Wellbutrin+naltrexone

diogenes

GLP-1 Novice
Member Since
Jul 3, 2025
Posts
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From
Berkeley, CA
I've had good luck with Reta, stabilizing at 8mg/week. In 4 months:
  • BMI 33.5 → 29.2
  • LDL 135 → 102
  • A1C 5.6 → 5.0
  • BP 135/95 → 125/85 (both with medication)
  • TSH 4.6 → 3.7
All of which is great. But my relationship to food is still unhealthy. When I'm stressed, I still eat sugary bullshit compulsively—just less of it. I want to change that.

It seems my overeating/sugar addiction is part of an overall motivation problem. I'm prone to distraction, procrastination, and difficulty managing energy levels. I've often been called ADHD, hypomanic, etc. I think food problems are a sub-problem of that.

I don't want to try tesofensine because the aggression/moodiness and cardiac symptoms scare me. I've heard that wellbutrin+naltrexone can reduce cravings and is itself effective for weight loss. Does anyone have thoughts on this combo?
 
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