GLP-1 Forum

Anhedonia... that blaaaaah feeling.

miss-sanne

GLP-1 Apprentice
Member Since
Sep 8, 2025
Posts
45
Likes Received
55
From
Denmark
So, I was on Tirz for a few months, all went well, good weight loss, minimal side effects, I do love Tirz so much. But at the higher doses 10-11 mg, I started to feel so flat, so bummed, depressed, and 'fuck you all, I'm gonna sit here and read reddit all the time', no will to do anything, no joy. Well I had to go to work, but when I got home, I was just like a 'blaaaaah'.
Apparently, a side effect from Tirz, I didn't have it on Sema.
Waited for at bit, but couldn't stand it.
Titrating down at the moment, going up in Reta, a bit of Cagri.
Feel better, have more energy on the other two.
But this could maybe happen again on Reta.
Does anyone know of any supplements etc, they have used or heard of, to help with this anhedonia ?
Thank you.
 
Hello 👋 I don't know if this suggestion will help in any way. Just my personal experience. Happily on tirz for around 15 months when was slammed (bedridden 😞) with appalling anxiety - for no reason. Am now on a reduced dose of tirz with a small dose of sema mid week. No anxiety. Really it's a matter of trying different peps / blends / dosages. Everyone reacts differently. I'm confident there is a solution to this. Good luck 🤞
 
Hello 👋 I don't know if this suggestion will help in any way. Just my personal experience. Happily on tirz for around 15 months when was slammed (bedridden 😞) with appalling anxiety - for no reason. Am now on a reduced dose of tirz with a small dose of sema mid week. No anxiety. Really it's a matter of trying different peps / blends / dosages. Everyone reacts differently. I'm confident there is a solution to this. Good luck 🤞
That's what I already do, I'm just curious about some solutions out there. That's sounds awful, being bedridden for anxiety !
 
Top Bottom