I'll chime in and say that I've been happily enjoying up to 12oz of wine a day (most days just 6oz), using a measure so that I don't go over 'cause the glass is big, counting it in my daily calories, and still losing when I stick to my calorie goals. I was a bit stuck for a couple of months, but I bumped up to 10mg Tirz and I'm losing again now, with the wine. I don't doubt that things would work *even better* if I let it go completely, but I don't want to, and I get along well enough to be okay with the consequences. I just really like a glass of unwinding wine at the end of a day.