With all the UGLs, there will never be an issue buying Tirzepatide -- depending on if you want UGLs or want to pay for Pharma Pens or buy from like Peptide Sciences or one of the research websites (there could be a shortage there). So far as combo's, I am on 10mg of Tirzepatide but added 2.5mg of Cagrilintide. Both from UGLs (so much cheaper). I have never used Semaglutide due to all of the side effects friends have reported alongside reading some of the issues people have on various boards.
But I have found adding the 2.5mg of Cagrilintide is the sweet spot - during my cycles it is hard to eat so this combo is short (2-3 weeks cutting at max; however, the half life is up to 195 hours, on top of Tirzepatide being roughly 5 days (each of us is different). They help cut body fat percent FAST (for me). These hormones have really improved my overall health at the ancient age of 33... LOL.
Nonetheless, hope everyone reaches their goals and maintains phenomenal health. Just sharing my experience.