Just got Epithalon 10mg kit- am I really supposed to pin these entire vials...?

[lavender]

I want to run a cycle of epithalon and I knew I was ordering these two lots of 10mg, enough for 2 cycles, but now that I'm looking at them it's hit me that I should be pinning an entire one of these nightly? Is this right, am I missing something? Nothing else I've used had had anywhere near this volume, usually a vial of anything lasts me many weeks.

 

[Chili777]

I want to run a cycle of epithalon and I knew I was ordering these two lots of 10mg, enough for 2 cycles, but now that I'm looking at them it's hit me that I should be pinning an entire one of these nightly? Is this right, am I missing something? Nothing else I've used had had anywhere near this volume, usually a vial of anything lasts me many weeks.

Do some searching here. That's the max dose of the older protocol. There is a long Epitalon thread that's fairly recent that will answer your questions. Then you can decide what your best option is.

 

[annessa77]

I want to run a cycle of epithalon and I knew I was ordering these two lots of 10mg, enough for 2 cycles, but now that I'm looking at them it's hit me that I should be pinning an entire one of these nightly? Is this right, am I missing something? Nothing else I've used had had anywhere near this volume, usually a vial of anything lasts me many weeks.

I have been doing 5mg per day and have 3 days left of a 10 day cycle. There is so many different opinions on this one and others. You have to do alot of your own research and find what is truly best for you. This one there is information from 300 mcg to 10mg I even saw one that was 50mg. I decided to go in the middle of the road and see if it works for me. You can also look up different country's protocols on this since there are many that actually use this peptide.

 

[jw717us]

Do some searching here. That's the max dose of the older protocol. There is a long Epitalon thread that's fairly recent that will answer your questions. Then you can decide what your best option is.

That’s the best answer right here!

Follow the science back and understand it. There are some pretty clear explanations out there as to what was done before and why it may not be right today. Unfortunately the Internet saving everything, and some folks just reposting old info as gospel leads to a lot of noise.

 

[Jfrick11]

My experience (note: I started DSIP at the same time and changed ROA) , so this obviously isn’t a controlled experiment😉):

I initially started at 10 mg, sub q, taken about 30 minutes before bed, after what I believed was a reasonable amount of research. I ran that dose for three nights.

The results weren’t great:

• Sleep quality was poor
• Significant next day grogginess
• Mild headache-like feeling
• Overall, not restorative sleep

During that phase, my sleep score averaged around 50.

I then switched to 1 mg/day intranasal, and I’m currently on day 4 of that approach.

The difference has been noticeable.

• I’m not sleeping longer, but I’m waking up far less (maybe once per night vs. 6–7 times previously)
• Deep sleep is up ~25%
• Sleep scores have been 96–99% consistently

This has been some of the best sleep I’ve had in a long time.

Random thoughts....
Lower dosing and intranasal delivery may result in more favorable central nervous system signaling and less spillover into pathways that cause next day sedation or headaches. It’s also possible the higher dose was simply excessive for me. DSIP may be contributing as well.

Takeaway: In my case, more was not better. Lower dose + route of administration mattered far more than I expected.

 

[Chili777]

My experience (note: I started DSIP at the same time and changed ROA) , so this obviously isn’t a controlled experiment😉):

I initially started at 10 mg, sub q, taken about 30 minutes before bed, after what I believed was a reasonable amount of research. I ran that dose for three nights.

The results weren’t great:

• Sleep quality was poor
• Significant next day grogginess
• Mild headache-like feeling
• Overall, not restorative sleep

During that phase, my sleep score averaged around 50.

I then switched to 1 mg/day intranasal, and I’m currently on day 4 of that approach.

The difference has been noticeable.

• I’m not sleeping longer, but I’m waking up far less (maybe once per night vs. 6–7 times previously)
• Deep sleep is up ~25%
• Sleep scores have been 96–99% consistently

This has been some of the best sleep I’ve had in a long time.

Random thoughts....
Lower dosing and intranasal delivery may result in more favorable central nervous system signaling and less spillover into pathways that cause next day sedation or headaches. It’s also possible the higher dose was simply excessive for me. DSIP may be contributing as well.

Takeaway: In my case, more was not better. Lower dose + route of administration mattered far more than I expected.

You illustrate the current school of thought perfectly. It's not that the older protocols are bad or crazy, it's just that they are probably overkill based on what we know now. I always want to know what the minimum effective dose is for any peptide, and then I can decide to adjust it up or down from there, based on my own response.

 

[Jfrick11]

You illustrate the current school of thought perfectly. It's not that the older protocols are bad or crazy, it's just that they are probably overkill based on what we know now. I always want to know what the minimum effective dose is for any peptide, and then I can decide to adjust it up or down from there, based on my own response.

I am a fan of lowest dose possible too.
I wasn't going for full throttle on this one😬, but most everything you pull up says 10mg/day, even the more "reliable" sources.
The effect I was feeling compared to how you're supposed to feel is what led me to dig deeper. Fortunately here, a thread just happened about the questionable mainstream dosing.

 

[Chili777]

I am a fan of lowest dose possible too.
I wasn't going for full throttle on this one😬, but most everything you pull up says 10mg/day, even the more "reliable" sources.
The effect I was feeling compared to how you're supposed to feel is what led me to dig deeper. Fortunately here, a thread just happened about the questionable mainstream dosing.

I use this site as a reference. The peptide information and protocols are updated continuously and it's labor of love for the couple that runs it. https://pep-pedia.org/ They are also open to suggestions, adding new peps and just about anything else.

 

[MsGizmo]

I want to run a cycle of epithalon and I knew I was ordering these two lots of 10mg, enough for 2 cycles, but now that I'm looking at them it's hit me that I should be pinning an entire one of these nightly? Is this right, am I missing something? Nothing else I've used had had anywhere near this volume, usually a vial of anything lasts me many weeks.

I've read that you don't need those large doses to benefit. It seems that the dosage in many of the studies had been mistranslated ... a big failing of using the metric system is that they use mg and ng ... very different amounts but visually look alike and the n and the m keys are right next to each other making typos so easy to make. While I don't think taking the larger doses is dangerous in any way ... I think taking a smaller dose is just fine too. I am personally thinking to take .5mg doses instead of 10mg. So 1 vial will be the entire 20 days.

 

[MsGizmo]

I use this site as a reference. The peptide information and protocols are updated continuously and it's labor of love for the couple that runs it. https://pep-pedia.org/ They are also open to suggestions, adding new peps and just about anything else.

ooo ... nice resource.

 

[Chili777]

ooo ... nice resource.

It's been my go-to. I ran into him on Reddit by happenstance (before my ban). Someone had posted on the main Peptide sub that they had compiled a peptide resource themselves and they were advertising it as free to all.

Apparently, it was a total rip of this site and the owners had tagged their site pages, so they tracked the thief down and called them out there. The guy said his wife, primarily, works really hard on keeping it updated and he helps out. They sound like great members of the pep community and the site is a great resource, and growing.

 

[miss-sanne]

I want to run a cycle of epithalon and I knew I was ordering these two lots of 10mg, enough for 2 cycles, but now that I'm looking at them it's hit me that I should be pinning an entire one of these nightly? Is this right, am I missing something? Nothing else I've used had had anywhere near this volume, usually a vial of anything lasts me many weeks.

i get i t soon and plan on doing 0,5 mg for 20 days. (pep-pedia)

 

[mercutio]

I've read that you don't need those large doses to benefit. It seems that the dosage in many of the studies had been mistranslated ... a big failing of using the metric system is that they use mg and ng ... very different amounts but visually look alike and the n and the m keys are right next to each other making typos so easy to make. While I don't think taking the larger doses is dangerous in any way ... I think taking a smaller dose is just fine too. I am personally thinking to take .5mg doses instead of 10mg. So 1 vial will be the entire 20 days.

It was a translation issue, but not for the units. The natural peptide is Epithalamin and Epitalon requires 1/100th the dose of that.

 

[MsGizmo]

It was a translation issue, but not for the units. The natural peptide is Epithalamin and Epitalon requires 1/100th the dose of that.

Thank you for the correction, all I remembered was that it was a translation issue messing up the recommended dosage.

 

[Chili777]

It was a translation issue, but not for the units. The natural peptide is Epithalamin and Epitalon requires 1/100th the dose of that.

In her Epitalon explanation on Reddit, Anela corrects herself and her math further down in the chat by saying the potency difference is more like 10x, so 10 mg becomes 1 mg, not 100 mcg. I found 1 mg to be very effective. I'm not sure if 100 mcg would be, it might, but given my age and history, I opted for 1 mg. A week after finishing a 20 day cycle, I still feel more clear and alert.