Nexaph

[exploitedworkerbee]

Like these beauties?

lol I can’t believe they shipped that. Poor babacain is gonna have to issue yet another assurance that product integrity is their highest priority just a week after the last time he had to 🤣 I’m starting to wonder if that’s just hollow damage control marketing speak.

 

[raw_oyster_eater]

I checked over there to see if he put it up as "ugly NAD"

not yet. always looking for bargains.

I'll buy anybody's bum stuff for a buck or two a vial.

 

[Calm Logic]

but the stability of their buffered solution during the lyophilization process is still flawed. I did get 2 other kits which were as perfect looking as this one was ugly. I am most interested to see how this batch as a whole tests out.

The first person who posted about "bad" NAD+ had vials that looked perfect as well (before the picture was deleted).

So to make sense of the madness, I had to ask what else may be at play:

Reasons for Differential Degradation in Lyophilized Vials:

Even with seemingly identical vials of freeze-dried powder, variations in storage or processing can lead to some degrading more than others:

1. Residual Moisture Content: This is arguably the most critical factor for lyophilized products.
   • Incomplete Drying: If some vials didn't undergo complete drying during the lyophilization process, they would have higher residual moisture. Even a tiny amount of water can significantly accelerate degradation of NAD+.
     
     
   • Moisture Ingress: A compromised vial seal (even a microscopic defect) can allow ambient humidity to slowly ingress into the vial, rehydrating the powder and triggering degradation. This can happen during storage or shipping.
2. Temperature Excursions:While lyophilized powder is more robust than solution, extreme or prolonged heat can still cause degradation.
   • Localized Hot Spots: During shipping or storage, some vials might have been exposed to warmer temperatures for longer periods or to higher peak temperatures within a batch.
     
     
   • Fluctuations: Repeated temperature cycling (even if within recommended storage ranges) can stress the powder and potentially exacerbate degradation.
3. Light Exposure: NAD+ is generally sensitive to light, especially UV light. If some vials were exposed to light more than others, it could contribute to their degradation, though this is usually secondary to moisture and temperature.
   
   
4. Oxygen Exposure / Seal Integrity: Oxygen can also contribute to NAD+ degradation. If a vial's seal is not perfectly hermetic, it could allow oxygen in, leading to oxidation and degradation.
   
   
5. Initial Purity and Consistency:
   • Raw Material Quality: While unlikely from reputable suppliers, slight variations in the initial purity of the NAD+ used for different vials could influence their long-term stability.
     
     
   • Manufacturing Variability: Even with strict GMP (Good Manufacturing Practice) standards, minor inconsistencies during the lyophilization process (e.g., slight differences in freezing rate, vacuum levels, or drying time for individual vials) could result in subtle differences in the final powder structure and stability.
6. Static Electricity/Handling: In rare cases, electrostatic charges or excessive agitation during handling could potentially contribute to subtle changes in the powder's physical structure, making it slightly more susceptible to moisture or other degradation pathways, though this is less likely to cause significant visual degradation.

 

[Divide By Zero]

I was sent vials of NAD+ that suffer from straight-up meltback... not crystallization. Confirmed by an actual (retired) chemist, not a vendor (Cain) that just seems bent on gaslighting everyone. Meltback is definitely a problem, and I find it laughable Cain tries to say it "tested" fine when he has kits of widely varying quality and condition being sent out sight-unseen. It is also laughable that he likes to posture himself as some "stand up guy," offering refunds for bad kits, when he turns right around and arbitrarily decides "that's good to go.. it's just crystallization." Partial refunds are also a joke; he should be refunding people in full and abandoning this entire product until whoever is manufacturing it gets their crap together. There seems to be a very large set of people (disciples) hellbent on refusing to believe Cain (cult leader) is not perfect and very much want to believe everything he says. Cain relies on people's ignorance in situations like this and selectively refunds those he thinks will run the most "interference" defending his... uh... honor (cough). The need to believe is very strong with this guy. He should have just cut his losses, admitted it's crap, refunded everyone, and taken up all complaints with his source. I shouldn't have to even know what "meltback" is... unfortunately due to Cain, I do now.

 

[Calm Logic]

Does anyone do NAD right, consistently? There are complaints here about PGB too over NAD.

 

[chmuse]

I was sent vials of NAD+ that suffer from straight-up meltback... not crystallization. Confirmed by an actual (retired) chemist, not a vendor (Cain) that just seems bent on gaslighting everyone. Meltback is definitely a problem, and I find it laughable Cain tries to say it "tested" fine when he has kits of widely varying quality and condition being sent out sight-unseen. It is also laughable that he likes to posture himself as some "stand up guy," offering refunds for bad kits, when he turns right around and arbitrarily decides "that's good to go.. it's just crystallization." Partial refunds are also a joke; he should be refunding people in full and abandoning this entire product until whoever is manufacturing it gets their crap together. There seems to be a very large set of people (disciples) hellbent on refusing to believe Cain (cult leader) is not perfect and very much want to believe everything he says. Cain relies on people's ignorance in situations like this and selectively refunds those he thinks will run the most "interference" defending his... uh... honor (cough). The need to believe is very strong with this guy. He should have just cut his losses, admitted it's crap, refunded everyone, and taken up all complaints with his source. I shouldn't have to even know what "meltback" is... unfortunately due to Cain, I do now.

Yeah, until now I'd been using him as a 'I need something fast I'll just pay the premium' but I'm not sure he can come back from this one in my eyes. These kits should have never been sent out, especially not at his usual mark up.

 

[Peloma]

Bristaxx said that unbuffered Nad+ is the way to go because what you see in those previous pics is the result of the buffer separation. The buffer also adds a level of instability that degrades the Nad faster.

Buffer your own as needed with sodium bicarbonate, and ugly Nad shouldn't be an issue.

 

[Ted R]

Bristaxx said that unbuffered Nad+ is the way to go because what you see in those previous pics is the result of the buffer separation. The buffer also adds a level of instability that degrades the Nad faster.

Buffer your own as needed with sodium bicarbonate, and ugly Nad shouldn't be an issue.

I was sent vials of NAD+ that suffer from straight-up meltback... not crystallization. Confirmed by an actual (retired) chemist, not a vendor (Cain) that just seems bent on gaslighting everyone. Meltback is definitely a problem, and I find it laughable Cain tries to say it "tested" fine when he has kits of widely varying quality and condition being sent out sight-unseen. It is also laughable that he likes to posture himself as some "stand up guy," offering refunds for bad kits, when he turns right around and arbitrarily decides "that's good to go.. it's just crystallization." Partial refunds are also a joke; he should be refunding people in full and abandoning this entire product until whoever is manufacturing it gets their crap together. There seems to be a very large set of people (disciples) hellbent on refusing to believe Cain (cult leader) is not perfect and very much want to believe everything he says. Cain relies on people's ignorance in situations like this and selectively refunds those he thinks will run the most "interference" defending his... uh... honor (cough). The need to believe is very strong with this guy. He should have just cut his losses, admitted it's crap, refunded everyone, and taken up all complaints with his source. I shouldn't have to even know what "meltback" is... unfortunately due to Cain, I do now.

Here is Janoshik's vendor supplied test report for this batch. Note the attached pics (scroll all the way to the last pics) that show most if not all have at least some degree of melting and they still tested from ~495 to ~584. Definitely he has some work to do to improve the puck quality but all in all not too bad.

Janoshik Analytical

 

[Calm Logic]

I would be filtering (as always):

When the lyophilized NAD+ melts, it re-enters a liquid state. This immediately increases the risk of microbial growth for several reasons:

• Reabsorption of Moisture: The melting implies moisture re-entry, creating an aqueous environment that many microorganisms need to thrive.
  
  
• Exposure to Environment: Unless the melting occurred within a completely sterile, sealed, and undamaged vial, there's a risk of environmental contamination. Even microscopic cracks in the stopper or vial, or improper handling during storage, could allow airborne microbes or those from surfaces to enter the now-liquid product.
  
  
• Breach of Aseptic Seal: The integrity of the vial's seal (stopper, crimp) is crucial for maintaining sterility. Melting and subsequent re-solidification (if it happens) can stress the stopper and potentially compromise the seal, allowing ingress of contaminants.
  
  
• Nutrient Availability: NAD+ itself, or any excipients in the formulation (like sugars or buffers), can serve as nutrients for microbial growth if contamination occurs.

 

[zpped]

Here is Janoshik's vendor supplied test report for this batch. Note the attached pics (scroll all the way to the last pics) that show most if not all have at least some degree of melting and they still tested from ~495 to ~584. Definitely he has some work to do to improve the puck quality but all in all not too bad.

Janoshik Analytical

Any issue is almost certainly going to manifest as premature degradation. What's it going to test like in 6 months? Or how is it going to compare to other NAD 1-2 weeks after reconstitution?

 

[ironbull]

Just ordered from nexaph to Canada
Cleared customs within an hour.. delivery was 3 days from ordering. Impressive

 

[ironbull]

Not sure what is bad but properly buffered NAD+ is light yellow. If it's dark yellow then it's oxidized. I brew my own NAD+ and have messed up many batches. Even with it oxidized it will still give some benifits and the oxidized portion just converts to NADH. Not exactly what we are looking for but it will still give some benifits.

I just buy bulk nmn and that boosts nad levels very well

 

[Calm Logic]

I am planning on using oral NMNH (which seems better than NMN at raising NAD levels in the body as a whole, at least in mice). But I'm sure I will try NAD subq at some point.

 

[ironbull]

I am planning on using oral NMNH (which seems better than NMN at raising NAD levels in the body as a whole, at least in mice). But I'm sure I will try NAD subq at some point.

this must be newer.. i havent seen this listed for sale yet on some of the main sources for NMN... NMN works great already.. I'm taking a gram of NMN daily .. do you have to take as much in that form to get the same results?

 

[Calm Logic]

Yes, the same amount of NMNH (like the kind sold at Amazon), to provide superior results if anything, especially to other tissues and not just the bloodstream.

1.5 grams may be even better:

https://www.nmn.com/news/nmnh-substantially-raises-nad-levels-more-than-nmn

"The dosages used in these mice were 250 mg/kg injections or about 1.5 grams for adults weighing about 165 pounds. These results suggest that NMNH more effectively increases blood NAD+ compared to NMN."

 

[Fisherman2356]

I just buy bulk nmn

Source please?

 

[exploitedworkerbee]

I was sent vials of NAD+ that suffer from straight-up meltback... not crystallization. Confirmed by an actual (retired) chemist, not a vendor (Cain) that just seems bent on gaslighting everyone. Meltback is definitely a problem, and I find it laughable Cain tries to say it "tested" fine when he has kits of widely varying quality and condition being sent out sight-unseen. It is also laughable that he likes to posture himself as some "stand up guy," offering refunds for bad kits, when he turns right around and arbitrarily decides "that's good to go.. it's just crystallization." Partial refunds are also a joke; he should be refunding people in full and abandoning this entire product until whoever is manufacturing it gets their crap together. There seems to be a very large set of people (disciples) hellbent on refusing to believe Cain (cult leader) is not perfect and very much want to believe everything he says. Cain relies on people's ignorance in situations like this and selectively refunds those he thinks will run the most "interference" defending his... uh... honor (cough). The need to believe is very strong with this guy. He should have just cut his losses, admitted it's crap, refunded everyone, and taken up all complaints with his source. I shouldn't have to even know what "meltback" is... unfortunately due to Cain, I do now.

He publicly admitted he is learning on the job while he builds out his domestic “lab” (most likely his garage, but maybe basement). How people have become so brainwashed that they accept this for stuff they’re shooting into their bodies i guess speaks to the power of self-deception. They want these meds so badly and are so resistant to paying with anything but a credit card that they have decided that literal sludge is an OK thing to ship 🤯 It’s not even priced competitively! I just don’t get it.

 

[zpped]

He publicly admitted he is learning on the job while he builds out his domestic “lab” (most likely his garage, but maybe basement). How people have become so brainwashed that they accept this for stuff they’re shooting into their bodies i guess speaks to the power of self-deception. They want these meds so badly and are so resistant to paying with anything but a credit card that they have decided that literal sludge is an OK thing to ship 🤯 It’s not even priced competitively! I just don’t get it.

Because people will stop talking about this in a few weeks and then 20 people that have joined in the meantime will chime in to say "he's been reliable for me" and then 3 months from now he'll make another stupid mistake and we'll do it all over again.

 

[chmuse]

He publicly admitted he is learning on the job while he builds out his domestic “lab” (most likely his garage, but maybe basement). How people have become so brainwashed that they accept this for stuff they’re shooting into their bodies i guess speaks to the power of self-deception. They want these meds so badly and are so resistant to paying with anything but a credit card that they have decided that literal sludge is an OK thing to ship 🤯 It’s not even priced competitively! I just don’t get it.

For me it was always the testing aspect. He tests, then pays for a test, then a third party test. So I figured every thing else aside if it tested well... And frankly everyone so desperate to prove his product was bad, I was confident I'd hear about it.

Now I know the history and understand a bit better what testing can and cannot tell you. I found a post from you from I think October or November where you said to test his stuff again in a year because there was no way of knowing its rate of degradation when all the testing happens right away. And I have a batch I'm not willing to pay to retest that I just won't use because it doesn't work after two weeks of being reconned. 🤷‍♀️ You live you learn. Sucks posts can't be edited after a bit. I get the reasoning, but I said a lot of stupid shit when I was new.

 

[nutsEOLRN]

For me it was always the testing aspect. He tests, then pays for a test, then a third party test. So I figured every thing else aside if it tested well... And frankly everyone so desperate to prove his product was bad, I was confident I'd hear about it.

Now I know the history and understand a bit better what testing can and cannot tell you. I found a post from you from I think October or November where you said to test his stuff again in a year because there was no way of knowing its rate of degradation when all the testing happens right away. And I have a batch I'm not willing to pay to retest that I just won't use because it doesn't work after two weeks of being reconned. 🤷‍♀️ You live you learn. Sucks posts can't be edited after a bit. I get the reasoning, but I said a lot of stupid shit when I was new.

Now I am super interested in knowing what the batch tests at. I have purchased soo many kits from him and this thread is honestly the first I have read about all of this. Despite being in those groups, I can't find the confession or anything other than this. I tried looking last night. I thought I found gold when I found nexaph. I like that purchasing from the website is straight forward but like someone else mentioned, wait till PayPal finds out. I did ask the mods what their security plan was or how they planned to protect Nexaph as the number of members went from 4K to over 8K in 1 month. The mods went around in circles with answers and never gave me an actual answer. I was confused about the merchandise they had on the website. why are we advertising?!

 

[zacharyjl3]

I’m in the STG telegram and they don’t recommend Nexaph? Is that correct? Supposedly they removed them from approved vendors?

Why not? I just ordered from them.

 

[kjones1122]

How often are the Retatrutide kits restocked?

 

[nutsEOLRN]

How often are the Retatrutide kits restocked?

people are constantly asking as soon as that last kit is sold. mods usually say "within a week or so"

 

[chmuse]

Now I am super interested in knowing what the batch tests at. I have purchased soo many kits from him and this thread is honestly the first I have read about all of this. Despite being in those groups, I can't find the confession or anything other than this. I tried looking last night. I thought I found gold when I found nexaph. I like that purchasing from the website is straight forward but like someone else mentioned, wait till PayPal finds out. I did ask the mods what their security plan was or how they planned to protect Nexaph as the number of members went from 4K to over 8K in 1 month. The mods went around in circles with answers and never gave me an actual answer. I was confused about the merchandise they had on the website. why are we advertising?!

I think the issue is probably not in the puck itself, but in how long it lasts in the fridge. I have another kit from them that doesn't have that issue, and ones from other companies that don't have that issue.

I honestly suspect they'll pull a amo/bff and make a new website with someone else's PayPal info or something. Maybe go with alipay.

There was a whole todo last summer/fall, RIGHT before I started pepping. So all my knowledge is secondhand from asking the oldies and digging through old discord and forum threads.

 

[chmuse]

Why not? I just ordered from them.

Interpersonal drama that has nothing to do with the product itself.

 

[exploitedworkerbee]

Interpersonal drama that has nothing to do with the product itself.

That’s how nexa framed the response to their deceitful behavior, which was a concern precisely because it foreshadowed the behavior we’re seeing now. It is very much related to product quality.

 

[chmuse]

That’s how nexa framed the response to their deceitful behavior, which was a concern precisely because it foreshadowed the behavior we’re seeing now. It is very much related to product quality.

I'm talking specifically about the STG incident, though I suppose I could have been given the wrong story. The screenshots seemed to corroborate that it was a misunderstanding.

 

[exploitedworkerbee]

I'm talking specifically about the STG incident, though I suppose I could have been given the wrong story. The screenshots seemed to corroborate that it was a misunderstanding.

ah gotcha. i don't know much about that.

 

[Rolefun]

That’s how nexa framed the response to their deceitful behavior, which was a concern precisely because it foreshadowed the behavior we’re seeing now. It is very much related to product quality.

What is happening with them? I just made an order with them and now I am concerned?

 

[Calm Logic]

Nothing new to worry about, IMHO. Just think twice before getting NAD+ from them.