Protocol for reducing Tirz and starting Reta?

[Day3cat]

I have been on 7.5 of tirz and would like to add Reta. How should I go about this? Ex: lower Tirz next pin to 5.0 and add 1.0 Reta, then week 2 Tirz 2.5 and Reta 2, etc?

 

[BrightCandle]

Due to the half lives it takes 4 pins or so for the new dose to stabilise so whatever change you make should be more like monthly than weekly. You could try calculating the total but its just a recipe for more sides. The actual ratio could be 2.5 to 1, or it could be more like 1:1, its impossible to know.

Dropping to 5 and adding 1 and sticking for a month seems like a reasonable first step to me. Then you reassess whether that is enough or not and if not add some Reta and repeat, that will give you some idea of the ratio for the next jump. I think slow and steady with knowledge is the right way to go for minimum disruption but there is always just the option of stopping Tirz and moving straight to Reta and starting at 2mg for the first month and being as aggressive as the trials you would likely be back up to dose in 3 months.

 

[alphaskunk65]

Ive seen vendors that market Reta Tirz blends together in the vial. Not sure of the ratios in there. It may help to look at dose calculators to see if they have data for that blend.

 

[BBA1969]

I have been on 7.5 of tirz and would like to add Reta. How should I go about this? Ex: lower Tirz next pin to 5.0 and add 1.0 Reta, then week 2 Tirz 2.5 and Reta 2, etc?

I agree with BrightCandle.

It's not a totally bad plan but you should stay a few weeks on a new dosage to reach steady state and assess if the combo is working for you instead of jumping to new doses every week.

 

[Jrammi]

I went from 15mg Tirz weekly to 10mg Tirz and 5mg Reta weekly. No issues. In a month or two, when my weight drops even further, my intent is to go down to 7.5mg Tirz and 5mg Reta.

 

[janedoe]

My experience, posted previously..... yours may vary.
I was maxed out on 15mg Tirz when I hit goal, after 1 year, 5/25. I dropped the Tirz to 10mg, the following week, then the week following that I went right to Reta, I believe 1 or 1.5 intially, then to 3mg and that's were I stayed. I did stack reta w/ Cagri .250mcg, until 11/25. I dropped the Cagri stack bc I lost 15Lbs after goal weight and didn't want to loose more weight. I've haven't needed to go up on Reta despite some mild food noise, just bc I am easily satisfied and still at a caloric deficit. I don't worry about eating. I prefer to couple some behavior/ lifestyle approaches bc food noise isn't that bothersome to me, due to being easily satisfied in my maintenance. Weight is stable at 3mg 1x per week.

 

[finesse]

Hi, I am new to the forum and I am based in the UK. I have been on mounjaro for a few months, but the cost per month here is out of hand as you move up through the dose ranges. I have been looking at Reta for just over a month now and I am now ready to take the next step

I went from 15mg Tirz weekly to 10mg Tirz and 5mg Reta weekly. No issues. In a month or two, when my weight drops even further, my intent is to go down to 7.5mg Tirz and 5mg Reta.

Any insight into food noise following reduction of triz

 

[MFGamesta]

I did something similar. Since both have about the same half life of 7 days, I just quit cold turkey and went right to reta. Basically 4-week transition just from going cold turkey.