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Chart Showing Comparative Activation of Different Receptors by GLP-1 Drugs Involved

keangkong

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I saw a chart repeatedly showing the supposed potencies of different weight loss drugs in humans. I assumed that the information in it was wrong, but when I checked, everything matched scholarly sources.

The profiled drugs are semaglutide, tirzepatide, retatrutide, mazdutide, and survodutide.

I realize that there are caveats I should be adding on using the data but I'm so inexpert in this field that I can't even explain well the reason for the caveats.

I'm adding an image of the chart along with sources. I'm also attaching a .pdf document, which will permit you to click on the hyperlinks in order to access the source documents without having to go through a paywall.
 

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