Cagrilintide sides: Anyone have advice?

LaughingDuck

LaughingDuck

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Well, I started Cagrilintide 48 hours ago and have quite the nausea effect. Oh, I mean it works, its hard to get 1,500 calories because I'm not into food; nausea isn't helping either. FYI I did 0.250mg, really dumb for thinking I could start at 1mg (don't!),

I was just wondering if anyone on here has had similar sides like me and if they've countered them with something. Also do sides usually go away if your body is used to it.
 
I started as well this week. No I'll effects from the .25 and actually felt a bit hungry a few days in so dosed up again at .25 on Tuesday. I am also on a 1.5 sema dose.
 
didn't have much nausea but the appetite was low. i took electrolytes via liquid iv, also a daily sublingual b12 and daily calcium + vit d. a little fatigue but not bad on days 2-4
 
LaughingDuck said:
Well, I started Cagrilintide 48 hours ago and have quite the nausea effect. Oh, I mean it works, its hard to get 1,500 calories because I'm not into food; nausea isn't helping either. FYI I did 0.250mg, really dumb for thinking I could start at 1mg (don't!),

I was just wondering if anyone on here has had similar sides like me and if they've countered them with something. Also do sides usually go away if your body is used to it.
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Can I ask where did you get it from? I am embarrassed to say that I got mine from Amo about two months ago because they had it in the US and I was impatient. I have felt nothing from the Cagri on day 5 of Tirz starting at .25, .5 and now 1mg. Either this med isn't for me, or this is garbage product from Amo. I did not test.
 
clevesand said:
Can I ask where did you get it from? I am embarrassed to say that I got mine from Amo about two months ago because they had it in the US and I was impatient. I have felt nothing from the Cagri on day 5 of Tirz starting at .25, .5 and now 1mg. Either this med isn't for me, or this is garbage product from Amo. I did not test.
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don't be THAT embarrassed because i got mine from sry. 5mg x 10 vials for $130...good price except for the possible lacing with deadly opioids good luck me
 
clevesand said:
Can I ask where did you get it from? I am embarrassed to say that I got mine from Amo about two months ago because they had it in the US and I was impatient. I have felt nothing from the Cagri on day 5 of Tirz starting at .25, .5 and now 1mg. Either this med isn't for me, or this is garbage product from Amo. I did not test.
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It's np, got it via nexaph
 
LaughingDuck said:
Well, I started Cagrilintide 48 hours ago and have quite the nausea effect. Oh, I mean it works, its hard to get 1,500 calories because I'm not into food; nausea isn't helping either. FYI I did 0.250mg, really dumb for thinking I could start at 1mg (don't!),

I was just wondering if anyone on here has had similar sides like me and if they've countered them with something. Also do sides usually go away if your body is used to it.
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Thank you for this. When I start I will definitely start at .125.
 
electrolytes i'd say. but if nausea continues you can ask your doc for zofran. tell them you're on compounded glp1 and experiencing nausea, or if you are on tirz or sema from a compounder, ask them for zofran.
 
Took .5mg this week split. Really didn't feel anything out side of being a bit tired. I'm broken though, haha.
 
The nausea I could have dealt with. It was the way the fatigue hit and knocked me down like a dead horse. I would def start lower and build up.
 
I think I'm just a sensitive boy and need to be more serious on fiber and electrolytes. Been having stomach issues since starting; at least nausea has mostly gone away just mild stomach ach, thirst and very minor heartburn.


I also will start spreading meals out because I used to only eat twice and I think they might be too big (since glp's reduce the speed of food being processed).
 
LaughingDuck said:
I also will start spreading meals out because I used to only eat twice and I think they might be too big (since glp's reduce the speed of food being processed).
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That’s the direction I have gone as well as not eating 3-4 hrs before bedtime. My body eventually adjusted to the sides but I had to take interim steps to manage them.
 
I was a non responder at the low doses until I hit .75, but when it hit me it hit me hard. I vomited multiple times at that dose and couldn't eat at all for a couple days. If I could offer any advice to the non responders it would be to take it slow and keep in mind this drug had a long half life, so it will take a while to fully kick in.
 
One week update: The first 5 days was bad nausea, stomach discomfort and flu like state at .250mg dose. It was really annoying but worked so good that I was struggling to keep my daily calories in check especially the protein. I did a weigh in on the day I took it and in the week I dropped 10lbs. Ofc some of it is water weight from water so i'll keep you all updated.

This time I took .125mg dose and so far has given slight light headed feeling but nothing too bad.
 
Wow
LaughingDuck said:
One week update: The first 5 days was bad nausea, stomach discomfort and flu like state at .250mg dose. It was really annoying but worked so good that I was struggling to keep my daily calories in check especially the protein. I did a weigh in on the day I took it and in the week I dropped 10lbs. Ofc some of it is water weight from water so i'll keep you all updated.

This time I took .125mg dose and so far has given slight light headed feeling but nothing too bad.
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Wow!!!
 
Thanks for letting us follow along in yall's journey!

I took my first dose (.33mg) on Monday morning, I had some fullness that afternoon. But yesterday I had good appetite suppressant and minor today. I too consider myself a non-respondent. Sema didn't do anything for me and tirz had minimum effects at 15mg, so I'm hoping this does the trick before trying reta.
I got some MOTS-C, mostly just incase the fatigue sets in but it would do good for some extra energy.
 
Good to hear the Nexaph cagri is working. I have a kit that I am setting aside for future use, possibly in tandem with Reta. For my nausea due to Sema, I've found that my food choices are as important as keeping hydrated with electrolytes. I have to limit my meals to one or two sides at most. So oatmeal for breakfast, chicken breast for lunch, etc. And in my case, definitely no eating in the 3 hours before sleep.
 
I split it to 0.125 between two days and didn't have sides. All normal mostly.

Will try a single dose next time.
 
Next week I’ll do the .33mg again. The following week, I’ll consider increasing. I only have a single vial of it for now. I didn’t want 10 vials if I didn’t respond but so far so good. At the end of the month I’ll consider a kit, likely from Nexaph too.
 
Started my Cagri and it’s been working great for me no side effects apart from being tired the day after then I’m totally fine with pretty good suppressant. I stack with my Tirz that I take Sunday then on Thursday I dose my Cagri 0.25 both from SRY, which btw doesn’t have deadly opiates in it since they’re manufactured in totally separate facilities & I get tested for opiates bi weekly… just saying! lol
 
I'm at 7.5mg dose of Tirz and .25 of Cagri did nothing. I did .5 the very next day and had a noticeable appetite suppression effect with no nausea or other side effects. I might step it up to .75 mg Cagri next week if I start getting noticeably hungrier.
 
clevesand said:
Can I ask where did you get it from? I am embarrassed to say that I got mine from Amo about two months ago because they had it in the US and I was impatient. I have felt nothing from the Cagri on day 5 of Tirz starting at .25, .5 and now 1mg. Either this med isn't for me, or this is garbage product from Amo. I did not test.
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Amo Cagri from that period has been anecdotally reported as working by many of people.

What has your entire titration schedule looked like? What dosages are you doing and when?
 
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Whoa, 1 mg. Tell us more. Any nausea? How's the fatigue or other side effects?

I really hate the tiredness from some of these peptides, it's kind of a huge bummer in spite of the huge benefits. And it's pushing me into a whole world of other peptides to fix the SE's of the initial peptides...
 
Dee X said:
Amo Cagri from that period has been anecdotally reported as working by many of people.

What has your entire titration schedule looked like? What dosages are you doing and when?
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Just heads-up/FYI: Amo Cagri rc'vd last week (Nov. 7) + working as expected. no PH issues. This week was first Amo jab, prev. was Skye Peptides (highly rated/trusted, top source). Am doing Amo Tirz (7.5 mg total wkly after titrating up since June) and Cagri (.6mg after titrating up since August, now Amo), weekly w/split dosing of Tirz. Effective, with losses continuing (down 58lbs) since June.
 
hotdog! said:
Whoa, 1 mg. Tell us more. Any nausea? How's the fatigue or other side effects?

I really hate the tiredness from some of these peptides, it's kind of a huge bummer in spite of the huge benefits. And it's pushing me into a whole world of other peptides to fix the SE's of the initial peptides...
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Felt nothing at .25. Felt tired the first day on .5mg. Supringly enough, wasn't tired with the 1mg. Could be my body getting used to it. Had very good supression to the point a protein bar made me feel nauseous the next day. That wore off after a day or two. Then back to eating normal.

I've had an interesting time with cagri. Still cant figure out if it's worth it for me
 
nccane said:
Felt nothing at .25. Felt tired the first day on .5mg. Supringly enough, wasn't tired with the 1mg. Could be my body getting used to it. Had very good supression to the point a protein bar made me feel nauseous the next day. That wore off after a day or two. Then back to eating normal.

I've had an interesting time with cagri. Still cant figure out if it's worth it for me
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i am starting to think that i should have just adjusted my tirz schedule to every 5 days instead of supplementing with cagri. it knocks me on my ass for 2 days and kills my appetite for 2 days, i'm not sure it's a good trade.

but now i have 10 vials of 5mg cagri which is going to take me awhile to get through at 0.25 and 0.5 per week haha.

i've seen a couple people on reddit who said they accidentally started at a higher dose of cagri and then when they went back to a normal dose it didn't seem to work. somebody just posted there that they accidentally started at 2.5mg instead of 0.25. i hope they are ok.
 
hotdog! said:
I'm at 7.5mg dose of Tirz and .25 of Cagri did nothing. I did .5 the very next day and had a noticeable appetite suppression effect with no nausea or other side effects. I might step it up to .75 mg Cagri next week if I start getting noticeably hungrier.
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I just reviewed my log and I was wrong, evidently I started at .1 which was what felt like nothing. Then did .25 the next day and felt good appetite suppression. So I guess a .3 to .5 dose is the sweet spot for me so far.
 
clevesand said:
Can I ask where did you get it from? I am embarrassed to say that I got mine from Amo about two months ago because they had it in the US and I was impatient. I have felt nothing from the Cagri on day 5 of Tirz starting at .25, .5 and now 1mg. Either this med isn't for me, or this is garbage product from Amo. I did not test.
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I tend to discount personal claims that a product either works or does not work to prove that a manufacturer's product is defective or not. That's what testing if for.
 
LaughingDuck said:
This week I had almost no side effects

Weighed today, - 4 pounds where two weeks it was 0, then - 1. That means I'm about 15 pounds total down.

Right now my stack is: Monday = 0.5mg Cagrlintide, Thursday = Trizpetide 5mg
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Does the half mg last a whole week?
 
Peevee said:
Does the half mg last a whole week?
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So someone has a chart on how it's best to do two shots spaced through the week to curb your appetite in a better fashion so I do

0.5 MG Cagri Monday / Trizpetide 5mg Thursday works for me
 
LaughingDuck said:
So someone has a chart on how it's best to do two shots spaced through the week to curb your appetite in a better fashion so I do

0.5 MG Cagri Monday / Trizpetide 5mg Thursday works for me
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Thanks, I’m just starting to research cagri. I do my tirz 2x a week already so it’s no big deal to do the cagri on a similar schedule. I’ll start with .25mg
 
i wouldn't start with 0.25mg twice a week at first. some people get the fatigue and some people don't seem to, but if you get it, it is rough
 
AnnSolo771 said:
Just heads-up/FYI: Amo Cagri rc'vd last week (Nov. 7) + working as expected. no PH issues. This week was first Amo jab, prev. was Skye Peptides (highly rated/trusted, top source). Am doing Amo Tirz (7.5 mg total wkly after titrating up since June) and Cagri (.6mg after titrating up since August, now Amo), weekly w/split dosing of Tirz. Effective, with losses continuing (down 58lbs) since June.
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i got some skye coming tom. i cant wait to try it! super nice dude on the dms from skye also.
how long after mixing the cagri can you inject it? like overnight or hours?
 
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