SS-31 + MOTs-C vs NAD+

[Gohengrin]

They're synergistic. Prime with SS-31 to repair mitochondria and then stack MOTS-C and NAD+.

I did that protocol, but felt absolute no energy from it. Tired as always.

 

[Jellybelly54]

IM is usually my go-to to avoid ISRs. Worked great for me with glutathione from China (and some testosterone in a cheap oil). Diluting the glutathione with more BAC helped a lot too. But haven't tried MOTS yet.

Should I be nervous about going IM on something that causes this much ISR?

 

[CNCCurrency]

Wondering how many running MOTS have skin reactions? After about the 3 rd shot I’ve developed significant injection site reactions. Almost like a Brute Enforcer Emeritus sting with raised, extremely itching , red bump that stays for days. I guess from what i have read that this is common. I don’t know if I can keep running this with these reactions. I had the same thing happen with KLOW . Wondering if I have a significant IgE allergy tendency ? Maybe I’ll try some steroid cream and benedryl topical at the injection site next time. I’m afraid to go IM and have an anaphylactic reaction? I’ve switched BAC water and I’m filtering the pep and maintaining aseptic technique for reconstitution btw.

I do, goes away after a few days. I do it on my thighs now and it's not as bad.

 

[Calm Logic]

Should I be nervous about going IM on something that causes this much ISR?

Do you have an extra vial or a larger vial to dilute this stuff? Usually IM can handle larger volumes like even 2+ mL, so you can dilute like crazy if you want.

Another option is to just try a smaller amount of your current concentration by IM, to be more careful, to compensate for not diluting further.

And I don't know about pH and all that with MOTS. So pH testing may be another option.

 

[Jellybelly54]

Do you have an extra vial or a larger vial to dilute this stuff? Usually IM can handle larger volumes like even 2+ mL, so you can dilute like crazy if you want.

Another option is to just try a smaller amount of your current concentration by IM, to be more careful, to compensate for not diluting further.

And I don't know about pH and all that with MOTS. So pH testing may be another option.

I could try diluting and IM I guess. Wondering if I should have an epi pen on standby though? Maybe next I’ll do a benedryl, Zyrtec, topical roid and Benadryl topical before injection. These injection sites itch SO BAD! Ugg

 

[Calm Logic]

If it is that bad, I would just resell it on B/S/T, haha.

But not a bad idea with oral Benadryl. I don't know about the creams before injection.

 

[gantou]

Wondering how many running MOTS have skin reactions? After about the 3 rd shot I’ve developed significant injection site reactions. Almost like a Brute Enforcer Emeritus sting with raised, extremely itching , red bump that stays for days. I guess from what i have read that this is common. I don’t know if I can keep running this with these reactions. I had the same thing happen with KLOW . Wondering if I have a significant IgE allergy tendency ? Maybe I’ll try some steroid cream and benedryl topical at the injection site next time. I’m afraid to go IM and have an anaphylactic reaction? I’ve switched BAC water and I’m filtering the pep and maintaining aseptic technique for reconstitution btw.

Mots isn't too bad for me. How much bac did you use to reconstitute? Sometimes diluting it more can help. I like to use 3ml of bac for Mots-C. For me NAD is the one in this stack that gets me, even if the PH is good I still get bruised when I inject it.

 

[Jellybelly54]

Mots isn't too bad for me. How much bac did you use to reconstitute? Sometimes diluting it more can help. I like to use 3ml of bac for Mots-C. For me NAD is the one in this stack that gets me, even if the PH is good I still get bruised when I inject it.

Only used 2mL and injected 2.5mg so a really big dose. Maybe I will decrease the dose, dilute, pretreat and cross my fingers

 

[Cdub100]

The burn mean it's working 😛

 

[Twowheelr2]

How often can you run the SS31/MOTS-C/NAD cycle? Do you need to take the SS31 again on subsequent cycles?

I'm waiting on some deliveries and I'll be running my first cycle of this pretty soon. Definitely excited to try it out.

The protocol I’m following is a 14 week cycle.

I pin a lot of of peptides. I rotate all over my whole midsection.

i did begin a GLOW cycle while running the NAD+, SS-31, MOTSc protocol. 3rd pin today. First pin in my glute, 2nd & 3rd abdomen. Not too bad at all. Best was 1/2 pin in abdomen followed by vibe gun. I think my timing will work out to finish up about 25 daily 2mg GLOW doses before the MOTSc begins in the protocol.

 

[Such1943]

Week 6 in the books. I've got roughly 2 days of SS-31 remaining and plan to start Most-C for an overlap. The initial 6 weeks have been excellent. The recent discussions about PIP from Most-C sounds fun, I haven't experienced much PIP from anything I've tried so far. NAD+ 150mg, Mots-C 5mg M/W/F in the morning until all vials are gone.

The burn mean it's working 😛

 

[jmon1977]

Wondering how many running MOTS have skin reactions? After about the 3 rd shot I’ve developed significant injection site reactions. Almost like a Brute Enforcer Emeritus sting with raised, extremely itching , red bump that stays for days. I guess from what i have read that this is common. I don’t know if I can keep running this with these reactions. I had the same thing happen with KLOW . Wondering if I have a significant IgE allergy tendency ? Maybe I’ll try some steroid cream and benedryl topical at the injection site next time. I’m afraid to go IM and have an anaphylactic reaction? I’ve switched BAC water and I’m filtering the pep and maintaining aseptic technique for reconstitution btw.

This is fairly common. I get the same type of reaction with MOTS-C and KLOW/GLOW, but it isn't debilitating or anything. It doesn't seem to be anything to be concerned with other than the annoyance.

 

[Twowheelr2]

Week 6 in the books. I've got roughly 2 days of SS-31 remaining and plan to start Most-C for an overlap. The initial 6 weeks have been excellent. The recent discussions about PIP from Most-C sounds fun, I haven't experienced much PIP from anything I've tried so far. NAD+ 150mg, Mots-C 5mg M/W/F in the morning until all vials are gone.

Right behind you. Must be a different protocol but the same peptides. I’m on 4mg SS-31 daily and NAD+ twice a week. After the SS-31 cycle it’s M/W/F MOTSc at 5mg per. Haven’t heard about the pinging from MOTSc until now. Let me know how you tolerate it. I was so concerned about GLOW and KLOW, I prepped a vial and have been testing it for ISRs. 6 pins and not bad at all.

 

[Twowheelr2]

4 week update on running SS31 with some background:
Late 30s, I’ve been on low dose Reta (0.5mg e5d) for 4 months. No other peps or meds, except a cycle of glow50. Dropped 9% body fat, now around 19%. Took nad+ e3d 50mg and felt significant change in baseline energy. Finished a cycle of ss-31 4mg every day for last 25 days and I’m left with more energy than I can spend. I don’t remember the last time I went to bed without being tired, but still being able to sleep. My head is buzzing in the morning when I wake up. Sleep score is averaging 88 despite getting up at least once to pee at night. I’m going to start mots-c before workouts next week but honestly don’t even feel the need for it. I can stack 2 workouts in a day and not get tired. Recovery is better too. Didn’t even know I could raise my baseline energy levels this high.

Happy to answer any questions and help other level up 💪

Rereading your post from Dec. How is the protocol going? I’m on the 14 week mitochondria protocol and in the middle of the SS-31 section. I also have noticed more endurance. Don’t seem to have higher levels of energy, but don’t tire out during workouts or chores. Would appreciate a follow-up of your experience.

 

[Celestar62]

Rereading your post from Dec. How is the protocol going? I’m on the 14 week mitochondria protocol and in the middle of the SS-31 section. I also have noticed more endurance. Don’t seem to have higher levels of energy, but don’t tire out during workouts or chores. Would appreciate a follow-up of your experience.

I have the same experience using a combo of Nad+, 5-Amino, and Mot-C 3x a week.

 

[Calm Logic]

I definitely will not be trying MOTS-c. A friend of mine just had an anaphylactic reaction to MOTS including tongue swelling and some throat swelling. Benadryl helped and it subsided. But between the ISR issues of others and now this, not worth it.

 

[Twowheelr2]

I definitely will not be trying MOTS-c. A friend of mine just had an anaphylactic reaction to MOTS including tongue swelling and some throat swelling. Benadryl helped and it subsided. But between the ISR issues of others and now this, not worth it.

Do you know what kind of dose your friend took?

 

[CNCCurrency]

I definitely will not be trying MOTS-c. A friend of mine just had an anaphylactic reaction to MOTS including tongue swelling and some throat swelling. Benadryl helped and it subsided. But between the ISR issues of others and now this, not worth it.

I have only heard of it happening with im, and the only reason was because it hit a vein and went straight in the blood. Never sub q

 

[Calm Logic]

I have only heard of it happening with im, and the only reason was because it hit a vein and went straight in the blood. Never sub q

You are right, that is what happened. 5 mg by IM.

Of course, the whole reason for IM usually with MOTS-c is ISRs. So you can't win for losing. But obviously an ISR is better than risking dying.

 

[Jellybelly54]

MOTS-C is scary. I’v SQ’d and IM’d it and they both suck. The more you use it the greater the reaction. I shot some into my quad and although I didn’t have anaphylaxis an area in my quad swelled to the sized of a tennis ball . Serious pain , swelling and itching for days. I’ll sell someone my 2 pucks of 10 if anyone is interested . I wanted it to work but that’s part of research I guess. You have to know when the subject is in danger and terminate the experiment before the worst outcome. For real, DM me if you want to purchase any!

 

[SakeSan]

Rereading your post from Dec. How is the protocol going? I’m on the 14 week mitochondria protocol and in the middle of the SS-31 section. I also have noticed more endurance. Don’t seem to have higher levels of energy, but don’t tire out during workouts or chores. Would appreciate a follow-up of your experience.

I quit motsC halfway through. I had more energy than I could expend in a day and my sleep was suffering. Unsure if it was MotsC but it was the easier one to drop for me. Still have the baseline energy uptick from ss31 and continued nad+. Funny thing I realize is that our brains get accustomed to the changes in baseline fairly quickly. I don’t necessarily “feel” the higher baseline but haven’t felt tired in weeks so I know it’s there.

 

[jmon1977]

Have any of you that are getting really bad reactions with large doses (5 mg) tried microdosing? VigorousSteve on YT is an advocate for running smaller doses more frequently, even daily.

 

[Jellybelly54]

Have any of you that are getting really bad reactions with large doses (5 mg) tried microdosing? VigorousSteve on YT is an advocate for running smaller doses more frequently, even daily.

I got reactions from mixrodoses as well