Cagrillintide questions

A1stg

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I’m just wondering how long it takes cagrillintide to suppress appetite and if anyone is using or has used it by itself and what were the effects.
 
The first time I dosed 250mcg (1/4 of a milligram), I couldn't eat for almost two days.
Other people need 1-2+ mg to feel it.
It varies from person to person and you won't know what works for you until you try it.
 
peptideusername said:
The first time I dosed 250mcg (1/4 of a milligram), I couldn't eat for almost two days.
Other people need 1-2+ mg to feel it.
It varies from person to person and you won't know what works for you until you try it.
Click to expand...
Was that the day after you pinned it or a couple days after
 
peptideusername said:
The first time I dosed 250mcg (1/4 of a milligram), I couldn't eat for almost two days.
Other people need 1-2+ mg to feel it.
It varies from person to person and you won't know what works for you until you try it.
Click to expand...
Put another way, start low but don’t be scared to bump it up if it isn’t working. just because you see lightweights like @peptideusername here losing it after a measly 1/4 of a mg doesn’t necessarily mean you are going to be such a candy ass; you might need an actual dose to have an effect.
 
I started at 0.3 mg and incremented it monthly by 0.1 mg until I hit my sweet spot which for me has been 0.7 mg. I haven't increased the dosage in 4 months and use it for maintenence. It's the most potent weight-loss peptide in my experience.

Early on I upped the dosage from 0.4 mg to 0.7 mg and was barely able to work that week. Every day I would come home from work and sleep right away, leaving my chores and paperwork. Now it's the weight-loss peptide that gives me the least side effects.
 
Definitely start small; some of us it hits hard. You can always add more. There are some people it doesn't hit until 1+ mg and I'm pretty sure there's at least one person here taking like 3mg a week.

I started at half what peptideusername was using (.125mg) and in the end, I just passed it on to some friends. Wasn't worth feeling so sick for me, especially since I wasn't losing any more than before. For most people, it just results in less appetite and maybe some nausea.
 
I started at 0.13mg a week, six months ago. For peps, I often start with only a 10% dose to test my tolerance. The appetite suppression started within a few days. Even at 0.13mg, I felt quite nauseous for a few weeks, less later on, but still present. I stopped 3 weeks ago (was at 0.9mg a week). I had a nice burger and it now tasted good. While on Cagri, a lot of smells I could not tolerate, like beef. It was suppressing my appetite, but in an awful way, for me. I normally never get nauseous.
 
chmuse said:
Definitely start small; some of us it hits hard. You can always add more. There are some people it doesn't hit until 1+ mg and I'm pretty sure there's at least one person here taking like 3mg a week.

I started at half what peptideusername was using (.125mg) and in the end, I just passed it on to some friends. Wasn't worth feeling so sick for me, especially since I wasn't losing any more than before. For most people, it just results in less appetite and maybe some nausea.
Click to expand...
They trialed it as high as 4.5mg. If it works for you low then that is awesome and you should definitely try that first, but I don’t know where this idea came from that people should expect to dose it down in the sub-mg range outside of titration.
 
exploitedworkerbee said:
They trialed it as high as 4.5mg. If it works for you low then that is awesome and you should definitely try that first, but I don’t know where this idea came from that people should expect to dose it down in the sub-mg range outside of titration.
Click to expand...
As a starting dose? The study I looked at started with equal parts sema and cagri at .25 each. I started lower, knowing both that I'm sensitive and I was already on a higher sema dose. They may have gone as high as 4.5, but they started significantly lower 🤷‍♀️ And anecdotal reports on this forum also show a wide variety of tolerances. I wasn't saying to stay small, I was saying to start small and see how you feel.

Part of it is probably more to do with price- up until recently it wasn't all that cheap for something most people use as a booster rather than their primary choice for weight loss.
 
I don't have any adverse side effects and have been taking Cagri for 10 months. I noticed my 5mg Tirz appetite suppression continuing through days 5 and 6 at about 1mg Cagri but no difference up to that point. I thought I had bad product so 3 different vendors yielded the same non result. I'm now up to 2.2mg for same effect w/o ever having had to increase my Tirz dose from 5mg. I've been maintaining below goal.

It's wise with any peptide to start with a minimum dose to test tolerance.
 
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chmuse said:
As a starting dose? The study I looked at started with equal parts sema and cagri at .25 each. I started lower, knowing both that I'm sensitive and I was already on a higher sema dose. They may have gone as high as 4.5, but they started significantly lower 🤷‍♀️ And anecdotal reports on this forum also show a wide variety of tolerances. I wasn't saying to stay small, I was saying to start small and see how you feel.

Part of it is probably more to do with price- up until recently it wasn't all that cheap for something most people use as a booster rather than their primary choice for weight loss.
Click to expand...
Yah for sure you’ll want to start with a low dose, it would be a very bad idea to take 4.5mg as a starting dose, sorry if i wasn’t clear. My critique is simply that I see a lot of people be like “I’m taking 500mcg of cagri and it isn’t doing anything!” so letting folks know that it isn’t crazy to get into larger doses than that.
 
About 24 hours for me to notice it. Maybe 28. They say it builds up in your system because the half life is greater than 7 days. I took it about three weeks till I broke my stall and went back to pure tirz.
 
exploitedworkerbee said:
Yah for sure you’ll want to start with a low dose, it would be a very bad idea to take 4.5mg as a starting dose, sorry if i wasn’t clear. My critique is simply that I see a lot of people be like “I’m taking 500mcg of cagri and it isn’t doing anything!” so letting folks know that it isn’t crazy to get into larger doses than that.
Click to expand...
Same goes for the "2mg of Reta isn't making me thin" crowd
 
A1stg said:
I’m just wondering how long it takes cagrillintide to suppress appetite and if anyone is using or has used it by itself and what were the effects.
Click to expand...
I took 0.18mg and slept until 11pm the next day. Tried again the following week and slept until 8pm. And no appetite suppression. It's a no go for me.
 
Peotidethrowaway said:
I started at 250mcg for 4 weeks or so with no effects whatsoever. Bumped it to 500mcg this week and I feel it’s working perfect for me
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I did the same. Been at 500mcg for few weeks now and suppression works well, but still eat, really small. No issues to note. I pin 1x weekly, in the evening couple hours before bed.
 
peptideusername said:
The first time I dosed 250mcg (1/4 of a milligram), I couldn't eat for almost two days.
Other people need 1-2+ mg to feel it.
It varies from person to person and you won't know what works for you until you try it.
Click to expand...
I just made the mistake of doing 1mg with my Triz 2 days ago. Wanna guess when the last time I ate ANYTHING was???

Proper Cargi is very potent. Start low and work your way up. Because taking it back takes days of regret.
 
gimmeshelter said:
late to this ---- could we pair w reta? would that make any sense?
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Might make sense, if you're hitting the max on Reta and stalling or the food noise is getting too much. Cagri does a pretty good job with that. I didn't need to add anything to Reta even though it seemed like my sweet tooth came back a bit switching from Tirz, I was still losing weight or keeping it off. Only negative I've heard on Cagri other than standard sides, is that it seems like the amylin receptor response (or the perceived effect) declines with time. So people tend to use it for a while, titrate up a bit, and move to something else. The standard method is to offset it by a few days from the Reta/Tirz so that you get consistent hunger suppression.

But I'm just talking in anecdotes here. Better to find someone with personal experience!
 
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gimmeshelter said:
late to this ---- could we pair w reta? would that make any sense?
Click to expand...
I added cagri to reta pretty quickly because I simply wanted to try it and could get a single vial for a good price. I'm only on about 5 mg of reta weekly, but I noticed the appetite reduction wasn't as pronounced as on ozempic, which I was on previously. I started with 250 mcg cagri per week. Noticed it on the second day, and it stopped me from eating nearly entirely by the third.

I'm supposed to have my third injection of 250 mcg today, but I'm not sure if I will. It has gotten a little better, I am able to keep eating after a couple bites, but I have been below 1000 calories a day for the vast majority of days since taking cagri. A lot of it is due to my own lack of willpower to push through the suppression, but still. I also take vyvanse which suppresses appetite, and while I can eat through it when I'm not taking these peptides, I think it may remove any leftover hunger signals I would get without it.

Safe to say it definitely works for me, but be cautious!
 
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retarequired said:
I added cagri to reta pretty quickly because I simply wanted to try it and could get a single vial for a good price. I'm only on about 5 mg of reta weekly, but I noticed the appetite reduction wasn't as pronounced as on ozempic, which I was on previously. I started with 250 mcg cagri per week. Noticed it on the second day and pretty much stopped me from eating entirely by the third. Safe to say it definitely works for me, but be cautious!
Click to expand...
I was on 9mg Reta q6d and was noticing my food noise was returning on ~5th day of my cycle. I added 1mg Cag q3d on an alternating schedule and totally lost the food noise and experienced good satiety also. Most effect was apparent on start of 2nd day after inj.
 
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