Anyone else a slow burn with reta?

[peptidepower77]

I didn't have much luck on Mounjaro before - I got up to 7.5mg with only minimal weight loss. I am not a snacker really either, so I don't think I eat a ton. Probably just some metabolic damage from years of being heavy and trying to diet.

Did anyone else have trouble on Mounjaro and eventually have success on reta? I've been getting 10,000 steps a day, going to the gym a few times a week, and trying hard to limit my meals, which isn't that difficult since I finish half my plate and feel like I can't have any more. But I've only last about 3 lbs in my first month, and have started ramping up a bit more aggressively. I had a friend staying with me last month and he was on Mounjaro (his second month) and was down about 15 lbs. We ate pretty much the same meals for a month.

If anyone has been in a similar situation, where low doses didn't do much for them but higher doses did, I'd love to hear it. Thanks.

 

[desinr-gal]

I didn't have much luck on Mounjaro before - I got up to 7.5mg with only minimal weight loss. I am not a snacker really either, so I don't think I eat a ton. Probably just some metabolic damage from years of being heavy and trying to diet.

Did anyone else have trouble on Mounjaro and eventually have success on reta? I've been getting 10,000 steps a day, going to the gym a few times a week, and trying hard to limit my meals, which isn't that difficult since I finish half my plate and feel like I can't have any more. But I've only last about 3 lbs in my first month, and have started ramping up a bit more aggressively. I had a friend staying with me last month and he was on Mounjaro (his second month) and was down about 15 lbs. We ate pretty much the same meals for a month.

If anyone has been in a similar situation, where low doses didn't do much for them but higher doses did, I'd love to hear it. Thanks.

Remember that Muscle is denser and weighs more than fat, so if you're at the gym building muscle; the weight may stay the same for awhile until it raises you BMR higher and you'll drop more quickly. Other people have said it took 4 wks to see the downward progress. Do your clothes fit the same?

 

[peptidepower77]

Do your clothes fit the same?

My clothes fit like I'm fat 🙂

 

[peptidepower77]

Remember that Muscle is denser and weighs more than fat, so if you're at the gym building muscle; the weight may stay the same for awhile until it raises you BMR higher and you'll drop more quickly. Other people have said it took 4 wks to see the downward progress. Do your clothes fit the same?

I just had a DEXA scan done, and I have more than an age-appropriate amount of muscle for my height. So I shouldn't really have a problem with a low RMR, at least not based on a muscle mass. I hope it'll pick up, because it's pretty discouraging, especially when you see a friend drop 15 lbs while still chugging the odd beer and the scale is hardly moving for me.

 

[meeklady]

Reta has been very slow for me! I didn't have any weight loss until I got to around 8 mg ( my current dose.) I have lost 17 lbs now. From what I've read, if you've done other weight loss peptides, then it doesn't work until higher doses. Personally I don't have much weight to lose ( max 20 lbs) so I expect that's not helping! Always harder to lose the last bit! I'd say to trust the process, follow the titration schedule and hope it works when you find your sweet spot.

 

[peptidepower77]

Reta has been very slow for me! I didn't have any weight loss until I got to around 8 mg ( my current dose.) I have lost 17 lbs now. From what I've read, if you've done other weight loss peptides, then it doesn't work until higher doses. Personally I don't have much weight to lose ( max 20 lbs) so I expect that's not helping! Always harder to lose the last bit! I'd say to trust the process, follow the titration schedule and hope it works when you find your sweet spot.

Thanks. I've been going up pretty quick simply because I haven't seen any weight loss yet. I also haven't had any real side effects, certainly none that were worse than tirz. I'm on about 5mg/week now but will start ramping up to 7mg to 8mg I think and see if it picks up.

Did anything change when you got to 8mg? Did the scale just start moving down on its own, or do you think you actively ate a lot less? I don't feel like I'm eating lots, and lots of times for dinner will just have something small. So I honestly don't think I could eat much less without being in danger of eating too little. So I'm hoping the glucagon part kicks in and starts helping even with the current amount of food. What was your experience ramping up and when it finally started working for you?

 

[FrankTdog]

Some people are just slower at losing the weight, don't worry about your friend's progress. 3lb a month is right in the healthy weight loss range (generally given as 0.5 to 2 lb per week).

 

[lemon lady]

It's a slow burn for me also, I only lost 1kg in the first month, now I either lose 0.5kg pw or nada (I started at 1mg and now at nearly 10 weeks I'm at 6mg) , I rage read posts where people can't eat the first week and lost 5kg 😪

 

[nurseratchit]

I didn't have much luck on Mounjaro before - I got up to 7.5mg with only minimal weight loss. I am not a snacker really either, so I don't think I eat a ton. Probably just some metabolic damage from years of being heavy and trying to diet.

Did anyone else have trouble on Mounjaro and eventually have success on reta? I've been getting 10,000 steps a day, going to the gym a few times a week, and trying hard to limit my meals, which isn't that difficult since I finish half my plate and feel like I can't have any more. But I've only last about 3 lbs in my first month, and have started ramping up a bit more aggressively. I had a friend staying with me last month and he was on Mounjaro (his second month) and was down about 15 lbs. We ate pretty much the same meals for a month.

If anyone has been in a similar situation, where low doses didn't do much for them but higher doses did, I'd love to hear it. Thanks.

3 pounds in a month sounds heavenly. It’s taken me a year to lose almost 15 pounds. But you can’t compare yourself to others. I was on tirz first and then switched to reta. Increasing to higher doses doses did not result in a faster rate of weight loss. It’s always been difficult for me to lose weight but the difference now is it not such a battle to just stay the course and keep up with the healthier diet and exercise habits.

I have found it helpful to focus on the other health benefits I’ve received which is lower blood pressure, lower A1C, cholesterol values all normal for the first time in 15 years and just an easier relationship with food.

 

[meeklady]

Thanks. I've been going up pretty quick simply because I haven't seen any weight loss yet. I also haven't had any real side effects, certainly none that were worse than tirz. I'm on about 5mg/week now but will start ramping up to 7mg to 8mg I think and see if it picks up.

Did anything change when you got to 8mg? Did the scale just start moving down on its own, or do you think you actively ate a lot less? I don't feel like I'm eating lots, and lots of times for dinner will just have something small. So I honestly don't think I could eat much less without being in danger of eating too little. So I'm hoping the glucagon part kicks in and starts helping even with the current amount of food. What was your experience ramping up and when it finally started working for

Thanks. I've been going up pretty quick simply because I haven't seen any weight loss yet. I also haven't had any real side effects, certainly none that were worse than tirz. I'm on about 5mg/week now but will start ramping up to 7mg to 8mg I think and see if it picks up.

Did anything change when you got to 8mg? Did the scale just start moving down on its own, or do you think you actively ate a lot less? I don't feel like I'm eating lots, and lots of times for dinner will just have something small. So I honestly don't think I could eat much less without being in danger of eating too little. So I'm hoping the glucagon part kicks in and starts helping even with the current amount of food. What was your experience ramping up and when it finally started working for you?

when I got to 4 or 6 I started having crazy appetite suppression- I've literally had to force myself to eat a couple of mouthfuls. Food is not appealing and I feel zero appetite. I doubt I manage a 1000 calories most days, still the scale wasn't moving! I also have a less sedentary job- hit 10,000 plus steps a day at work.

Now I'm up to 8 mg the scale is moving! Went from 155 to 135 ( 5 ft 1.) I've had minimal side-effects too. My RHR is 59 today and maybe goes up to 61-63 just after the shot. I have allodynia when I increase doses but it has died down now. At times I get dizzy and have to eat something or drink an ensure but that's lack of calories for you! Very rarely I feel nauseous but don't vomit.

In theory I should have lost weight much earlier so it's not as simple as cico. There's something about Reta, where you have to get to a certain dose for the weight loss to happen- at least for me and maybe for you. I'm on my 5th week at 8 mg and planning on staying there- hoping to get to 120 lbs without having to go up anymore! The low calories can't be good for us so I'd like to lose all the weight and get to some kind of maintenance dose so I can eat a little more! Hope my story gives you some hope that the magic can happen- EVENTUALLY!!!

 

[peptidepower77]

when I got to 4 or 6 I started having crazy appetite suppression- I've literally had to force myself to eat a couple of mouthfuls. Food is not appealing and I feel zero appetite. I doubt I manage a 1000 calories most days, still the scale wasn't moving! I also have a less sedentary job- hit 10,000 plus steps a day at work.

Now I'm up to 8 mg the scale is moving! Went from 155 to 135 ( 5 ft 1.) I've had minimal side-effects too. My RHR is 59 today and maybe goes up to 61-63 just after the shot. I have allodynia when I increase doses but it has died down now. At times I get dizzy and have to eat something or drink an ensure but that's lack of calories for you! Very rarely I feel nauseous but don't vomit.

In theory I should have lost weight much earlier so it's not as simple as cico. There's something about Reta, where you have to get to a certain dose for the weight loss to happen- at least for me and maybe for you. I'm on my 5th week at 8 mg and planning on staying there- hoping to get to 120 lbs without having to go up anymore! The low calories can't be good for us so I'd like to lose all the weight and get to some kind of maintenance dose so I can eat a little more! Hope my story gives you some hope that the magic can happen- EVENTUALLY!!!

Yah, it's hard to say what causes the shift. I suspect in reta it's a combination of a) clearing out the liver fat first and b) the slow effects of the glucagon receptor part of it, which mobilizes more fat to be burned. At some point those probably kick in and make reta work much faster.

But yes, thanks for the inspiration. I ramped up pretty quick and don't really have any side effects other than appetite suppression. But others said if you've been on a GLP1 before it won't work until higher doses. I'm at 4mg twice a week now, and the scale seems to be slowly going down now. So hopefully this is my threshold dose. I'd like to stay here for a while too without ramping up, but I just ordered 3 kits of 50mg retatrutide so I can survive an apocalypse haha. So I should be good either way!

 

[meeklady]

Yah, it's hard to say what causes the shift. I suspect in reta it's a combination of a) clearing out the liver fat first and b) the slow effects of the glucagon receptor part of it, which mobilizes more fat to be burned. At some point those probably kick in and make reta work much faster.

But yes, thanks for the inspiration. I ramped up pretty quick and don't really have any side effects other than appetite suppression. But others said if you've been on a GLP1 before it won't work until higher doses. I'm at 4mg twice a week now, and the scale seems to be slowly going down now. So hopefully this is my threshold dose. I'd like to stay here for a while too without ramping up, but I just ordered 3 kits of 50mg retatrutide so I can survive an apocalypse haha. So I should be good either way!

I haven't had any blood tests since starting Reta so will be interested to see how they are looking. After a year of Sema, my bloods looked good and the last few months before having them, I was eating pretty normally. My only worry is that my Creatinine was at 51 after being on Sema, eating better than what I am now. I'm hoping that isn't a lot lower now because I'm seriously lacking on the protein side of things. Need to make an appointment and will update the results!

 

[peptidepower77]

Do you take any creatine supplements? I had a high value once that freaked me out, then I remembered I had been adding creatine monohydrate to my smoothies, which artificially raises it.

 

[Armadillo]

It is really dependent on the person. I am like your friend but to an extreme with reta. Within 2 months of my 2mg/week, I was able to drop 3% bodyfat (18 to 15%) and only 5lbs lost (I started at a very healthy BMI btw, which is important context here). This was my dream scenario as I didn't want to lose too much weight, granted I am on test and workout for 2-3 hours 6 times/week. I just happen to be incredibly sensitive to reta, and I actually had to drop my dose down to 1mg/week as I was eating in a dangerous deficit.

Potential feedback here:

• track every single thing you eat/make... this includes the minute details like the exact measured amount of oil in your pan and water intake. 9 times out of 10 I've found when people guess their macro nutrients they drastically underestimate what they are really consuming. I'm just making the assumption you're not tracking everything based on some of the language used.
• over time, figure out what your maintenance calorie intake is... all the calculators out there based on bmi are pretty inaccurate, everyone has their own ideal caloric intake that is considered maintenance
• in your workouts, make sure you are doing sufficient volume for each muscle group while actually failing to complete your last rep. This last piece is what I see nearly everyone staying the same in the gym failing to do. I like to hit a spot where I could not lift my final rep past half a motion no matter how hard I shake and scream. The important part here is to keep good form. If you are failing your final rep with bad form, you need to drop weight and focus on form because you're going to end up injuring yourself.
• unless you are obese, do not make your main priority cardio, people often focus too much on this when new to it. Pick a day or two out of the week when you're at the gym to add light cardio into your routine, whatever feels best for you to sustain and keeps your heart rate up. Personally, I've found casually (3-3.5mph) walking a mile before I stretch for my lifts every day is more than enough for me, with 1 day of the week getting a good run in.

 

[mopo89]

I think titrating up quickly is the wrong way to go about it. The titration schedule was developed for a reason and the drug needs time to build up in your system. 3lbs/month is in the range of healthy weight loss. The only reason you're titrating up quicker is because of one thing - impatience. And impatience can be dangerous and unhealthy.

I mean, at the end of the day, you do you, but being at 8mg after a month is insane.

 

[peptidepower77]

I think titrating up quickly is the wrong way to go about it. The titration schedule was developed for a reason and the drug needs time to build up in your system. 3lbs/month is in the range of healthy weight loss. The only reason you're titrating up quicker is because of one thing - impatience. And impatience can be dangerous and unhealthy.

I mean, at the end of the day, you do you, but being at 8mg after a month is insane.

We only have one study really that investigated the titration schedule, and they started one group at 1mg, one at 2mg, and even one at 4mg. Until it's actually released we don't have an official titration schedule. What we know is that the 4mg group lost weight faster, and on day 29 (after four weeks) they bumped up to 6mg/week.

 

[mopo89]

like i said, you do you dude. no one can stop you from being reckless! if 8mg/week is what your heart desires, then no one can stop you. but i think we encourage people to be a little more conservative here and give the drug time to do what it's supposed to it. 🤷‍♀️

 

[peptidepower77]

like i said, you do you dude. no one can stop you from being reckless! if 8mg/week is what your heart desires, then no one can stop you. but i think we encourage people to be a little more conservative here and give the drug time to do what it's supposed to it. 🤷‍♀️

All good, I'm only going to do 6mg/week for my second month, which a large amount of people in the study also did. You clearly have an opinion about that, but this was part of the study protocol as well. Appreciate the feedback though.

 

[Calm Logic]

3lbs/month is in the range of healthy weight loss.

More like 1 to 2 percent of total body weight, or 1 to 2 pounds per week for normies.