Is the weight loss effect of retatrutide really that powerful?

Im on Tirzepatide and take 1.5ml Lipo-B once/ week
I bought a bunch of Reta in a group buy last year, but have been too chicken to try it lol. Sema and tirz are being used by hundreds of thousands of people (and are "FDA approved" not that I think that's an absolute requirement for me), but reta is still only being used by a tiny fraction and the handful of heart complications reported in the trial is enough to scare me off for now. I think I'm going to have to wait another while before giving it a try for my own peace of mind.

I've been fortunate that tirz fatigue hasn't really be an issue for me, but I'm currently trying to cut way back on my absurd caffeine intake so I've definitely been feeling more run down the past few weeks.

I'm getting ready to sign up for Defy and try their Lipo-C which a lot of people have reported has helped tremendously.

. Never feel fatigue.It helps.
 
Reta just made me hungrier than Tirz even at higher doses. So I wasn’t losing or gaining because of the increased heart rate (which I could feel) and energy expenditure of Reta. In the end I think Tirz + something like Cagri low dose is a better bet
 
I got full quicker on Tirz, but the Tirz exhaustion was a real issue for me. I get none of that on Reta, which has lead to me being more consistent with exercise.
I can relate to the Tirz exhaustion. What were your most recent dosing regimens for both Tirz and Reta?
 
I can relate to the Tirz exhaustion. What were your most recent dosing regimens for both Tirz and Reta?
I was at 10mg on Tirz, and now I'm at 9mg Reta. I was gettting the exhaustion even with 5mg of Tirz. I stuck with it hoping it would go away, but it never did. I tried splitting, but that just made it worse honestly.

I juuust moved up to 9mg of Reta, and the satiation effect is definitely more noticeable now.

I do remember reading that sometimes it takes longer to see results with Reta than with Tirz, maybe there's something to that. I've lost a little weight still, but most of the weight I've lost was while on Tirz.
 
Your example makes me wonder if Reta might be better for people using GLP-1s for appetite regulation, insulin control, food addictions, etc. more so than weight loss. Or those that have lost most of their excess weight on Sema/ Tirz and want to slow it down while mitigating lethargy.

Other than that, I think the Tirz/Cagri is a good option if Reta doesn’t work out. There are probably lots of us who get incredible benefits from Sema/ Tirz, but are reluctant to add harsher stimulant supplements to deal with fatigue.

Over the past few months, I tried Semax, Bromantane, and fladrafinil individually and combined with no noticeable boost. Methylene blue is slightly effective so far!
 
Your example makes me wonder if Reta might be better for people using GLP-1s for appetite regulation, insulin control, food addictions, etc. more so than weight loss. Or those that have lost most of their excess weight on Sema/ Tirz and want to slow it down while mitigating lethargy.

Other than that, I think the Tirz/Cagri is a good option if Reta doesn’t work out. There are probably lots of us who get incredible benefits from Sema/ Tirz, but are reluctant to add harsher stimulant supplements to deal with fatigue.

Over the past few months, I tried Semax, Bromantane, and fladrafinil individually and combined with no noticeable boost. Methylene blue is slightly effective so far!
Im ADD and have an addy script, and even that didn't help.
 

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