Putting Air in the syringe and into your vial.

[Thighknee]

A laminaire flow hood is not a rocket science. 2 micron hepafilter and carbon filter, 2x 12V pc cooloing fans, 12V speed regulating adapter and a plastic box is all you need. Particles counter, box, hepa and carbon filters are from IKEA. Adapter and fans are from Aliexpress.

It is not for professional use and doesn't have to be more than that. Yes, it can be much easier and cheaper than you can imagine. Reconstituting your vials and filling cartridges in front of it gives you some peace of mind at least. You must use it at an environment free of external air flow and pets. Also sanitise all material you use by spraying them with %70 isopropyl alcohol through an atomiser. %70 is more efficient than %100 because of evoporating speed.

View attachment 28119

Thats an awesome job skaylife well done man! I'll definitely consider making something like this in the next few weeks too, I'm sure it would be worth the effort for that extra bit of security.

 

[CathyGoesFar]

I inject air in the vial. I also don't use an alcohol swab on my skin which the WHO and others agree is unnecessary. No problems.

People treat injections like hobbies and get way into it.

 

[BNLFL]

Yes - initially, no. But as you draw from it, it will create a vacuum. Depends on how much you are drawing.

You just don't listen. I'm only venting when filling a new vial with freshly reconstituted product. I'm not playing with little 10mg vials, I do 50 and 60mg vials. I only push air in when I want to draw from the new Reta vial into my injection syringe. There's zero vacuum or pressure in that new vial.

 

[Birdie]

Yes, it can.

Mainly Pseudomonas bacteria in the air (against which benzyl alcohol has little effect). Staph that shed from your skin, body hair/hair. Possibly a few fungal spores from you and your clothes. Above all, the entire microbiome surrounding you within a radius of about one meter, which you release with every exhalation. Enough? ;-)

That’s why you need to thoroughly disinfect your hands or wear alcohol-treated gloves, remove watches and jewelry, wear a mask (I still have plenty from the COVID...), and work in a clean, windless environment (nowadays, I have to turn off the AC and fans, and with it being 40°C outside, that’s tough!).

Watch nursing training videos to learn best practices.
Definitely avoid random YouTube videos (especially PepCritic; I just watched one, and it made my skin crawl how badly he does it!).
I prepare the recons in batches in pen vials. The venting problems you have don't occur when injecting with a pen. It's really a consequence of the multi-dose in a vial.
I put a hairnet on my head and a non-woven lab coat during recons (not during injections). They're really inexpensive, and you can use them for a while: when you're working alone, there's no risk of cross-contamination. Just, watch out for the cat!

You can use a filter attached to the end of a vent needle to equalize the pressure. This filter can be reused for a while if you store it properly. PTFE is good for air, but PES is okay too. 0.1µm PTFE if you’re really paranoid ;-) Even paranoids can have enemies: Pseudomonas and Staphylococcus are nasty.

Respectfully, this is overkill and not how nurses do things, even as students with an instructor standing over them.

 

[notfatanymore123]

I don't not vent, until I cannot get a good pull. At that time, if that time comes, then I will put in a syringe of air. Most of the time a little air sneaks in when I remove the needle from the stopper.

 

[eidos]

Respectfully, this is overkill and not how nurses do things, even as students with an instructor standing over them.

Sterile eye drops, sterile injectable preparations, and chemotherapy drugs are prepared in hospital pharmacies in cleanrooms that meet at least ISO Class 5 (Class A) standards.

The question was: «Can the air entering the vial contaminate it?» My answer is yes, it can. I’m not saying it will happen every time; no one can say that. There are a few simple precautions we can take at our level that are worth taking.
I take these medications because I have one of the ten deadliest diseases on this planet. I’d be an idiot not to apply the methods I learned in my first career.
Look at what happens to a pot of coffee left in the office over the weekend. I don’t want that under my skin. That’s a space reserved for my chérie.

 

[tcpnomad]

You just don't listen. I'm only venting when filling a new vial with freshly reconstituted product. I'm not playing with little 10mg vials, I do 50 and 60mg vials. I only push air in when I want to draw from the new Reta vial into my injection syringe. There's zero vacuum or pressure in that new vial. View attachment 28420

You are all good. I did read what you have been posting.

What I wrote was in response to what someone else said.

I think this argument has mostly just been a bit of a misunderstanding.