Reconstituted Amopure 30mg Tirz…no stinging, no ISR, effective results

[nonyabizznez]

I have found the consistency of the pucks in Amo Pure to consistently be identical to other lypholized powders. Are you repeating hearsay or providing first hand evidence of what you are saying?

I have product from Arctic (RIP), Skye, Transforma, Eros, Nexha, QSC, SRY and Amopure. Amo's looks different than all of them and I have T,S & C from them... delicate broken pucks (porous, not solid) no biggie, stuff works. They even tell you their product is produced differently, No mannitol. Mine shipped from China via Hialeah FL. (I'm in GA)

Here's a picture from Amopure of what to expect:

 

[Desertteepee2]

The guy who does testing/COAs on the products and tested 30+ vials in August said it. He has a discord. They can tell from the tests (can tell during the purity test based on what it looks like vs. Others)

There's a group currently working on getting a counterion test done.

“the guy”…sounds very official.
Well…as I said previously…the lypholized powder in Amopure, in my RSs experience, is identical to any they have come across be it Pharma Grade Peptides, Peptide Science Peptides or even Amino Amigos. So
I’m basing my statements on actual hands on observation. Not what “the guy” said on discord.

 

[MiniatureSnail]

“the guy”…sounds very official.
Well…as I said previously…the lypholized powder in Amopure, in my RSs experience, is identical to any they have come across be it Pharma Grade Peptides, Peptide Science Peptides or even Amino Amigos. So
I’m basing my statements on actual hands on observation. Not what “the guy” said on discord.

I have found the consistency of the pucks in Amo Pure to consistently be identical to other lypholized powders. Are you repeating hearsay or providing first hand evidence of what you are saying?

I wouldn't call it hearsay, but if you're asking if I myself observed a difference in texture, then no. I've never purchased Amo and if I did, it wouldn't occur to me to open a lyophilized vial and play with the powder.

The guy who owns/runs PeptideTest.com has a discord. Sorry that I don't know his real name. On that discord, he posted a screen shot of a short conversation between himself and someone from the lab where the peptides are tested where the lab tech mentioned how the consistency is different in the Amo vials. I went and found it after this conversation last time and the exact adjectives he used were "fluffy" and "sticky".

Nothing good or bad was otherwise said about the company. Just an objective observation regarding texture/consistency.

I myself am not saying anything good or bad about Amo. Just sharing some information I came across on a different platform. It wasn't meant to influence anyone's opinion. Feel free to ignore it.

 

[Dee X]

I have product from Artic (RIP), Skye, Transforma, Eros, Nexha, QSC, SRS and Amopure. Amo's looks different than all of them and I have T,S & C from them... delicate broken pucks (porous, not solid) no biggie, stuff works. They even tell you their product is produced differently, No mannitol. Mine shipped from China via Hialeah FL. (I'm in GA)

Here's a picture from Amopure of what to expect:

Their R is like that too btw.

 

[Garbo]

bguz1200 said:
Where can I find this info from PeptideTest? Is it from a video, posted here, or other forum?
Thank you for this. I followed every thread here regarding the group test and thought I read every AmoPure post, I guess I missed this one statement from PeptideTest.
Do you have a screenshot? I'm interested in the exact words he used.

No, sorry. Again, it was mentioned in his discord server, not on this forum. I would have to scroll up through months of chatter looking for it. If it comes up again, I'll take note.

I wonder if perhaps the heroic @Cndmk, who somehow managed to herd a bunch of crazed amo-buying cats into a new kind of group test experiment, might have a record of what the test lab said?
Regardless, @Cndmk, you are a legend, and I hope you have recovered from that gesture of good will

 

[clevesand]

If you're not concerned that one manufacturer thinks they're so much smarter than everyone else that has been producing peps for years and really has a better mousetrap that looks like cocaine instead of T and is burning people, please go ahead and order their mad scientist concoction. If it works, it must be ok.

 

[Siesta]

I reached out to Amo today after finishing a 60mg vial…gained 5 lbs over a month while using their Triz. I had stinging and injection site reactions, which has never occurred since starting Triz in January and did not occur when I switched back to my prior compounded Triz this week. I also had a strong reaction (nausea and lethargy) when I switched back to the compounded Triz at the same dose making me think I’d used an underfilled vial from Amo. Amo sent me a COA implying it correlated with my same batch and showed overfilled vials (62.72 mg; 63.46 mg; 61.48 mg; 63.19 mg). Test was ordered on 7/26/24. However, I’d received the Triz in the same timeframe the big group test was occurring which had multiple slightly under filled vials (but not under filled enough to create the symptoms I had this week). My order shipped from Texas. They told me if I had any prolonged burning or stinging to let them know right away…which I’d already done and did in my next email also. Those symptoms were ignored with a response that I could send out for my own testing and if it demonstrated insufficient qty they’d reship. I was not looking for a replacement but rather wanted to just provide feedback to them. I’d already accepted this will be a $1000+ lose. Wonder if the injection site reaction could be related to their product being made with TFA salts? Not sure if that could cause it or not?

 

[Garbo]

If you're not concerned that one manufacturer thinks they're so much smarter than everyone else that has been producing peps for years and really has a better mousetrap that looks like cocaine instead of T and is burning people, please go ahead and order their mad scientist concoction. If it works, it must be ok.

LOL they *are* fluffy white pucks!

I was very happy with my one and only purchase from Amo (back when they were still Amopeptide) but every time I went to reconstitute another one of their vials, I got flashbacks to some *very* wild times in the cocaine-crazy 1980s Miami.

 

[Garbo]

I reached out to Amo today after finishing a 60mg vial…gained 5 lbs over a month while using their Triz. I had stinging and injection site reactions, which has never occurred since starting Triz in January and did not occur when I switched back to my prior compounded Triz this week. I also had a strong reaction (nausea and lethargy) when I switched back to the compounded Triz at the same dose making me think I’d used an underfilled vial from Amo. Amo sent me a COA implying it correlated with my same batch and showed overfilled vials (62.72 mg; 63.46 mg; 61.48 mg; 63.19 mg). Test was ordered on 7/26/24. However, I’d received the Triz in the same timeframe the big group test was occurring which had multiple slightly under filled vials (but not under filled enough to create the symptoms I had this week). My order shipped from Texas. They told me if I had any prolonged burning or stinging to let them know right away…which I’d already done and did in my next email also. Those symptoms were ignored with a response that I could send out for my own testing and if it demonstrated insufficient qty they’d reship. I was not looking for a replacement but rather wanted to just provide feedback to them. I’d already accepted this will be a $1000+ lose. Wonder if the injection site reaction could be related to their product being made with TFA salts? Not sure if that could cause it or not?

Very sorry you are going through this

 

[scarywood75]

Don't forget that our brain is strong, that's why placebo and nocebo are a thing. If it stings, you may think it won't work and that'll cause it to work less for sure.

 

[Cndmk]

bguz1200 said:
Where can I find this info from PeptideTest? Is it from a video, posted here, or other forum?
Thank you for this. I followed every thread here regarding the group test and thought I read every AmoPure post, I guess I missed this one statement from PeptideTest.
Do you have a screenshot? I'm interested in the exact words he used.



I wonder if perhaps the heroic @Cndmk, who somehow managed to herd a bunch of crazed amo-buying cats into a new kind of group test experiment, might have a record of what the test lab said?
Regardless, @Cndmk, you are a legend, and I hope you have recovered from that gesture of good will

Hey there, I'm not sure heroic is the word I would use, maybe lucky it worked out.

Peptide-Test had a lab tech note that the amopure for L30 was a different consistency, and it was more "annoying" to work with, keep in mind you need to read this on the inverse, sorry it's how discord search works (check timestamps).

Hope that helps!

 

[Cndmk]

Let me be very clear, the stinging while it would be nice to point to a specific thing and say "THIS IS IT", I doubt even Amopure would have a direct answer.

I think there was something different between L30 vials and L60 vials, and it's definitely possible that the L30 vials were more prone to stinging based on everyone's statements in this forum as anecdotal evidence. I think though that the whole thing got blown up to a really large "hey Amopure has this huge problem", when in reality it was probably slightly wrong measurement or some kind of manufacturing issue with a small batch of the L30 stuff or an employee was having an off day while making it. It's noted Amopure offered to replace orders affected if the person sent proof of destruction of existing product (what a weird request right?).

Many people measured the pH of their vials in the group test and nothing was off there, so I doubt we will ever know what the exact source of the stinging was.

There is also a lot of "questionable" variables people introduce when reconstituting their peptides, like using some random ass Amazon brand BAC water, or maybe buying really cheap (and are they ACTUALLY sterile?) syringes.

Me personally? I did all my math, and with the testing, Hospira BAC water, Hospira sterile vials to reconstitute to, the kits, filters for reconstituting, and all other medical stuff, I came out to ~$75 per 60mg vial with buying 4 kits AND testing 10% of my vials.

I understand not everyone has the spare cash to splurge on that kind of a stash and the economies of scale in cost you get, but I just don't think it's worth it to save 20-30 bucks on some no-name syringes or no-name BAC water. If we were talking working gloves and not an injectable compound I'm putting into my body, we can have a different conversation.

 

[Cndmk]

I reached out to Amo today after finishing a 60mg vial…gained 5 lbs over a month while using their Triz. I had stinging and injection site reactions, which has never occurred since starting Triz in January and did not occur when I switched back to my prior compounded Triz this week. I also had a strong reaction (nausea and lethargy) when I switched back to the compounded Triz at the same dose making me think I’d used an underfilled vial from Amo. Amo sent me a COA implying it correlated with my same batch and showed overfilled vials (62.72 mg; 63.46 mg; 61.48 mg; 63.19 mg). Test was ordered on 7/26/24. However, I’d received the Triz in the same timeframe the big group test was occurring which had multiple slightly under filled vials (but not under filled enough to create the symptoms I had this week). My order shipped from Texas. They told me if I had any prolonged burning or stinging to let them know right away…which I’d already done and did in my next email also. Those symptoms were ignored with a response that I could send out for my own testing and if it demonstrated insufficient qty they’d reship. I was not looking for a replacement but rather wanted to just provide feedback to them. I’d already accepted this will be a $1000+ lose. Wonder if the injection site reaction could be related to their product being made with TFA salts? Not sure if that could cause it or not?

I would say that +/- 5% of fill is not really an underfill for the representative sample, and care MUCH more about the purity of the product (which I think the lowest was like 98.9%, and it was 1 vial maybe out of 22 or something, most were in the 99.5% range.

I have been using my AmoPure stash for 2 months now with no change vs. compounded, I treat each vial as 60mg, regardless of the 1 or 2 mg our test showed it was lower by. Natural variation is normal in manufacturing processes, and I wouldn't be surprised at all if most compounding have a range of +/- 2-4% variations in fills.

You can also mix 2 vials together to most likely get closer the representative sample if you get it tested.

There are many independent tests YOU can do to see if your body chemistry is playing a role in how you are feeling, take a few weeks off of all tirz and start back at 2.5mg.

You may also have a unique reaction (stinging) to the medication based on a specific chemical in their fillers that others don't actually experience.

For example, I ordered the "Pegasus" formula from Kimera because I heard good things about the energy benefits because I was experiencing some lethargy on my 7.5mg dose of Tirz. Guess what? Crazy stinging, painful site reaction, and not much energy benefit.... My significant other? No stinging, definitely felt some energy benefit. Does that mean that was a bad product, or does it mean my body doesn't play kindly with that formulation, seems to be the latter...

 

[bguz1200]

Hey there, I'm not sure heroic is the word I would use, maybe lucky it worked out.

Peptide-Test had a lab tech note that the amopure for L30 was a different consistency, and it was more "annoying" to work with, keep in mind you need to read this on the inverse, sorry it's how discord search works (check timestamps).

View attachment 3105

Hope that helps!

This is exactly what I was looking for! Thank you so much for getting back to me and thank you for organizing that massive group testing!

 

[Garbo]

Hey there, I'm not sure heroic is the word I would use, maybe lucky it worked out.

Peptide-Test had a lab tech note that the amopure for L30 was a different consistency, and it was more "annoying" to work with, keep in mind you need to read this on the inverse, sorry it's how discord search works (check timestamps).

View attachment 3105

Hope that helps!

You're the best, thanks!

 

[nurseratchit]

I have found the consistency of the pucks in Amo Pure to consistently be identical to other lypholized powders. Are you repeating hearsay or providing first hand evidence of what you are saying?

I was in the Peptide Test group test for this is the quote “their lyophilized powder across all of those products has a different texture than any of the other GLP-1s that we test. It is fluffy and sticky instead of being a firm “puck”.

Does this mean anything bad? We don't know. Purity and mass results tested well. It failed sterility but so have other vendors. Lots of people seem to be doing just fine with it but there does seem to be more reports of ISRs and unusual pucks from users who have experience with other research peps and no history of ISRs. It is just a point of curiosity.

I will still use mine and continue seeking more info.

 

[nurseratchit]

I have product from Arctic (RIP), Skye, Transforma, Eros, Nexha, QSC, SRY and Amopure. Amo's looks different than all of them and I have T,S & C from them... delicate broken pucks (porous, not solid) no biggie, stuff works. They even tell you their product is produced differently, No mannitol. Mine shipped from China via Hialeah FL. (I'm in GA)

Here's a picture from Amopure of what to expect:

They have told @MingHenry that are now using mannitol...we don't know what they were using before. But the vendors also say a lot of things to move product which is why we test.

 

[nurseratchit]

“the guy”…sounds very official.
Well…as I said previously…the lypholized powder in Amopure, in my RSs experience, is identical to any they have come across be it Pharma Grade Peptides, Peptide Science Peptides or even Amino Amigos. So
I’m basing my statements on actual hands on observation. Not what “the guy” said on discord.

That is great that it works for you; other users have different experiences that are also valid. My pucks look good but I have not reconstituted them yet. No one is saying it's a bad product; there is just a curiosity about why they seem to be getting a rep for their ISRs.

 

[nonyabizznez]

They have told @MingHenry that are now using mannitol...we don't know what they were using before. But the vendors also say a lot of things to move product which is why we test.

I get that somewhat. I've seen lots of Amopure tested on purity and sterility, none on mystery ingredient (if that's even feasible). I was commenting on the pucks appearance and efficacy.

 

[Vicki]

I want to add back into the conversation.

I contacted amopure about my ISR and they offered either a refund if I return the product or a replacement if I destroy it.

Customer service was very nice and offered this with no questions/issue.

I chose to do the replacement so they told me to break the vials with a hammer and send pictures. They said the new batch will be ready in 5 days and will ship to me. I'll keep everyone posted with updates