Thinking about switching to Sema from Reta

[HappyBear]

Might want to look into Cagri along with Reta instead of Sema. I haven't tried it myself since my Tirz x Reta stack is working well, but I've seen people say it kicks ass.

Whar does you stack look like of tirz and reta? Have you benefitted with both? How far apart do you take them? Im looking to do the same.

 

[Throwfa]

Whar does you stack look like of tirz and reta? Have you benefitted with both? How far apart do you take them? Im looking to do the same.

After running with 2.5mg of tirz for a few months I started getting some food noise again. Instead of upping the dose I decided to add 1mg of reta to see what would happen. Had some lying around and figured why the hell not.

I'm currently on 2.5mg tirz + 2mg of reta. I track my rhr with a health tracker and definitely saw the reta get into action when upping the dose to 2mg.

So far so good, can recommend. More people have been running it successfully.

 

[HereKittyKitty]

I'm a big fan of Sema. Started on it and did well with minimal sides (unlike a lot of anecdotal chatter). It is a solid offering. Just because it is an older formula doesn't mean it is without value.

 

[AngieHolmes]

Last Wednesday I stacked Sema with my typical Reta to help with food noise.

I was thinking with my high level of Reta exposure without sides I would take .25mg 2x/week. The last couple days I’ve felt rather bleh, especially yesterday evening. Bleh enough that I skipped my typical Reta dose last night waiting for the feeling to pass. The most and longest duration of bleh I’ve had by far in 26.5 weeks on this GLP ride.

I’m undecided what my plan is. It’s not a regular dose of Reta and .25mg of Sema, I’m sure of that. Maybe a step down on my Reta and .125mg of Sema. Maybe normal Reta and no Sema. Maybe something with Reta and a splash of Tirz. Maybe get back to normal on regular Reta alone and decide from there. Maybe Cagri instead of Sema or Tirz. All kinds of options.

Reta + Tirz has a lot of anecdata behind it. Works for me : )

Of course you'll have to fool around to find the right dosages for you. Good luck!

 

[woundcarping]

Reta + Tirz has a lot of anecdata behind it. Works for me : )

Of course you'll have to fool around to find the right dosages for you. Good luck!

I'd never tried Sema, so part of the draw was that novelty. I started on Tirz back in December with no meaningful sides.

I may try .125mg of sema 2x weekly, or maybe switch to Tirz, or maybe I'm ok not stacking, or maybe cagri, or Elora if/when I get some (lets be honest, I'll probably get "some.")

 

[AngieHolmes]

Staying flexible and collecting data on your own experience is the way.

 

[BikesOverCars]

My bad. Wasn’t hating on Sema although I did say Tirz is superior which is maybe a stretch since I haven’t tried it. Tirz is definitely more readily available however just from looking at pricelists.

 

[J.Ayden]

The semaglutide hate that comes up in these threads makes me really sad lol. And kind of defensive? which I know doesn't make any sense because obviously it's nothing personal, but it's kind of like when a bunch of people shit talk your favorite band or something.

As other people have said, sema is good for stacking if you want to go that route because it's the only single GLP agonist so stacking it will hopefully cause less side effects from over activating a bunch of pathways at the same time, if that makes sense.

Also semaglutide is much cheaper than the rest -- I don't understand why people claim it's not. You can pretty easily find a 30mg kit for less than $120. Each vial would last ~3 months if you did the highest prescribed dose. An equivalent kit (in terms of top dose) of tirze would be 240mg, which doesn't appear to be readily available. So let's compare tirze 60 instead, which a lot of vendors carry. It ranges in price from $150 (usually a sale) to $250 to even more, although I'd say mid 200 seems to be the average. Each vial would only last a month at the highest dose. The price difference is stark.

That difference is actually why, I believe, a lot of vendors don't seem to offer sema as much anymore -- a lot of people have switched to newer offerings, or just never tried it, plus it costs so little that there's not a huge benefit for vendors to stock it. Why would they, when they can only reasonably charge ~$60 for a 10mg kit that would last 40 weeks, vs selling a 60mg kit of tirze that lasts the same amount of time but costs 3-4 times that amount?