Goal reached in 9 months - 55 year old, male, 5'5" (Tirz/Cagri combo)

[Leg Show Magazine]

Tirzepatide on Sundays.
Cagrilintide on Thursdays.
December 2024: 215 lbs.
September 2025: 144 lbs.

Followed the typical dosage charts (dose increases every 4 weeks until max. recommended) without any significant side effects.
Weighted myself at the 6-month mark (165 lbs) and 9-month mark.

Will start weekly exercise routine soon (4x/week).

Currently, going backwards on my Tirz dose in order to switch to Reta (2x agonist->3x agonist) for maintenance purpose. My intention is to drop Reta or Cagri in the future.

 

[GLP1Pharmacist]

Wow, congratulations! On a 2 year journey myself which I hope to be at goal.

 

[vewdew34]

Congratulations Reaching your goal, I am almost there 10lb to go.

 

[mlke6]

Tirzepatide on Sundays.
Cagrilintide on Thursdays.
December 2024: 215 lbs.
September 2025: 144 lbs.

Followed the typical dosage charts (dose increases every 4 weeks until max. recommended) without any significant side effects.
Weighted myself at the 6-month mark (165 lbs) and 9-month mark.

Will start weekly exercise routine soon (4x/week).

Currently, going backwards on my Tirz dose in order to switch to Reta (2x agonist->3x agonist) for maintenance purpose. My intention is to drop Reta or Cagri in the future.

How are you doing mentally with your new body?

 

[Bunny]

Congratulations. Enjoy. 😁

 

[Morbius]

Will start weekly exercise routine soon (4x/week).

If you have lost that much weight without doing exercise along the way you may be shocked at how much lean muscle mass you have lost.

I recently hit what I thought was my goal weight, and I got a DEXA scan, and it was bad news... 33% body fat with a very high visceral fat score. I'm like 3rd percentile for muscle mass in my age group, despite currently not looking fat.

"They" say I was supposed to be exercising all along the way, and eating enough protein. Turns out, they were right. Now I am trying to fix my body composition, that's probably going to be hard at my age.

 

[MsGizmo]

Tirzepatide on Sundays.
Cagrilintide on Thursdays.
December 2024: 215 lbs.
September 2025: 144 lbs.

Followed the typical dosage charts (dose increases every 4 weeks until max. recommended) without any significant side effects.
Weighted myself at the 6-month mark (165 lbs) and 9-month mark.

Will start weekly exercise routine soon (4x/week).

Currently, going backwards on my Tirz dose in order to switch to Reta (2x agonist->3x agonist) for maintenance purpose. My intention is to drop Reta or Cagri in the future.

Always good to see someone reaching their goal while losing at a healthy rate. Congratulations!

 

[Leg Show Magazine]

How are you doing mentally with your new body?

I feel more confident in public. Generally speaking I'm happy since I have not weighted this little since my late teens, early twenties.

 

[Leg Show Magazine]

If you have lost that much weight without doing exercise along the way you may be shocked at how much lean muscle mass you have lost.

Yes, I was aware of that side effect prior to starting the process so I also added a once-a-day Glycine supplement to my routine.

 

[Fisherman2356]

If you have lost that much weight without doing exercise along the way you may be shocked at how much lean muscle mass you have lost.

I recently hit what I thought was my goal weight, and I got a DEXA scan, and it was bad news... 33% body fat with a very high visceral fat score. I'm like 3rd percentile for muscle mass in my age group, despite currently not looking fat.

"They" say I was supposed to be exercising all along the way, and eating enough protein. Turns out, they were right. Now I am trying to fix my body composition, that's probably going to be hard at my age.

HGH with exercise and you'll be bulging in no time. Same thing happened to me (lost a lot of muscle, not exercising) and after doing 3iu five times a week for about 5-6 weeks my muscles have bounced back and then some. I ain't a spring chicken by no means either LOL, late 50's but in great health and shape. The weight has bounced back also though lol. Initially lost 35lbs and have gained back about 15lbs but I think the whole 15lbs is muscle gain as I am same or a bit stronger than originally (pre GLP1).

 

[Fisherman2356]

so I also added a once-a-day Glycine supplement to my routine

Curious to know what Glycine is supposed to do especially with regards to muscle loss? I'd heard Carnitine is supposed to help but have no experience of my own.

 

[Fisherman2356]

Tirzepatide on Sundays.
Cagrilintide on Thursdays.
December 2024: 215 lbs.
September 2025: 144 lbs.

Followed the typical dosage charts (dose increases every 4 weeks until max. recommended) without any significant side effects.
Weighted myself at the 6-month mark (165 lbs) and 9-month mark.

Will start weekly exercise routine soon (4x/week).

Currently, going backwards on my Tirz dose in order to switch to Reta (2x agonist->3x agonist) for maintenance purpose. My intention is to drop Reta or Cagri in the future.

What was your Cagri dose?

 

[Leg Show Magazine]

What was your Cagri dose?

I followed the attached chart / table. 2.4mg was my maximum dose, and that remains my weekly dose.

 

[Leg Show Magazine]

Curious to know what Glycine is supposed to do especially with regards to muscle loss? I'd heard Carnitine is supposed to help but have no experience of my own.

A Googled "glycine supplement benefits" and the AI overview mentions "Enhanced Muscle Growth and Recovery" as one of the benefits as well as:
-Improved Sleep Quality
-Reduced Oxidative Stress
-Improved Blood Sugar Control
-Reduced Inflammation
-Improved Liver Health
Other Potential Benefits: May support healthy aging, May improve cognitive function, May promote wound healing, and May reduce the risk of certain cancers.

 

[Fisherman2356]

A Googled "glycine supplement benefits" and the AI overview mentions "Enhanced Muscle Growth and Recovery" as one of the benefits as well as:
-Improved Sleep Quality
-Reduced Oxidative Stress
-Improved Blood Sugar Control
-Reduced Inflammation
-Improved Liver Health
Other Potential Benefits: May support healthy aging, May improve cognitive function, May promote wound healing, and May reduce the risk of certain cancers.

I actually been taking Glycine (pretty high amounts) for past year or so but can't attest to any benefits you list above. No effect on inflammation for sure as I have an autoimmune condition and have plenty inflammation and glycine is not on the list of things that has helped me. I didn't notice any help with sleep either, no effect on blood sugar, the other two are just subjective IMO. Having said all that, I still think of it as a net positive for overall health, but I find it to be a bit overrated.