Hi friends!

[Pinmebaby1moretime]

So lucky to have found you all! I’ve been silently reading everything for the past two weeks- finally made an account to join the fun. My RS is on a weight loss journey after a pregnancy loss. She lost 5 lbs through diet and exercise over 2 months and another 6 just in the past 3 weeks that she’s been on Tirz 2.5mg/wk. only 25lbs to go lol

She loves working out (cycle classes, HIIT circuits, lifting, hikes with her dog, swimming). She’s a vegetarian so it’s hard getting her daily protein in but she is really trying now to hit at least 100g every day.

I have a theory that since she doesn’t eat meat, she’s not getting any L-Carnitine in her regular diet. And I think that makes fat metabolism harder for her body. I’ve ordered some AOD9604 (I know I know) and she’s going to take L-Carnitine with it fasted in the morning, then go on a run with her pup. She will do this for 2 months and report back. Five days on, two days off. She gets the weekends off lol. The theory is, alongside the Tirz, AOD is going to aid in kick starting lipolysis. The L-Carn will help shuttle the free fat to be metabolized for energy. Since she’s working out 2x a day (morning run or hike with pup and a studio class in evening), she’ll need that energy. If she was more sedimentary, she could have taken Lipo-c and avoided the painful IM injection of L-Carn but like I said, I think she actually needs it.

Has anyone else tried this stack and what was your experience? Happy to hear from you!

 

[scarywood75]

So lucky to have found you all! I’ve been silently reading everything for the past two weeks- finally made an account to join the fun. My RS is on a weight loss journey after a pregnancy loss. She lost 5 lbs through diet and exercise over 2 months and another 6 just in the past 3 weeks that she’s been on Tirz 2.5mg/wk. only 25lbs to go lol

She loves working out (cycle classes, HIIT circuits, lifting, hikes with her dog, swimming). She’s a vegetarian so it’s hard getting her daily protein in but she is really trying now to hit at least 100g every day.

I have a theory that since she doesn’t eat meat, she’s not getting any L-Carnitine in her regular diet. And I think that makes fat metabolism harder for her body. I’ve ordered some AOD9604 (I know I know) and she’s going to take L-Carnitine with it fasted in the morning, then go on a run with her pup. She will do this for 2 months and report back. Five days on, two days off. She gets the weekends off lol. The theory is, alongside the Tirz, AOD is going to aid in kick starting lipolysis. The L-Carn will help shuttle the free fat to be metabolized for energy. Since she’s working out 2x a day (morning run or hike with pup and a studio class in evening), she’ll need that energy. If she was more sedimentary, she could have taken Lipo-c and avoided the painful IM injection of L-Carn but like I said, I think she actually needs it.

Has anyone else tried this stack and what was your experience? Happy to hear from you!

I haven't tried that stack, but I appreciate the effort and reasoning you put into this

You can't go wrong with that thinking, good luck!

 

[Calm Logic]

Welcome!

Even vegans should naturally produce enough L-carnitine (at least to prevent deficiency):

Do Vegans Need Carnitine? | Livestrong.com

The best food sources of carnitine are animal products, including meats and dairies, but vegans who strictly avoid these products generally do not get carnitine deficiency.

www.livestrong.com

Generally your body makes sufficient carnitine to meet your daily needs, and your kidneys are quite efficient in conserving carnitine when the level falls. Even with a carnitine-deficient diet, a healthy person rarely has carnitine deficiency.

But popular weight-loss supplements do have L-carnitine, so it may be of some benefit. It seems the jury is still out. But we all have our own preferences and favorite theories. I like B-12 injections even though they may not help much (or even at all since I was always in the normal range). The cost vs. benefit ratio is good enough for me since a vial of B-12 is only $1 from India.

 

[Peloma]

Welcome! Speak freely here. Everyone is an rs since we're all taking our research peptides.

Your stack sounds interesting. Keep posting about it and let us know how it goes.

 

[Pinmebaby1moretime]

I haven't tried that stack, but I appreciate the effort and reasoning you put into this

You can't go wrong with that thinking, good luck!

Thank you so much! And thank you for replying on other posts, I'm learning a lot here!

 

[Pinmebaby1moretime]

Welcome!

Even vegans should naturally produce enough L-carnitine (at least to prevent deficiency):

Do Vegans Need Carnitine? | Livestrong.com

The best food sources of carnitine are animal products, including meats and dairies, but vegans who strictly avoid these products generally do not get carnitine deficiency.

www.livestrong.com

But popular weight-loss supplements do have L-carnitine, so it may be of some benefit. It seems the jury is still out. But we all have our own preferences and favorite theories. I like B-12 injections even though they may not help much (or even at all since I was always in the normal range). The cost vs. benefit ratio is good enough for me since a vial of B-12 is only $1 from India.

Valid point! This makes me feel better for sure, thanks for linking the article. Let's see if the stack has any delta in fat loss!

 

[Pinmebaby1moretime]

Welcome! Speak freely here. Everyone is an rs since we're all taking our research peptides.

Your stack sounds interesting. Keep posting about it and let us know how it goes.

Thank you fellow rs 🙂 Yes, I'll definitely let you all know how it goes- getting the stack from HK peptides.

 

[zpped]

Welcome, I'll just bluntly say AOD and L-carn are both a waste of money. The effect you want only comes from increasing growth hormone. That can be done directly with hgh (illegal) or gh secretougues like tesamorelin/ipamorelin. But these are not something to dabble in without a lot of research into getting your own bloodwork and reading it.

 

[Skidude]

Thank you fellow rs 🙂 Yes, I'll definitely let you all know how it goes- getting the stack from HK peptides.

Welcome, and full disclosure.. I cannot read the 3rd party RS posts without thinking...
"it puts the lotion on it's skin or it gets the hose again.." LOL

Seriously, you will be glad you found this place

 

[zpped]

Welcome, and full disclosure.. I cannot read the 3rd party RS posts without thinking...
"it puts the lotion on it's skin or it gets the hose again.." LOL

Seriously, you will be glad you found this place

And no need to talk that way here. It's not required here. We're all injecting ourselves with Chinese mystery drugs here.

 

[Calm Logic]

The effect you want only comes from increasing growth hormone.

Woah........even GHK-Cu affects like 4,000 genes. So if you add enough of the indirect pathways to weight loss, they could be greater synergistically than one may expect. And "the efficacy of the therapeutical use of GH [growth hormone] to treat obesity is relatively limited."

 

[Calm Logic]

https://www.sciencedirect.com/science/article/abs/pii/S240545772030053X

"L-carnitine supplementation provides a modest reducing effect on body weight, BMI and fat mass, especially among adults with overweight/obesity."

 

[zpped]

https://www.sciencedirect.com/science/article/abs/pii/S240545772030053X

"L-carnitine supplementation provides a modest reducing effect on body weight, BMI and fat mass, especially among adults with overweight/obesity."

Yup. 1.2kg. I'd call that a waste.

 

[Calm Logic]

All the more reason to take more 😀

"A non-linear dose-response association was seen between l-carnitine supplementation and body weight reduction (P < 0.001) suggesting that ingestion of 2000 mg l-carnitine per day provides the maximum effect in adults."

 

[zpped]

All the more reason to take more 😀

"A non-linear dose-response association was seen between l-carnitine supplementation and body weight reduction (P < 0.001) suggesting that ingestion of 2000 mg l-carnitine per day provides the maximum effect in adults."

`This association was not seen for BMI, WC and body fat percent.` ...All the actual important measurements... (well BMI is mostly pointless too)

 

[Calm Logic]

But most supplements have a better risk vs reward compared to HGH:

https://www.mayoclinic.org/healthy-lifestyle/healthy-aging/in-depth/growth-hormone/art-20045735?hl=en-US

Growth hormone - Wikipedia

en.wikipedia.org

Researchers also did not discover any gain in muscle strength, which led them to believe that GH merely let the body store more water in the muscles rather than increase muscle growth. This would explain the increase in lean body mass.

 

[zpped]

But most supplements have a better risk vs reward compared to HGH:

https://www.mayoclinic.org/healthy-lifestyle/healthy-aging/in-depth/growth-hormone/art-20045735?hl=en-US

If you look at my post again, I'm definitely not encouraging anyone to take gh. My point was, stick with the incretin memetics because they are much simpler and proven effective.

 

[Calm Logic]

Of the peptides, do you think tesa or ipamorelin or some combination is best for burning fat?

 

[Peloma]

Of the peptides, do you think tesa or ipamorelin or some combination is best for burning fat?

Let's hope. I have both now, and plan on making a cocktail after the Mots-c.

 

[zpped]

Of the peptides, do you think tesa or ipamorelin or some combination is best for burning fat?

HGH is also a peptide (polypeptide to be very exact), but if you mean the secretagogues Tesa/Ipa are best used in combination. Tesa can be substituted for ModGRF (cjc NO dac). Tesa has more research though. But most people don't use them long enough to see benefits. Elevated IGF1 levels for at least 6 months for it to become apparent. But even with secretagogues you need to be doing regular blood tests to monitor levels.

Let's hope. I have both now, and plan on making a cocktail after the Mots-c.

What is your IGF1 and zscore baseline?

 

[Peloma]

What is your IGF1 and zscore baseline?

260's on Igf1... why do you ask?

 

[Calm Logic]

But most people don't use them long enough to see benefits. Elevated IGF1 levels for at least 6 months for it to become apparent.

That does explain a lot, thanks. I have my money on clenbuterol, partly because I am cheap 🙂

 

[Pinmebaby1moretime]

HGH is also a peptide (polypeptide to be very exact), but if you mean the secretagogues Tesa/Ipa are best used in combination. Tesa can be substituted for ModGRF (cjc NO dac). Tesa has more research though. But most people don't use them long enough to see benefits. Elevated IGF1 levels for at least 6 months for it to become apparent. But even with secretagogues you need to be doing regular blood tests to monitor levels.


What is your IGF1 and zscore baseline?

Tesamorelin activates GHRH receptors in the pituitary gland of the brain, and I previously had a tumor there, it was removed but you can never be too careful. So that’s off the table for me. Actually many people have benign pituitary adenomas and don’t even know! Only relieved after an autopsy of someone dead at 92. Mine just caused other issues which is how I found out. So that’s why I’m trying another stack (AOD+L-Carn+Tirz).

 

[zpped]

260's on Igf1... why do you ask?

You said you're going to use some tesa/ipa right? If you're already at 260, assuming that's a zscore between 1.5-2 for you (i don't know your demographic though) You're unlikely to see a big difference with tesa/ipa. They don't tend to push people over 2 because the other mechanisms of the body start pushing back.

 

[Peloma]

You said you're going to use some tesa/ipa right? If you're already at 260, assuming that's a zscore between 1.5-2 for you (i don't know your demographic though) You're unlikely to see a big difference with tesa/ipa. They don't tend to push people over 2 because the other mechanisms of the body start pushing back.

Gotcha. We'll see. My main concern is reduction in visceral fat and slight muscle development (not a main focus).

I appreciate the info. Hopefully there is an impact. 6'2" 250 (and losing) Hispanic male... in case those demos help.

 

[zpped]

Gotcha. We'll see. My main concern is reduction in visceral fat and slight muscle development (not a main focus).

I appreciate the info. Hopefully there is an impact. 6'2" 250 (and losing) Hispanic male... in case those demos help.

Age and sex are the most important factors for the zscore, but taller people also tend to have higher numbers as well (even though it doesn't factor into the zscore)

The idea of tesa and visceral fat is tied back to it's study on AIDs patients who have abnormal amounts of visceral fat. Most logically it effects all fat equally. Pumping IGF1 up 100 points will have a modest effect, but since yours is already high it would be unusual for you personally to get even half that increase from secretagogues.

 

[Peloma]

Age and sex are the most important factors for the zscore, but taller people also tend to have higher numbers as well (even though it doesn't factor into the zscore)

The idea of tesa and visceral fat is tied back to it's study on AIDs patients who have abnormal amounts of visceral fat. Most logically it effects all fat equally. Pumping IGF1 up 100 points will have a modest effect, but since yours is already high it would be unusual for you personally to get even half that increase from secretagogues.

Late 40s... keep it coming. I like this info.

 

[zpped]

Tesamorelin activates GHRH receptors in the pituitary gland of the brain, and I previously had a tumor there, it was removed but you can never be too careful. So that’s off the table for me. Actually many people have benign pituitary adenomas and don’t even know! Only relieved after an autopsy of someone dead at 92. Mine just caused other issues which is how I found out. So that’s why I’m trying another stack (AOD+L-Carn+Tirz).

Do you know why the research on AOD was abandoned? The receptors that were promising in the mice studies don't exist in humans and the inventor gave up when the human trials had no results. But because it's legal, safe, and cheap to make it has become a favorite of the influencers to make a quick buck.
But like I said, you're just going to be wasting your money.

 

[Modernomeds]

Let's hope. I have both now, and plan on making a cocktail after the Mots-c.

Have you had a chance to try the tesa/ipa combo? I took it for several weeks but I kept getting red and itchy lump where I injected. It would last a few days. Did you have similar reactions?

 

[Peloma]

Have you had a chance to try the tesa/ipa combo? I took it for several weeks but I kept getting red and itchy lump where I injected. It would last a few days. Did you have similar reactions?

I've been taking it for the past 3 days am and pm. No isrs, but my sleep sucks.