Phase 1 study for Eloralintide and Terzepitide

[yeddie]

David W at his blog has a new post about Eli Lilly releasing preliminary results for Eloralintide combined with Terzepitide. As expected it looks promising.

Eloralintide + Tirzepatide = Bariatric Surgery results!​

(Yes, he's a fan.)

This is what Novo thought CagriSema could do.
These are short trials and in no way was there a weight plateau in any arm. This isn’t even the max potential weight loss with this combination. That being said I have a genuine concern that this weight loss is too rapid. Perhaps this is why Lilly has Enlighten-6 which combines eloralintide plus either semaglutide or tirzepatide AFTER you’ve stalled out on weight loss on either of those two agents first.

 

[Scorpio73]

Nice!. are these actually new 2026 human data?

I've only seen the published 2025 eloralintide monotherapy results. Where did these combination numbers come from?

Are these from a conference abstract, a Lilly poster, an investor deck, or something else? I'd love to read the original source if anyone has a link.

 

[Countyroad233]

love this, thank you

 

[leokitcat]

Holy heck that’s some incredible weight loss! In the reta p3 trial is took 104 weeks to get to 30% weight loss compared to 32 weeks or so with tirz+elora

 

[HouseCat]

Thanks for posting this - I am PSYCHED!!! And can’t wait til my Elora comes in later this summer.

 

[Enyola]

Nice!. are these actually new 2026 human data?

I've only seen the published 2025 eloralintide monotherapy results. Where did these combination numbers come from?

Are these from a conference abstract, a Lilly poster, an investor deck, or something else? I'd love to read the original source if anyone has a link.

It's in the article:
"that’s what I found today, when I was looking at the abstracts for the upcoming EASD 2026 (European Association for the Study of Diabetes) conference." (no direct link though, probably not public yet).