taking a 1.25mg dose on a 2.5mg pen they'd stop prescribing me. It’s just hilarious I’m trying to take LESS of a drug not more it should be safer. It’s frustrating as it’s clear from reading in these forums the ideal dose and titration varies considerably from person to person. The side effects can be terrible for some of us. I wish mayim discussed this rather than dismissing the drugs completely.

 

[Jilla]

There does seem to be a community of people who aren't comfortable with compounded or gray (or perhaps their insurance has strong coverage), but are transferring doses from brand-name injectors into sterile empty vials, as a means of further controlling their dosing schedule.

The kwikipens we have in Europe are so good for this! You twist the pen 60 clicks for one dose so you can twist it say 30 clicks for half the dose.

It’s a shame they don’t have these in the US, but I wonder if they do it to make more money by preventing short dosing (buying a cheaper 15mg pen to take say a 5mg dose so 1 pen lasts 3 months).

 

[anotherusername]

Yes , 10 grams reconstituted with 1ml Bac. Looking at my syringe here it's a 1ml 100 U. I dosed the whole barrel . Am I screwed or not. I feel great. I was at 50 mark wich is .5 ml half 1ml syringe. The ones my guy gave me graduate from 10 to a 100 units within the 1ml tube. So you're correct I have to drop a zero off each unit example: 10 is actually 1 on this type of insulin 💉. Ya got me thinking now and I appreciate it , no lie.

Please read some more. Again I will assume you meant 10 milligrams and not actual grams. With that assumption what you’ve said is that you’ve injected 10 mg of Reta on your second dose. 12 mg is the highest dose studied. I hope you’re doing well, it appears you meant to take 10 units (1mg at that dilution)

 

[alphaskunk65]

No I injected 0.25 first time then moved to 0.5 ml for several months was losing 4lbs. a week steady . Hit the wall so I upped to 0.75 ml for 1 month hit the wall quicker upped to 1.0 ml . You should see in my reply post earlier that these particular syringes read powers of 10. I misquoted. It's still a 1 ml max dose syringe but says 100 units on side.Its actually 10 max. Thanks for your concern GLP brother or sister. Not sure what the 100 units is of it doesn't confront me.

 

[randompersonrandom]

I'm not mad at Balik, she's had a hard go of it and mostly just wrote what happened to her. But can we talk about how shitty "The Big Bang Theory" was? I'm usually pretty good about just letting people enjoy things and not being one of those people who has to yell about what they hate like a totally unparented eight year old in the grocery store, but I'm getting on in years and that show is so relentlessly speed-stupid, just a constant stream of noisy, clowning dumb. It's like Teletubbies for very stupid adults. I hate it so much, and I'm angry every time someone reminds me it exists.

 

[CandyCap]

No I injected 0.25 first time then moved to 0.5 ml for several months was losing 4lbs. a week steady . Hit the wall so I upped to 0.75 ml for 1 month hit the wall quicker upped to 1.0 ml . You should see in my reply post earlier that these particular syringes read powers of 10. I misquoted. It's still a 1 ml max dose syringe but says 100 units on side.Its actually 10 max. Thanks for your concern GLP brother or sister. Not sure what the 100 units is of it doesn't confront me.

ML an units are not really ways to measure how much you are taking. You need to know how many mg you are taking. How many mg is in your vial? How much BAC? Those are the important number to start with. It is also very important to understand the difference between a gram and a milligram. Can you please clarify how many milligrams are in your vial? How much BAC was used?

 

[alphaskunk65]

20 MG with 2ml of Bac. So 1 full syringe at 1ml. should be 10mg dose I believe. Since there's only 1ml. Bac per 10 MG of Reta maybe I said gram instead of MG. Either way I started with 1/4 of 1ml syringe upped respectively to 1/2 then 3/4 and now to 1 full ml. Worded different same dose . My nomenclature may need polished a bit. Don't get me started on decimal points tho I understand it's important in case newbie like me reads my post as gospel.

 

[alphaskunk65]

Did it again. .1ml

 

[BrightCandle]

So you definitely took 10mg then. That is very near the maximum dose (12mg) from the trial. Most start in the 1-2mg range.

 

[alphaskunk65]

Yes worked up to that over 7 month period. My syringe however says 1ml not .1ml . The one I reconstitute with says 3ml/cc.

 

[alphaskunk65]

If go to your calculator and add 0.5 to 0.5 it will equal 1.0 ml hope that makes sense. So I'm close to max dose , wich I know one crazy guy is dosing over that , I think his is Tirz.

 

[alphaskunk65]

So you definitely took 10mg then. That is very near the maximum dose (12mg) from the trial. Most start in the 1-2mg range.

Sorry I didn't direct reply to you answer is in this thread. I'm still honing my skills.

 

[Month]

No I injected 0.25 first time then moved to 0.5

So you definitely took 10mg then. That is very near the maximum dose (12mg) from the trial. Most start in the 1-2mg range.

kind of fast but not that bad, as far as I understand his first dose was 2.5mg, that's not far off the 2mg dose, and then he increased the next dose to 5mg, now that's the biggest and quickest increase, in just 1 week he got 6.25mg(5mg + 2.5/2 from half-life), but some people are genetically resistant to it, and then he kept it normal and increased it to 7.5 and then to 10, which in studies its usually 6 to 8 to 10 so again a little fast but not too crazy.

 

[alphaskunk65]

kind of fast but not that bad, as far as I understand his first dose was 2.5mg, that's not far off the 2mg dose, and then he increased the next dose to 5mg, now that's the biggest and quickest increase, in just 1 week he got 6.25mg(5mg + 2.5/2 from half-life), but some people are genetically resistant to it, and then he kept it normal and increased it to 7.5 and then to 10, which in studies its usually 6 to 8 to 10 so again a little fast but not too crazy.

Yes I was told by my suppliers contact. I then hit up the search bar for Reta dosing from start to maintenence dosing. It recommended what you said above. Remember from 2nd week until 2 months ago I stayed at 0.5 MG or ml it's the Same because of how I reconstituted. Also took a peak at dosing calculator. Some sites I read if a person is severely obese skip 2.5 gr and try .5 for first stick and see how it works. None of this is in any way my recommendation. Do you! !