Yes this is what I've been reading.. Instead of having a break I've just added Tirz to my high dose of Reta..I have my last few stubborn KGs to loose.. I'm thinking if I have a break,second time around it'll be pointless..Following. I’ve heard for some it never gives them the same suppression after they’ve stopped and restarted, and for others they do.
Same..I've decided just to add Tirzapzide to my Retatutide,but ultimately at one point I'll either have to drop to maintenance dose or have a break..So far there's mixed Opinions..I’m interested to see if anyone has direct experience with this.
I’ve been on Sema (.2/wk) and Reta (.7/wk) with no intention of coming off at any point. Would you consider lowering to your starting dose again so you don’t have to suffer the same acclimation symptoms? When you get a prescription they make you start over if you’ve been off for 5 weeks which leads me to believe that’s the point at which the stacked half-lives are fully depleted.Anyone been on a high dose of Tirz or Reta,then it slowed down and you took a break to 'reset'?
If so how long was it for,and did it work??
Why such low doses of both though? Wouldn't it be better to Tirate up one first?I’ve been on Sema (.2/wk) and Reta (.7/wk) with no intention of coming off at any point. Would you consider lowering to your starting dose again so you don’t have to suffer the same acclimation symptoms? When you get a prescription they make you start over if you’ve been off for 5 weeks which leads me to believe that’s the point at which the stacked half-lives are fully depleted.
My BMI is 20 and I find it hard to gain weight already. I’m microdosing to suppress the activation of microglia and astrocytes, as well as the neuroprotective mechanisms like synaptic plasticity and enhancing the expression of BDNF. I also like the accelerated wound healing and anti-inflammation. I tried .5-1mg Sema and 1-2mg Reta at one point, lost 13 lbs in under a month and looked like I was starving to death. I also lost all my energy, bad combo.Why such low doses of both though? Wouldn't it be better to Tirate up one first?