I time mine this way too!! Friday and Saturday are my eat more days and a dinner out makes that happen soooo easily
Tirz 2.5 dosage experience
- Thread starter onepotatotwopotato
- Start date
onepotatotwopotato
New_Member
Before tirz I'd binge a lot on sweet stuff and would get randomly sleepy in the afternoons. I wonder if that was blood sugar related?
Vacation4us
Registered
I wore a CGM the first 2 weeks when I started. I am 100% sure my BS kept me fat before GLP’s and after it was no more fat storage machine. It’s not just decreased appetite and slow digestion. I still have an appetite and eat. I eat less but BS levels play a huge role in fat burning or fat storing. They just don’t get talked about enough IMHO.
Nikki nik
Research Enthusiast
Excited about
I wondered the same....Why are people super responders? I actually was wondering if I am because I've never really taken medicine at all. Maybe for a headache a few times a year. Nothing daily. Could that be the reason some are? Just a thought. Versus someone that takes daily meds of some sort. I don't know.
I noticed when I first started with Saxenda, liraglutide, that some days it was hard to eat much and the weight loss would slow, then I would eat a lot for a couple days and then drop a couple pounds. I think it turns food noise off but it also helps keep your metabolism revved up. Whatever was wrong with me metabolically was “fixed” through the Glp-1. I think just listening to your body goes a long way with this stuff..
Nikki nik
Research Enthusiast
Very trueI noticed when I first started with Saxenda, liraglutide, that some days it was hard to eat much and the weight loss would slow, then I would eat a lot for a couple days and then drop a couple pounds. I think it turns food noise off but it also helps keep your metabolism revved up. Whatever was wrong with me metabolically was “fixed” through the Glp-1. I think just listening to your body goes a long way with this stuff..
Means research subject
YoYoFat
Registered
Research Subject.
ellebeejay
New_Member
I take daily meds and supplements, I've done my share of recreational drugs (older and wiser now, don't do drugs, kids!)...and I'm a super responder. I "super respond" to many drugs, from OTC to prescribed, so I'm not shocked about this one but I'm pretty grateful!
Nikki nik
Research Enthusiast
Likewise!!!!!! I've had my share of this and that. Glad to hear you're wiser now and life is great on this side!
YoYoFat
Registered
My RS is the same. RS used to be on low dose Ritalin, both extended and immediate release, and any other very low dose drug produces significant results. As I understand it, this could be because RS’s gut health is pretty good, allowing for quick absorption and processing of drugs, hormones, peptides, etc.
2.5 still going strong with my RS, and I sure hope for $$$ reasons that it stays that way!
Nikki nik
Research Enthusiast
Yes this! Definitely I understand money reasons.. Here at maintenance trying to figure out the cheapest maintenance
My rs had their third 2.5 injection Sunday and has no appetite suppression still. They ate a sandwich an hour ago and are hungry again, which has been the story of their life. They can eat and then be hungry a half hour later
I think they’ll do their next dose of 2.5 next Sunday then go to 2.5 Sunday and 2.5 again Thursday and see how that goes for them
I think they’ll do their next dose of 2.5 next Sunday then go to 2.5 Sunday and 2.5 again Thursday and see how that goes for them
I'm curious to know what causes a "super responder" to be so successful at lower doses like 2.5. I started losing 1.5-2lb right away, not sure if I can call myself a super responder or what.
It's not necessarily the starting weight, since the highest the starting weight, the faster/bigger losses at first. In my case, my SW was close to 190lb and I still had considerable losses. Someone at 300lb will definitely lose a lot at first (eve if it's just "water weight" or inflammation)
Maybe it's the comorbidities, like PCOS, hormonal issues or glucose/insulin issues like pre-diabetes insulin resistance, etc.
Maybe it's how strong is the appetite suppression and food aversion? In my case that's a huge factor. I'm truly not hungry and I force myself to eat 800-1000 calories a day.
I know I'm lucky that I respond so well to 2.5 mg and I'm planning on staying at this dose for as long as I can.
It's not necessarily the starting weight, since the highest the starting weight, the faster/bigger losses at first. In my case, my SW was close to 190lb and I still had considerable losses. Someone at 300lb will definitely lose a lot at first (eve if it's just "water weight" or inflammation)
Maybe it's the comorbidities, like PCOS, hormonal issues or glucose/insulin issues like pre-diabetes insulin resistance, etc.
Maybe it's how strong is the appetite suppression and food aversion? In my case that's a huge factor. I'm truly not hungry and I force myself to eat 800-1000 calories a day.
I know I'm lucky that I respond so well to 2.5 mg and I'm planning on staying at this dose for as long as I can.
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I have wondered the same. There must be something else going on that the peptide clears up for some and others don’t have that issue or something
I definitely had a super responder experience at 2.5 to the point i had an anxiety attack at how little i was eating the first week lol. so much of my research has folks confident that you wont see any effects until 5.0 gives the wrong impression even if it is statistically significant.
ive spent my whole life eating huge meals and then still being hungry and now i have to work to eat a banana and a cup of coffee. the tirz might work immediately but my brain is gonna take some time to adjust
ive spent my whole life eating huge meals and then still being hungry and now i have to work to eat a banana and a cup of coffee. the tirz might work immediately but my brain is gonna take some time to adjust
nurseratchit
Research Enthusiast
Everyone’s results will vary. I know some people who have lost all their weight never going over 5mg. And I know of others who have gone as high as 30 mg. I think some people titrate up too much too soon because they’re not getting results fast enough. Also, it’s normal to have fluctuations in ‘feels’. Some days you may still get hungry; it doesn’t mean the med isn’t working. We are supposed to get hungry; it’s just that we don’t always recognize true hunger signals in our modern, food everywhere society.
Also, as the newness wears off, people may feel they have a developed a tolerance rather than realizing this is their new normal. I remember how mind-blowing my first dose was with the near-immediate shut off of food noise and it was like, “is this how ‘normal’ people feel?!” Now I’m just used to it. Consider yourself lucky and think of all the $$ you’re saving being a super-responder!
onepotatotwopotato
New_Member
Are any other super responders neurodivergent? Self diagnosed or otherwise
RS does feel hungry sometimes but is starting with small portions and finding it is plenty.
RS does feel hungry sometimes but is starting with small portions and finding it is plenty.
Lazerteeth1
New_Member
I often wondered that too. RS is responding VERY well on lower doses and doesn't feel the fatigue other people feel because RS is already fatigued with life as it is.
jennster
New_Member
I feel this so much. The fatigue hasn't changed a whole lot sometimes. Maybe the day after the shot but at this point not even then. But if anything I feel more motivated I guess because I feel better about things and a better headspace.
