Thanks- it was all on Reta, tried Sema and Tirz last year.
What's the Best GLP-1 to purchase that has the least Side effects
- Thread starter Sunrise208
- Start date
To say that it’s super individualized is an understatement. I took brand name Ozempic for 5 months and lost no weight while feeling like complete garbage for the whole 5 months. Then I switched to grey market tirz for 4 months and felt better but didn’t lose any weight until I added phentermine for appetite suppression.
I stopped the tirz because it wasn’t working and switched to Contrave over some blood pressure concerns. I had crazy side effects to contrave AND gained weight on it so I decided to order some Reta and use up the last bottle of tirz that I ordered last year just to get back into the swing of things. For some bizarre reason, I’m having fantastic appetite suppression without phentermine on this bottle of tirz; it only starts to wear off on day 6/7.
Now a month later I have 400mg of Reta in hand and I’m wishing I had ordered tirz instead because I’m down 5lbs this month. So here’s to hoping that Reta works well for me and I don’t need to keep my appointment with my doc next month to get more phentermine.
I stopped the tirz because it wasn’t working and switched to Contrave over some blood pressure concerns. I had crazy side effects to contrave AND gained weight on it so I decided to order some Reta and use up the last bottle of tirz that I ordered last year just to get back into the swing of things. For some bizarre reason, I’m having fantastic appetite suppression without phentermine on this bottle of tirz; it only starts to wear off on day 6/7.
Now a month later I have 400mg of Reta in hand and I’m wishing I had ordered tirz instead because I’m down 5lbs this month. So here’s to hoping that Reta works well for me and I don’t need to keep my appointment with my doc next month to get more phentermine.
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AreYouSureorNo
New Member
I'm brand new to all of this so please forgive my ignorance. I'm on my 2nd week of tirz & have had zero side effects. Is that typical? Thanks in advance for any info
Lots of people have no (or minimal) side effects. I had a little bit of constipation but I resolved it pretty easily by upping my fiber intake and drinking more water. (Both of which I needed to do anyway, really.) Also a bit of a resting heart rate increase, but not a ton. Larger increase on reta.
Some people have very little side effects, some have a ton. Some people respond very strongly immediately, some people need to titrate up. Keep an eye on what you eat and the scale. You may need to go up, or you may react well to a small dose and lose weight without side effects. Go slow and see what happens. If there isn't much difference by your fourth week, go up in dose.
I started with sema and had zero side effects with the minimum dose and all the benefits. I eventually moved to every 5-6 days instead of 7, then half the minimum dose 2-3 times a week based on how I felt. The benefit of grey is you're completely in control of your doses and schedule. Smaller doses more frequently makes me have the benefits with almost no side effects at all.
Just noticed that as well. TIL that's a thing.
Do they just fall off? Come off in the shower? Do they bleed?Just noticed that as well. TIL that's a thing.
No idea, just noticed the few I had are no longer there. Maybe they went out for a pack of cigarettes...
YoYoFat
Senior Member
Anyone noticed a change in their blood pressure from Tirz? Either higher or lower?
I have major white coat syndrome and my home device isn't the most reliable, so curious what y'all have experienced.
I have major white coat syndrome and my home device isn't the most reliable, so curious what y'all have experienced.
DwightTheDelight
Registered
Major blood pressure drop within a month of starting, but in my case it took me from the danger zone to completely normal and it's stayed there ever since.
I've gone from 160/100 (before I started taking max dosage of Losartan) to 95/60 without any BP meds over my 145 lb weightloss journey this year.
I was on two bp meds when I started. Dropped one completely, second is dosage cut in half. Doctor thinks I'll be off it completely in the next couple of months.
When I got put on them, I was told there was 0 chance of ever coming off, even if I lost weight because they thought it was mainly genetic factors at play. Happy to prove them wrong there
YoYoFat
Senior Member
Can I ask how much weight you lost before you came off one of your meds?
I had 40 to lose, and was consistently elevated, sometimes Stage 1 on a white coat day. Before I gained that weight, I was consistently "normal" or even low.
So from like 20 on, I'd go to the doctor and they'd always say "your bp is high" and I'd be like yeah I've heard that and we'd move on. Nobody ever seemed to make it an issue or take the conversation further, so I didn't stress it.
Late last year I was experiencing some extreme anxiety, sweating, mind racing, panic, nausea, almost 24/7 and it kept ramping up. Went to the dr in like December and my blood pressure was very extreme, they contemplated sending me straight to the er. Got put on Hydrochlorothiazide and lisnopril. Both combined got everything under control and I was great.
Started tirz in june at 5 foot 10 283lbs male. I've responded insanely well and melted basically, and by September I was already around 235 and noticed I had been getting very light headed standing up randomly. Finally had a virtual appointment, dr said let's cut the hydros and see how you respond, it's probably too much meds. I was reading kinda low, that brought it back up to normal. Middle of November I started feeling the same, and checked bp and was kind of low again. Dr. cut the lisonpril from 40mg to 20mg and that's where I'm at now.
I've responded so well to tirz, I've been slowing my weight loss since October and trying to have some weeks where I'm over calories in protein (fuck that's a struggle on these meds lmao) to try to keep my strength/muscle at the gym. I was losing 15+lbs a month until I slowed it down myself lol. But was 212 when we cut the lisnopril to 20mg, and im currently right at 200. Hoping to cut it out completely by the time I get to 175ish around march-ish
Hell yeah
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HOLY FUCK god damn impressive as hell
DwightTheDelight
Registered
Incredible results, you two! Could either of you let me know the name of the app you are using please?
Libra
AreYouSureorNo
New Member
Thank you for your help!
