Lots of people have no (or minimal) side effects. I had a little bit of constipation but I resolved it pretty easily by upping my fiber intake and drinking more water. (Both of which I needed to do anyway, really.) Also a bit of a resting heart rate increase, but not a ton. Larger increase on reta.
For me, I started on Sema and got headaches and nausea. Waited a month before I moved to Tirz. Started at 2.5 and never looked back. Interested in Reta as well but haven't tried it.
For me, I started on Sema and got headaches and nausea. Waited a month before I moved to Tirz. Started at 2.5 and never looked back. Interested in Reta as well but haven't tried it.
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