Luvinhim
New Member
I switched from Sema to Reta and absolutely love it minimum side effects and broke a stall and consistently losing weekly
QSC Retatrutide
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KYRivianMan
GLP-1 Member
*This is not medical advice. Just sharing a few bits of info that I had found. Do with it what you will.
The studies I have read concerning Reta stated test participants lost higher percentage of weight starting at 4 mg dosage/4wks and titrating up to 6mg/4weeks then settling at 8mg for six months. Those who started at 2mg the 4mg etc lost approximately 4% less in that same six months.
Those who stalled prior to 6 months were then put in second half of the study titrating up to 10mg. Many continued safe weight loss for the remaining 6 months while 18% were titrated to a max dose of 12mg. Total in second round study loss on average 28%.
The studies I have read concerning Reta stated test participants lost higher percentage of weight starting at 4 mg dosage/4wks and titrating up to 6mg/4weeks then settling at 8mg for six months. Those who started at 2mg the 4mg etc lost approximately 4% less in that same six months.
Those who stalled prior to 6 months were then put in second half of the study titrating up to 10mg. Many continued safe weight loss for the remaining 6 months while 18% were titrated to a max dose of 12mg. Total in second round study loss on average 28%.
KYRivianMan
GLP-1 Member
I lowered my Tirz dose to 5 mg (from 10mg) and then 48-72 hours later added 4mg of Reta….my results the past two weeks have been the best of my journey thus far.
Arac-attack
New Member
Nice result-BUT no batch numbers
That's old ones, the new batchs of 2024 have color of tops mentionned in the lab reports, along with the picture of the sample, check the price list, click on the name of the item and you will be able to open the lab report
dionysos
GLP-1 Specialist
Thank you Tracy, for the updated 25-072024 Price List.
It is just as you say, the newest batches of GLP1 product do indeed have batch color-top-coded identification.
Also Important To Note: Batch COAs consistently measure FULL TO OVERFULL.
QSC has Good Control of their QA process, and, QSC is committed to providing Good Value to Buyers.
I acknowledge you and Quingdao Sigma Chemical for a continuing improvement in Quality Assurance of your peptide products.
As Buyers we see it, and we appreciate it.
Dennis
It is just as you say, the newest batches of GLP1 product do indeed have batch color-top-coded identification.
Also Important To Note: Batch COAs consistently measure FULL TO OVERFULL.
QSC has Good Control of their QA process, and, QSC is committed to providing Good Value to Buyers.
I acknowledge you and Quingdao Sigma Chemical for a continuing improvement in Quality Assurance of your peptide products.
As Buyers we see it, and we appreciate it.
Dennis
steve789385
New Member
Very interested in the GB of the 10mg Reta that is going on right now. the 97.xx% purity number kind of alarms me. I guess I just haven't seen many 97's in all the Janoshik reports I've looked at for peptides. Anybody have thoughts on that? I guess I'm not sure what the 97% really MEANS as far as what you're getting.
Pharmgirl63
New Member
I would be interested if your heart rate goes up. If you wear a watch that tracks your heart rate you may notice an increase.
dionysos
GLP-1 Specialist
@steve789385
The COA 97% purity means this is NOT "Pharmaceutical Grade"
as generally defined by the US Pharmacopeia (USP) or FDA.
The term is used to define not only the substance itself
but also the manufacturing process.
Complicating matters further, the term is applied
by the FDA only to Approved Drugs which excludes most peptides.
In my NON-MEDICAL PROFESSIONAL opinion
you should not buy this, certainly don't inject it,
and QSC should not be offering this for sale.
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steve789385
New Member
Maybe Tracy will follow up here. Thanks for your insight...definitely seemed an outlier from their other testing.
urSinsn2me
New Member
I'm so glad that I decided to stick with my underdosed 99% pure amo reta over that overdosed 96% and 97% purity from qsc. Bullet dodged
urSinsn2me
New Member
I just check their updated price list which now includes link to test for Sema 5mg, which wasn't previously included there, purity on average some 98.7% is little bit disappointing, but amount above 6mg is very good, some 20% overfill!
I think anything >98% is still OK, especially when overfill so much, but 94-96% for other products - its already really low, QSC should do something about it very fast ...
I think anything >98% is still OK, especially when overfill so much, but 94-96% for other products - its already really low, QSC should do something about it very fast ...
Yes, my resting heart rate increased when I titrated up to 8mg a week in March (reta 8mg is current dose). However, I started testosterone replacement therapy (trt) in December and my HR also increased, but seemed to drop back down a bit before titrating up on Reta 8mg.
My HR was mid to low 50 bpm before TRT, high 50s to 60 before starting 8mg Tirz in March, and now mid to high 60s. Based on that information, I would say Reta probably resulted a higher resting HR. My trt dosage has not changed.
urSinsn2me
New Member
Sure 98% is good but at this point if their other stuff is between 94%-97% why even risk it. From what I've read this company gas had many shots. As I've said before I'll stick to Amos underdosing knowing it's 99%
dionysos
GLP-1 Specialist
@urSinsn2me @milos @peteyb786 @Broken Chef
Just posted this in the Public Square and requested that Zippity Pin It.
Perhaps you should repost your messages there, or, continue your convo on that Warning thread?
I'll be updating the Original Post as I learn more from you and others about it.
Thanks, Dennis
Just posted this in the Public Square and requested that Zippity Pin It.
Perhaps you should repost your messages there, or, continue your convo on that Warning thread?
I'll be updating the Original Post as I learn more from you and others about it.
Thanks, Dennis
dionysos
GLP-1 Specialist
I'm trying not to smirk while also trying to be compassionate @urSinsn2me !
I bought and am using AmoPeptide 99% Reta as well.
Eli Lilly research pen was tested at 95% 😃😃. 95% is apparently clinical trial grade
dionysos
GLP-1 Specialist
@Deeubee
• I'm not in a clinical trial.
• I did not agree to accept higher risk to further medical knowledge.
• It is clearly within Quingdao Sigma Chemical's ability to achieve the highest pharma standards.
I will not accept a Purity level less than "pharmaceutical grade" for peptides that my wife and I use.
I communicate with hundreds of new and prospective peptide users every month, and,
it would be irresponsible of me to suggest that they accept a low grade of drug.
I recommend that NO ONE ACCEPT LESS THAN 99% "pharmaceutical grade" products.
dionysos
GLP-1 Specialist
@Deubee Please pimp and troll elsewhere.
You are using adolescent wit to degrade adult discussion of a serious subject.
That's not welcomed here.
Regarding the discussion of purity figures on the qsc reta batches, @Qingdao Sigma recently shared that their peptide chef didn’t account for pH of some peptide batches which was causing premature degradation. My assumption is that that is responsible for the lower-than-typical purity in those tests, so would hold off on buying until they brew another batch. I like Qsc but their habit of selling through bad batches means it might be a moment to pause any orders whilst they unload all the stuff the new guy cooked in q2.
dionysos
GLP-1 Specialist
I agree that "pausing any orders" while they sell off carelessly cooked batches is
good advice @exploitedworkerbee
Whether or not lower Purity is actually dangerous is above my pay grade.
HOWEVER, it does certainly indicate a lack of due care.
Quingdao Sigma Chemical should not be rewarded for that!
Yeah I don’t think it’s dangerous. As I see it the issue is that, because of the nature of this problem, it’s unclear at this time how much additional degradation will occur between now and when you’re ready to use the peptides, so you don’t know what you’re buying.
a good explanation. I would just add, my personal threshold is more to 98% (same as peppys), yes, we are looking for >99% but if >98% I would not trash out the product, just be cautious post-administration - look for adverse reactions, because the remaining 2% can be anything...
you see, the issue in pharmaceutical/medical field is, it cant depend on "I don't think it's dangerous", this field is evidence-based and we are talking about our health
Neither trolling nor anything.
There is no unified mark. I as just stating fact. An Eli Lilly Reta sample was tested and it was 95% surely they wouldn't be testing therapeutic doses with bunk?
its just definition of ASC grade, nothing more, and ASC grade is not the highest one, that one is USP, so if something is only ASC its telling you you can (maybe) use it but its a lower grade compared to USP
but if you want to use peptides with 95% go ahead, just you should do some reading around, when some people report injection side reactions when using (most probably) not so pure products
dionysos
GLP-1 Specialist
No, it is not just me.
The United States Pharmacopeia, the National Formulary and the FDA have a few things to say as well.
The United States Pharmacopeia, the National Formulary and the FDA have a few things to say as well.
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@dionysos was right, you have to grow up so you can understand the difference between "American Chemical Society" grade and "US Pharmacopeia" -> do you want to inject chemicals or drugs?
As a person who has conducted (well facilitated more like) clinical trials with Mass Gen and BCH, I can tell you he is winging it. There are many times that NF and USP standard generally equate with ACS.
You can label me a troll or whatever. The truth is the truth. I'm not making this up.
dionysos
GLP-1 Specialist
Not quite the master of your material are you @Deeubee
You felt it necessary to delete your assertion that it was "Just me"
after you looked up the references I made.
I'll just continue to "wing it" here in GLP1forum,
advocating for high drug standards along with the USP, NF and the FDA
while you "facilitate" and suggest that high drug standards don't matter.
There is also a lot of mixing up of terminology. Many times industry wise, these terms are used interchangeably. However, He is right in terms of the standards not just being purity levels. Manufacturing standards also come into play. But are we really saying 99% pure peptide can't fail sterility tests? We don't even test enough for pyrogens (or endotoxins, although for synthetic peps like these, it is less of a problem)
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I decided to be polite and state it better. You will not find any industry wide 99% purity standard as you claim. It's not just by throwing 3 letter regulatory agencies about. We have worked with some of these agencies before and have submitted bales of paperwork. It's not as simple and straightforward as purity = 99%, we gucci... (or Kosher/all set.. before you attack my language again)
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Fight nice.
If you don't like a the peptide purity of a vendor's product, don't buy it.
It's also stupid to get so worked up about purity. I'm sure the cocaine, heroin, and meth for sale on your local street corner isn't exactly pharmaceutical grade either and it costs a lot more. Relax.
If you don't like a the peptide purity of a vendor's product, don't buy it.
It's also stupid to get so worked up about purity. I'm sure the cocaine, heroin, and meth for sale on your local street corner isn't exactly pharmaceutical grade either and it costs a lot more. Relax.
Mounjamen
New Member
I have a big request for the professionals here: Please don't use so many abbreviations or write the explanations in brackets once. We newbies can only guess and look for meaning in the whole text. That would be very nice. Zip has promised to compile a corresponding explanation of the abbreviations, but has probably not got around to it yet. Thank you!
I guess @ZippityDooDah is pretty busy (+ he is active on many forums and groups) and you must understand this server is not for profit (as far as I know), he invest his own time and perhaps also some money to run it. We cant forcing him to do anything, only thing we can do, is to be thankful to him that he created this very special place!
Mounjamen
New Member
My request was not so much directed at the zip but at the many speeches of the participants here. Today, while reading the What's new posts, I put together a whole list and then asked the chatbot if it could explain it to me:
Okay, let me explain these acronyms for you:
HGH - Human Growth Hormone: A hormone that controls growth and development in the human body. It is commonly used as a dietary supplement.
HLFT - High Lift Fitness Tonic: A blend of vitamins, minerals and herbs that is said to increase physical performance.
HBFL-Tech - Hormone Balanced For Life Technology: A technology that is said to regulate and optimize hormonal balance in the body.
OSC-Xce - Organo-Spinal Complex Xanthine Chromium Extract: A composition of herbal extracts that is said to support metabolic functions.
Heibei Orono-Biotech - Believed to be a biotechnology company from Hebei Province in China.
Lipo C - Liposomal Vitamin C: A form of vitamin C that is packaged in fatty shells to allow for better absorption in the body.
Mots-C - Mitochondrial Derived Peptides: Short peptide sequences that are said to be derived from mitochondria and are said to have health benefits.
IMO - Intermittent Fasting Mimicking Oligosaccharides: Special carbohydrates that are said to have similar effects to intermittent fasting.
PTDS - Possibly Toxic Dietary Supplements: A term for dietary supplements that have possible health risks.
Xcel - Probably a brand or product that I don't have any more information about.
Hallandale Version - Also a term that I don't have any information about.
AC-Peptides - Probably a series of peptides that are used in cosmetics or dietary supplements.
LB-Loss - Probably a term for weight loss or fat loss.
Bioboost plus - A mixture of vitamins, minerals and/or other active ingredients that are said to increase physical performance.
I hope these explanations were helpful for you! If you have any further questions, please let me know.
Okay, let me explain these acronyms for you:
HGH - Human Growth Hormone: A hormone that controls growth and development in the human body. It is commonly used as a dietary supplement.
HLFT - High Lift Fitness Tonic: A blend of vitamins, minerals and herbs that is said to increase physical performance.
HBFL-Tech - Hormone Balanced For Life Technology: A technology that is said to regulate and optimize hormonal balance in the body.
OSC-Xce - Organo-Spinal Complex Xanthine Chromium Extract: A composition of herbal extracts that is said to support metabolic functions.
Heibei Orono-Biotech - Believed to be a biotechnology company from Hebei Province in China.
Lipo C - Liposomal Vitamin C: A form of vitamin C that is packaged in fatty shells to allow for better absorption in the body.
Mots-C - Mitochondrial Derived Peptides: Short peptide sequences that are said to be derived from mitochondria and are said to have health benefits.
IMO - Intermittent Fasting Mimicking Oligosaccharides: Special carbohydrates that are said to have similar effects to intermittent fasting.
PTDS - Possibly Toxic Dietary Supplements: A term for dietary supplements that have possible health risks.
Xcel - Probably a brand or product that I don't have any more information about.
Hallandale Version - Also a term that I don't have any information about.
AC-Peptides - Probably a series of peptides that are used in cosmetics or dietary supplements.
LB-Loss - Probably a term for weight loss or fat loss.
Bioboost plus - A mixture of vitamins, minerals and/or other active ingredients that are said to increase physical performance.
I hope these explanations were helpful for you! If you have any further questions, please let me know.
I take no responsibility for your lack of comprehension. I have been pretty consistent. If you aren't clear ask questions. I'm not the one conflating grades here.
The thing is, I wasn't prepared to go into a long diatribe about the various grade requirements for biologics like peptides, but I can tell you that it is not as simple as represented here. Whether something meets USP grade is not merely about 99% Purity. There are other issues like minimum impurity levels, acceptable degradation e.t.c. Lest I digress, my main point has been you will not find an industry wide standard of 99%.. Perhaps I should stop saying "industry wide", and substitute with 'blanket' purity standard of 99%.
The accepted (i use that loosely) minimum is usually 95% Purity. However, to meet USP or NF (well they're merged now and NF will likely soon be done away with), you must refer to a document called a monograph. The monograph is like an FDA ID card for an approved compound. The monograph will tell you the specific purity levels (which may actually vary depending on usage). the tests you will use to identify the compound and specific characteristics of the compound. There is no blanket monographs. Minimum purity of pharma grade compounds will vary from compound to compound and from Use to use. When we tested for antibodies for some ocular pathologies, the minimum purity that would elicit a response was 80%. When a dose dependent response for a peptide therapy was assessed, the minimum was 95% purity.
I'm not here to advise you to buy 96% grade stuff. Just calling out the inaccuracy that FDA regulation is 99 or bust
these are funny explanations! 😉
ok one more last message:
@dionysos wrote that HE PERSONALLY would not use anything below 99%, I said that FOR ME its 98% which is also inline with peppys accepted levels for purity. Most good vendors offer products with >99% purity and that's why we are choosing them over those with 95%...
admin said "If you don't like a the peptide purity of a vendor's product, don't buy it." and "It's also stupid to get so worked up about purity."
- and I agree
so, you take whatever you want and end of discussion.
dionysos
GLP-1 Specialist
@milos @Broken Chef
If we as users do not care about product quality then vendors certainly will not.
Being indifferent to product Purity is not some noble Libertarian ideal we should uphold.
It is intellectually lazy, and it is poor leadership.
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true, true @dionysos im just wondering, consider your timezone, what are you doing online! 🤔
Our discussion about purity maybe contributed to the fact that Tracy/QSC acknowledge the issue and is promising now some solution and even if not, it still shows to vendors that we accept only the best they can deliver - and it is extremely important. If we don't care they will soon start feeding us with rubbish....
but this particular discussion with @Deeubee is really going nowhere, wasting our time only, not adding any value here; and that's why I understand @ZippityDooDah comment about not to get so worked up about purity (but the comparison to street drugs - impurities or cutting agents in street drugs significantly contribute to mortality - so its actually a good example why pure staff matters, Walter White would agree)
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dionysos
GLP-1 Specialist
You make my point precisely milos!
Our behavior and expectations MATTER.
They matter to people around us, and they matter to the vendors..
Quality in all its forms is an ideal that is worthy of our efforts. If it is absent here then I will also be absent.
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It wasn't really a discussion. You ignorantly assumed I was trolling, and Lacoste bruv also dropped his insinuations. It's a pet peeve of mine. As is misrepresentation of standards. That's how confusion starts.
Just be aware that a few pharma biologics you take are being sold with purity percentage specifications of NLT 90%.
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Tired of reading the childish back and forth, so making the rare move to close a thread. Discussion over.
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