What dose of reta are you at?

I am in my fourth month on Reta, and currently doing 3.5 1x per week. 4-4.5 is probably closer to ideal though. I'm at the end of a vial, and the last shot will be 4. I'll move to 4.5 if that doesn't seem to be adequate. I took 5 a couple of weeks ago, and that was too much. There is definitely a learning curve to this stuff. I went from dosing every other day to once a week in about a two week period, and really had to rethink and rework EVERYTHING.
 
TRS123 said:
The fact that it is subtle loss of muscle makes it hard to recognize it is happening. I was never muscle-y either but average strength from physical work. After a year I know I’m not as strong when I working and my thigh muscle get stained quickly when carry things up a set of steps. My arm strength and muscle mass is down quite a bit
My suggestion is slow down the amount of weight you loose per month. I was dropping several pounds a week early on
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Yes. 16.8 in 4 weeks is 4.2 per week. I was reading that anything over a pound per week is likely muscle. I think I only have another month on 2mg and then I will titrate down.
 
390120 said:
I know everyone is different but I read a lot of posts where people start at low doses and don't need to titrate up that high of a dose.
I'm curious as to if people go all the way up to 12mg like in the clinical trials, if if they have reaped most benefits at lower doses.

So my question is:
How long have you been taking Reta for?
Where along are you in your journey?
What is your current dosage?
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I'm at 3 mg.
 
Im on 5mg going to 6 mg this week. Pin every 6 days and gym 4-5 days a week. I’m down 63 lbs. SW was 270 and today was 207. Goal is 190 to go into healthy BMI I’m also doing Cagrilintide 1.5mg per week for food noise.
 
I am on 2.5 MG weekly. I titrated up from .5 ,.75, 1 and up weekly. Most people don’t do it this why and I don’t necessarily think it’s better in anyway it’s just what I did. I’ve lost 15 pounds so far and it has been amazing! My goal is to get down to 200 lbs. started at 232 woke up 217 this morning. I have only felt sides once and it was when I first pinned 2.5mg but it only lasted 1 day.
 
I started on Jan 20th and am taking 1mg every 5 days. I lost 4 lbs so far, so I'll stay here as I don't have much to lose. I definitely go from being hungry, to getting full fast, to having food aversions - all in the same day, so reta is doing things, but it's not like my wife who is on tirz who can barely eat (and all she does is sleep). MUCH prefer having a normal life w/ reta
 
6 weeks in, 17lbs down.

Started at 1mg for 4 weeks, now 2mg for last two. Will continue at 2mg for two more weeks, then move to 3mg.

No sides other than crappy sleep, which is a concern with moving up in dosage.
 
I fucked up this week cz i was distracted while injecting, i think i took like 5mg when i should be at 3, feeling like shit rn 🙁
 
I am currently on 5mg Tirz (every 5 days), so effectively 7mg/week and I am looking to switch over to Reta. Here is my plan. Drop Tirz to 4.0mg and add 0.5mg reta. After a couple of weeks drop Tirz to 3.0mg and bump up reta to 1.0mg. See how I feel and go from there.

Do you see any flaws my thinking / plan?
 
80s.diver said:
I am currently on 5mg Tirz (every 5 days), so effectively 7mg/week and I am looking to switch over to Reta. Here is my plan. Drop Tirz to 4.0mg and add 0.5mg reta. After a couple of weeks drop Tirz to 3.0mg and bump up reta to 1.0mg. See how I feel and go from there.

Do you see any flaws my thinking / plan?
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You know you better.

I’ve had very little to no adverse sides on Tirz. I started Tirz on 12/12 and was taking 2.5mg of Tirz 2x weekly when I started the bridge to Reta on 1/10 with my last regular Tirz 2.5mg being on 1/8.

I took numerous small doses watching for sides. I’ve taken 17 doses of Reta ranging from 1-4mg totaling 44mg. I’m steady at 2x 4mg Reta now. I took 2.5mg of tirz on 1/14 and 2mg on 1/21 to manage food noise during the bridge.

I had cold sensitivity that wasn’t an objectionable intensity during the bridge… no adverse sides.
 
Just wrapping up week 8 on Reta. Started at 2mg for the first month, and last 4 weeks I’ve been on 4mg. Definitely feeling more hunger this past week or two as my body is getting used to the medication. My wife has been on the same trajectory and feeling similarly so I’m thinking we both move to 6mg week 9 and see how that feels.
 
woundcarping said:
You know you better.

I’ve had very little to no adverse sides on Tirz. I started Tirz on 12/12 and was taking 2.5mg of Tirz 2x weekly when I started the bridge to Reta on 1/10 with my last regular Tirz 2.5mg being on 1/8.

I took numerous small doses watching for sides. I’ve taken 17 doses of Reta ranging from 1-4mg totaling 44mg. I’m steady at 2x 4mg Reta now. I took 2.5mg of tirz on 1/14 and 2mg on 1/21 to manage food noise during the bridge.

I had cold sensitivity that wasn’t an objectionable intensity during the bridge… no adverse sides.
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Thanks for that information, much appreciated.
 
I find it very interesting the real world doses people are taking. I'm surprised people are seeing results as doses below 1mg, maybe it's BMI related?

Anyway to answer the question I started at a BMI of 33.4. 274.4lbs. Previously never tried a GLP1 due to cost. Jumped right into Retatrutide. Due to weight, height, and other factors I started at 2.5mg every 7 days. I just started week 5. I just increased dosing to 4mg. I'm currently at a BMI of 30.9. 253.8lbs. Down 20.6lbs

I can honestly say for the first time in my life I feel like I'm in control of my eating habits. Dropping the food noise has been a really, almost emotional, life change.

This all started after a serious consult with my new P.A.-C. I was suggested to start Tirzepatide and told to consider if I could honestly afford $100 per week to receive it directly from E.L. My insurance denied Tirzepatide coverage, my health care provider said they would outright refuse to prescribe compounded GLP1's as they aren't FDA approved.

Down the rabbit hole I went. My wife and I both are over weight. We had a serious conversation about the risks vs benefits. I bought a single vial Retatrutide 30mg as it looked the most promising, the results we have been seeing don't track daily (fluctuations), but show weekly (consistant loss). I have no regrets.
 
How long have you been taking Reta for?

5 months

Where along are you in your journey?
Had many months of stall on tirz after losing 70+ lbs over 1year or so. I Titrated up slow. No benefits on the scale until got to 6mg ( on Halloween) although it was changing my shape.

Lost 27lbs on reta so far. Would like to lose another 30lbs. Main thing I learned from my tirz journey is stay as low as you can for as long as it’s working when you have a lot of weight to lose ( I didn’t with tirz I titrated up when recommended to do so by provider) so that’s my plan with Reta.

Likely will need reta for life or switch back to tirz for maintenance when/if I get there.

What is your current dosage?

7mg once a week
 
I started at .5mg twice a week for two weeks just to make sure I wasn’t going to have any major adverse reactions or side effects. Absolutely nothing happened. Then moved up to 1mg once a week, and got some results and manageable sides the first week, but then only had the side effects and no results the next two weeks, so doing 1.5 this week and will stay here for at least the next four weeks. I don’t have a lot to lose and work out regularly.

From my perspective, results are a half a pound a week and not being so eager to eat sugar, and side effects are acid burps and mild to moderate fatigue.
 
HidingInPlainView said:
I find it very interesting the real world doses people are taking. I'm surprised people are seeing results as doses below 1mg, maybe it's BMI related?

Anyway to answer the question I started at a BMI of 33.4. 274.4lbs. Previously never tried a GLP1 due to cost. Jumped right into Retatrutide. Due to weight, height, and other factors I started at 2.5mg every 7 days. I just started week 5. I just increased dosing to 4mg. I'm currently at a BMI of 30.9. 253.8lbs. Down 20.6lbs

I can honestly say for the first time in my life I feel like I'm in control of my eating habits. Dropping the food noise has been a really, almost emotional, life change.

This all started after a serious consult with my new P.A.-C. I was suggested to start Tirzepatide and told to consider if I could honestly afford $100 per week to receive it directly from E.L. My insurance denied Tirzepatide coverage, my health care provider said they would outright refuse to prescribe compounded GLP1's as they aren't FDA approved.

Down the rabbit hole I went. My wife and I both are over weight. We had a serious conversation about the risks vs benefits. I bought a single vial Retatrutide 30mg as it looked the most promising, the results we have been seeing don't track daily (fluctuations), but show weekly (consistant loss). I have no regrets.
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Every body is different. Some super repsonders can lose a lot of weight even below the lowest doses from clinical trials and will lose 30-40% of their starting weight, while others stuggle to lose 15% at maximum dose.
 
Valyra said:
1mg, started yesterday! Already no food cravings and I feel full after drinking a little bit. Kinda have to force myself right now to get it down lol
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Wow, I'm still on Tirz but Reta genuinely seems like the next generation peptide here. On Tirz it took me like 2 weeks to get to the point where I didn't feel like eating.
 
AlexSilver said:
Week 9, I am now on 1mg every 3 days. Due to the half life, this maintains approx a 3mg saturation.
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Im on my 5th week.
I weigh then I pin.
Week 1 2mg starting weight 140.9 kg
Week 2 2mg weight 137.2kg
Week 3 2.5mg weight 136.1kg
Week 4 2.5mg weight 134kg
Week 5 3mg weight 130.5kg

Total weight lost after 4 weeks 10.5kgs
 
I started with 1 mg, but titrated up too fast. Currently I am at 2,5 mg, but will go down to 1,5 or 2 mg. I don't have any side effects, but I hate that I don't have any appetite at all, so I have to force myself to eat. I have huge problems to get to my protein intake goal because I'm full from a portion that wouldn't be a starter before Reta
 
I started on Reta on 10/4/2025 and am at 6 mg. I am down 63 lbs. and doing well with the dosage. I use L.E.D lowest effective dose and have no plans to increase my dosage unless and until I hit a wall.
 
Went up too fast. My first 1.5mg dose from yesterday morning hit me this evening like a full on bout of food poisoning. Backing off to 1mg 2x a week. I can’t fathom that the current plan upon FDA approval is to start people at 2mg.
 
Been on Reta for five months now, and am currently pinning 9mg/week, and have been on this dose for the past couple weeks.
 
ropa13ico said:
Been on Reta for five months now, and am currently pinning 9mg/week, and have been on this dose for the past couple weeks.
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Have you noticed much of a difference between the lower dose below 4mg and the higher does where the additional glucagon burn is said to kick in ,
 
Nopenada said:
Went up too fast. My first 1.5mg dose from yesterday morning hit me this evening like a full on bout of food poisoning. Backing off to 1mg 2x a week. I can’t fathom that the current plan upon FDA approval is to start people at 2mg.
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From just a 0.5mg increase?
 
I'm on 10mg a week, and just starting to see appetite control with it. For me, not as effective as Triz was. But also less constipation and nausea than what I had with Triz. Will max out at 12mg, but don't think it's going to make much of a difference.
 
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