My Cagri Chronicle: ongoing updates on progress with cag starting October 2024

Today is tirz 10mg day. I would say that the cagri 0.25mg did a fabulous job getting me through days 4-7 of the tirz cycle. i had good appetite suppression all weekend, although by monday i didn't feel much anymore. I also had increased fullness, I could only eat small portions.

very little side effect with cagri, i think maybe i had some fatigue on saturday and sunday afternoon, but that also may have just been saturday and sunday afternoon normal sleepiness. nothing unbearable. I also made sure to do electrolytes, b12, and vit d.

i hit a new low weight on friday, busting a 3-4 week stall. hoping for another low this week.

plan for this week is 10mg tirz on monday and stay with the 0.25 cag on thursday. hopefully by thursday i can sort out whether i should be worried about my sry cag being laced with fentanyl.
it wasn't, I take it? 🙂
 
Do you guys find cagri reduces your blood sugars by much? Also which has better appetite suppression cagrisema or just cagri? Keeping sides in mind so far cagri sides have been ok
 
Do you guys find cagri reduces your blood sugars by much? Also which has better appetite suppression cagrisema or just cagri? Keeping sides in mind so far cagri sides have been ok
From the GLP1's I've tried only Cagri reduced my glucose. I'm normally FG 99-104 and since started cagri has hovered from 85-93, Reta and tirze had no effect at all for some reason, maybe because I wasn't diabetic to start with? Never tried cagrisema. and Cagri seems to have a bit of more pronounced appetite suppression for me though both tirze and reta had great effect initially (when started taking them) then effect would fade after a while.
 
Do you guys find cagri reduces your blood sugars by much? Also which has better appetite suppression cagrisema or just cagri? Keeping sides in mind so far cagri sides have been ok
I can't tell a difference, I tried cagrisema because I got a little cheap. In 2 weeks I'll be back to cagri and can report back
 
From the GLP1's I've tried only Cagri reduced my glucose. I'm normally FG 99-104 and since started cagri has hovered from 85-93, Reta and tirze had no effect at all for some reason, maybe because I wasn't diabetic to start with? Never tried cagrisema. and Cagri seems to have a bit of more pronounced appetite suppression for me though both tirze and reta had great effect initially (when started taking them) then effect would fade after a while.
Just got to from a 10 hour sleep and keep waiting for you to say it hit you
 
Yeh im finding cagri keeps my glucose under 5.2 but lets see how long it works before I need to bump it up
Tnx for the replies, much appreciated

Edit* for you guys in the US that is a fasting sugar of around 94.
 
LOL no nothing yet. Just appetite suppression, but I can eat when/if I want. Almost two days have passed so i guess i weathered the storm. 😊
I'm glad to hear that! Don't die, guys.
Today I went with 0.125mg cagri to stack with my 7.2mg tirz. Hoping to break out of the super-slow-mode loss cycle I'm in. I've bumped my tirz for the past three weeks to not much success.
 
I'm glad to hear that! Don't die, guys.
Today I went with 0.125mg cagri to stack with my 7.2mg tirz. Hoping to break out of the super-slow-mode loss cycle I'm in. I've bumped my tirz for the past three weeks to not much success.
Yeah, some of us we're made of steel it seems lol, 4mg cagri two days ago and nothing no sides whatsoever other than appetite suppression. I hear people having sides on dose 40 times smaller, goes on to show how we all act differently to these meds. For me though even on a very high dose of cagri, I think I like it better than GLP1's. Today I felt great but could have been either cagri, or the fact I ate very little food yesterday (on purpose) and usually when I fast I feel real good.
 
Question to those who have tried both cagri (alone) and cagrisema combo: do you find a greater reduction in blood glucose and hunger with cagri alone or with cagrisema?

I have read many scientific studies on this topic (greater reduction with cagrisema) but I want to hear individual first hand accounts from the members here.

Scientific journals are not the be all and end all of everything. Prime example Nova Nordisk is currently trialing sema weekly dose of 7.2mgs …

That to me that seems reckless and irresponsible even. I personally was not able to handle more than 1.65mg weekly dose of sema without severe sides.

I ended up getting pancreatitis and found my sweet spot with sema no dose higher than 0.8mgs so thats where I will stay.

I know some other forum members are even trialing cagrireta and saying stuff like this is the GOAT stack. I havent tried this stack yet …
 
Question to those who have tried both cagri (alone) and cagrisema combo: do you find a greater reduction in blood glucose and hunger with cagri alone or with cagrisema?

I have read many scientific studies on this topic (greater reduction with cagrisema) but I want to hear individual first hand accounts from the members here.

Scientific journals are not the be all and end all of everything. Prime example Nova Nordisk is currently trialing sema weekly dose of 7.2mgs …

That to me that seems reckless and irresponsible even. I personally was not able to handle more than 1.65mg weekly dose of sema without severe sides.

I ended up getting pancreatitis and found my sweet spot with sema no dose higher than 0.8mgs so thats where I will stay.

I know some other forum members are even trialing cagrireta and saying stuff like this is the GOAT stack. I havent tried this stack yet …
I don't monitor glucose sorry
 
ok, did my own version of the FULL SEND today. i had a terrible week of hunger and snacking last week so i decided now is finally time to go from tirz 12.5 to 15. but egads, i could only draw 11.7mg remaining out of the vial! the rest of my vials are 30mg each so i didn't want to get caught in a cycle of half doses in every vial so i decided to pin just the 11.7mg.

and i also had 1mg/1mg of cagrisema left in a vial so i pinned that too. 11.7mg tirz, 1mg cag, 1mg sema on monday morning. and i'll fire up a new vial of cag on thurs/fri this week if i need to.

gained a couple pounds last week, snacked a lot, ready to nip this in the bud and get those last 10-15 pounds out of here, lfg.
 
ok, did my own version of the FULL SEND today. i had a terrible week of hunger and snacking last week so i decided now is finally time to go from tirz 12.5 to 15. but egads, i could only draw 11.7mg remaining out of the vial! the rest of my vials are 30mg each so i didn't want to get caught in a cycle of half doses in every vial so i decided to pin just the 11.7mg.

and i also had 1mg/1mg of cagrisema left in a vial so i pinned that too. 11.7mg tirz, 1mg cag, 1mg sema on monday morning. and i'll fire up a new vial of cag on thurs/fri this week if i need to.

gained a couple pounds last week, snacked a lot, ready to nip this in the bud and get those last 10-15 pounds out of here, lfg.
sounds fun! add a little reta for a cherry on top! my stack so far 15mg of tirz 1mg of cagri every 3 days and 2mg of reta in the middle
 
as my stomach is much much acidic.
Interesting you mention that. I used to have that issue with Reta and Tirze, but Cagri seems the opposite, seem more alkaline to me, and my stomach feels great when I added cagri. Could be just me, or is anyone else feeling the same? Unless it is TB 500 having that effect, as I've been pinning it about same as I started Cagri, so its either cagri or TB, but very comforting since the acid reflux was bothering me quite a bit.
 
How much are you loosing each week? Am increasing all 3 also, slowly, as my stomach is much much acidic.
lets say i've lost more weight on this combo then any other i've tried so far. prolly down 3-4 a week but i diet and workout daily as well. I think Tirz and cagri are amazing after you get over the frist few weeks of tired feeling. I also pin TRT twice a week and Lipo-c a few times a week
 
Interesting you mention that. I used to have that issue with Reta and Tirze, but Cagri seems the opposite, seem more alkaline to me, and my stomach feels great when I added cagri. Could be just me, or is anyone else feeling the same? Unless it is TB 500 having that effect, as I've been pinning it about same as I started Cagri, so its either cagri or TB, but very comforting since the acid reflux was bothering me quite a bit.
Reflux has subsided over time but I never connected it with cagri. Maybe 🤔???

I feel great so far today. Had a protein shake, some leftover sloppy joe meat, and some pretzels. Will be ready for dinner at dinner time. Also purging retained water from my carbo load last weekend
 
Guys wish me luck, I just pinned myself with 3mg of Cagri thinking I was pinning Tirze. Plus I had already pinned yesterday about 0.7mg. Holly molly it will be fun in next couple days lol
I'll keep you posted(if I'll live to tell hahaa). Does anyone know what's the highest anybody has done?
It's been almost six days since I did 4mg of cagri (by mistake) and not only the rapid losing has returned but I seem to be melting away lol. lost 7lbs in five days. No side effects other than appetite suppression, so yes cagri seems a sure bet if your losing has stalled. btw I'm also pinning 5mg of tirze every Monday.
 
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It's been almost six days since I did 4mg of cagri (by mistake) and not only the rapid losing has returned but I seem to be melting away lol. lost 7lbs in five days. No side effects other than appetite suppression, so yes cagri seems a sure bet if your losing has stalled. btw I'm also pinning 5mg of tirze every Monday.
Wow congrats. That's a huge week. I need a couple of those.

So what now? You going to do it again next week?
 
Wow congrats. That's a huge week. I need a couple of those.

So what now? You going to do it again next week?
no not that much. I pinned 1mg cagri last night as my apetite started to creep up again, and my usual 5mg tirze on Monday. I don't know if you are doing cagri or how you are reacting to it, but i would up the dose of cagri if I were you (in case you haven't been able to start losing again). I would not do more than 1.5 to 2mg though as I'm sure that would be enough for most if not all people. And if you get some of the symptoms just go easy on food, very light. One day I only ate two apples for example, as I felt my stomach might not want much else. Basically i would stick with your favorite fruits as they're are easy to digest.
 
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no not that much. I pinned 1mg cagri last night as my apetite started to creep up again, and my usual 5mg tirze on Monday. I don't know if you are doing cagri or how you are reacting to it, but i would up the dose of cagri if I were you (in case you haven't been able to start losing again). I would not do more than 1.5 to 2mg though as I'm sure that would be enough for most if not all people. And if you get some of the symptoms just go easy on food, very light. One day I only ate two apples for example, as I felt my stomach might not want much else. Basically i would stick with your favorite fruits as they're are easy to digest.
yeah i'm tirz + cag 5 days later. it's all documented in this thread. been doing 12.5 tirz + 1mg cagrisema to now, getting ready to go to 15mg tirz monday, switching back to straight cag, will up dose probably to 1.5mg to start.

also just upped from adderall 10mg 2x/day to 15mg 2x/day and that seems to be holding off the appetite today as well
 
Update for this week. The tirz 11.7mg + cagrisema 1mg/1mg on Monday seems to be doing well. I hit my January goal weight a week or two ago but I was in a state of dehydration so it was kind of cheating. Today on Jan 30 I was still 2 pounds higher when I got up, so I rushed downstairs and pinned another 1mg of cagri with plans to basically fast today.

An hour later went I went to shower I tried again and the scale had moved to a new low (by 0.2 pounds) and a little below my January goal - but this time not dehydrated!

So we'll see how this extra cag treats me this weekend.

4 pounds to go to my February goal and I can probably cheat my way there (hot epsom salt bath, bottle of wine, cardio exercise the night before a weigh in lol).

Also got labs back this week and they are stunningly good. Cholesterol, blood counts, liver and kidney function, all look excellent. Testosterone on the low end but normal, and criminally deficient in Vit D so I'm maxing out on 4000 IU/day for a while. But my labs make me look like a healthy human being. Blood pressure also in the 120s/80s range and the AHI on my CPAP device is running in the 3s and 4s most nights, hasn't been that low since I started therapy.

Everything's coming up roses
 
Also wanted to note recently increased energy levels, alertness and wakefulness. There is a new stack in town, and I'm a terrible scientist, lacking a control sample, but in the last two weeks I have:
- not been drinking
- consistently taken a sublingual b12 daily
- started liposomal nad+ for funsies
- maxed out on vit D at 4000 IU/day for a few days
- kept up with the aforementioned tirz/cagrisema stack

something in this stack has given me a boost, in the mornings especially i feel alert and awake, i can almost physically feel my eyes being open wider. I really want to credit the NAD+ but i'm afraid it might just be that i've cut out alcohol for a couple weeks.

anyway, i've been feeling amazing man. not used to this.
 
anyway, i've been feeling amazing man. not used to this
Same here, I think I'm being addicted (in a good way) to this peptide thing. Feel better than ever felt in last 10-15 years.
5mg tirze
1.7mg cagri

TB-500
bpc
semank
semax
mot-c
epitalon
cialis
 
Same here, I think I'm being addicted (in a good way) to this peptide thing. Feel better than ever felt in last 10-15 years.
5mg tirze
1.7mg cagri

TB-500
bpc
semank
semax
mot-c
epitalon
cialis
i'm terrified now that i'm going to end up having to lift some weights or something to get to the next level. i play a lot of tennis and i'm in good fitness condition but i am NOT strong and don't really enjoy lifting. but i fear it's in my future, at least to some extent
 
i'm terrified now that i'm going to end up having to lift some weights or something to get to the next level. i play a lot of tennis and i'm in good fitness condition but i am NOT strong and don't really enjoy lifting. but i fear it's in my future, at least to some extent
At least you do play tennis. I'm not a fan of exercise period. LOL. But yeah, I do see light/moderate weightlifting and light cardio in near future also. We've got to protect the gains (in this case the loses in weight) we've made. I guess Glp1's spoiled us 😊
 
At least you do play tennis. I'm not a fan of exercise period. LOL. But yeah, I do see light/moderate weightlifting and light cardio in near future also. We've got to protect the gains (in this case the loses in weight) we've made. I guess Glp1's spoiled us 😊
i have no answers on how to get mostly sedentary people like myself to consistently get some exercise, nothing in history has worked for me in a sustained way. the tennis thing seems good, i'm going on a couple years now, i play a couple times a week, it's good exercise but the nature of the game means it's not exhausting - you aren't running nonstop for hours, and being on a couple of teams means you get scheduled to play and don't have to force yourself to the gym. i'm not an elite athlete at this pace but i get my heart rate going and my calf muscles look great.

BUT - my overall point is, i don't really have any other good ideas on how to keep yourself active if it's not your style. it's hard. joining some sort of group or team might help with accountability, and i think another thing is that there is more and more research emerging that just shows WALKING to be an incredibly healthy activity. If nothing else, can you go for a 30 minute walk at lunchtime a few days a week? take a walking meeting? walk the dog? the recent studies on walking are just mind-blowing, it makes a huge difference.
 
i'm terrified now that i'm going to end up having to lift some weights or something to get to the next level. i play a lot of tennis and i'm in good fitness condition but i am NOT strong and don't really enjoy lifting. but i fear it's in my future, at least to some extent
You won’t enjoy lifting until a few weeks after you start. I used to love cardio and relied on it for mood/ weight loss. But my body looks and feels better doing more weights than cardio. I know it’s so hard mentally to begin.
 
It's been almost six days since I did 4mg of cagri (by mistake) and not only the rapid losing has returned but I seem to be melting away lol. lost 7lbs in five days. No side effects other than appetite suppression, so yes cagri seems a sure bet if your losing has stalled. btw I'm also pinning 5mg of tirze every Monday.
my full send of 11.7mg T, 1mg Cag, 1mg sema on Monday, 1mg cag on thursday is really doing the trick this week. down 4 pounds, barely ate yesterday and not hungry today. 3 pounds to go to hit my february goal and the entire month to do it.

i made another forum post about whether i'll ever have the magic back of those first few weeks on tirz, and lo and behold, throwing the kitchen sink of glp's at myself gave me the magic again - at least for 36 hours!

i'm out of sema now so next week is tirz 15mg + cagri tbd and i'm considering doing 1mg with the tirz on monday and 1mg on thurs/fri but not sure yet
 
my full send of 11.7mg T, 1mg Cag, 1mg sema on Monday, 1mg cag on thursday is really doing the trick this week. down 4 pounds, barely ate yesterday and not hungry today. 3 pounds to go to hit my february goal and the entire month to do it.

i made another forum post about whether i'll ever have the magic back of those first few weeks on tirz, and lo and behold, throwing the kitchen sink of glp's at myself gave me the magic again - at least for 36 hours!

i'm out of sema now so next week is tirz 15mg + cagri tbd and i'm considering doing 1mg with the tirz on monday and 1mg on thurs/fri but not sure yet
Wait a minute... are you doing Tirz, Cagri & Sema the same day???
 
Wait a minute... are you doing Tirz, Cagri & Sema the same day???
had a cheap vial of cagrisema i was working through. only pinned on the same day one time because my tirz vial was slightly short of the full dose. it's gone now. down to tirz+cag now, on different days
 
I’ve had great success stacking cagri with tirz. I did tirz alone for 3 months and cagri/tirz for 3 months so far - greater average weight loss/wk with cagri/tirz. I was pinning tirz every 5 days when I started the stack but transitioned to every 6 days and now 7 days. Currently on 8.25mg T and 500mcg C.
 
I'm on week 2 of my Cagri/Tirz stack and the first week I went with 0.125mg and didn't notice much. I took my second Cagri dose two days ago and bumped it to 0.2mg - about 20 hours later I noticed I had zero appetite and was a bit sleepy. I'm assuming this is the Cagri? Is a 20 hour results window about accurate for others? Thanks very much! And I know it has a longer half-life so I'm assuming the bioavailable mg will accumulate over time if I take it weekly... I wish the Shotsy app had a Cagri option to map over the top of my Tirz chart!
 
I'm on week 2 of my Cagri/Tirz stack and the first week I went with 0.125mg and didn't notice much. I took my second Cagri dose two days ago and bumped it to 0.2mg - about 20 hours later I noticed I had zero appetite and was a bit sleepy. I'm assuming this is the Cagri? Is a 20 hour results window about accurate for others? Thanks very much! And I know it has a longer half-life so I'm assuming the bioavailable mg will accumulate over time if I take it weekly... I wish the Shotsy app had a Cagri option to map over the top of my Tirz chart!
Curious as well as I am looking to start this week...
 
I'm on week 2 of my Cagri/Tirz stack and the first week I went with 0.125mg and didn't notice much. I took my second Cagri dose two days ago and bumped it to 0.2mg - about 20 hours later I noticed I had zero appetite and was a bit sleepy. I'm assuming this is the Cagri? Is a 20 hour results window about accurate for others? Thanks very much! And I know it has a longer half-life so I'm assuming the bioavailable mg will accumulate over time if I take it weekly... I wish the Shotsy app had a Cagri option to map over the top of my Tirz chart!
That does track with my early experience. I felt some suppression basically right away, same morning, but it really hit me the next day. and yeah, the sleepiness which comes in waves for 30-45 minutes and makes you feel like you can't keep your eyes open. often happens after i eat, even a small meal.

fwiw the fatigue seems to get better after 5-6 weeks
 
Would you suggest taking it before bed?
hard for me to say, i guess i don't tend to get side effects hitting in the first 8-10 hours so i'm not sure taking it before bed would help, at least for me. I usually pin about 9am and I get good appetite suppression on the day I pin, the next day, and some the third day. Side effects I'd say hit most heavy on day 2 and some on day 3
 
Where is the guy that took like 4MG of this stuff I want to hear more about his week lol
The guy is right here lol...I went back to 1 to 2mg (basically last I did 1/3rd of 5mg, but I think the batch i got was testing like 6mg, so its more like 2mg) Still feel great, no side effects and decent appetite suppression (not as big as the 4mg though). As I had mentioned earlier, I don't seem to have any side effects from GLP1's or any other peptides I'm doing, but for whatever reason I feel real good couple days after I pin the cagri. Kind of hard to explain but it is an overall sense of wellbeing which i don't seem to get from tirze or reta as an example (even though they both have appetite suppression at the right dose). I don't know what to make of it, other than to make sure i fill 50% of my freezer with cagri. Waiting for my next fill from my budy at nexaph when available LOL.
 
Is it possible to to be allergic to cagri?

Took 1ml of the vial I'd already made (6.46 mg to 3.1ml bac) and added 2ml bac in a pen to make it easier to dose. Did 6u, which is .0415mg. There's NO WAY I should feel this sick with that dose. 🤢 But maybe I'll break my stall of a month?
 
Did 6u, which is .0415mg. There's NO WAY I should feel this sick with that dose
nah I don't think that is normal, you shouldn't be feeling anything on that little. You are probably allergic or something. If you feel sick on such low dose, you might as well call it a day and don't do cagri again. Just try something new/else (i.e.suvo, or mazi etc..)
 
nah I don't think that is normal, you shouldn't be feeling anything on that little. You are probably allergic or something. If you feel sick on such low dose, you might as well call it a day and don't do cagri again. Just try something new/else (i.e.suvo, or mazi etc..)
I'll see if I get as sick as last time, but if it doesn't work out @clayd will get some nice mail. Maybe I'll eat like a human for a few days (I've definitely been undereating for at least a month, I'll have to eat spoonfuls of Nutella or something) and if that doesn't work I'll probably try stacking with tirz. My survo and reta are recent GB purchases, so I only have the three options right now.
 
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I'll see if I get as sick as last time, but if it doesn't work out @clayd will get some nice mail. Maybe I'll eat like a human for a few days (I've definitely been undereating for at least a month, I'll have to eat spoonfuls of Nutella or something) and if that doesn't work I'll probably try stacking with tirz. My survo and reta are recent GB purchases, so I only have the three options right now.
are you taking vitamins or lipo-c? also liquid IV helps me out alot
 
I'll see if I get as sick as last time, but if it doesn't work out @clayd will get some nice mail. Maybe I'll eat like a human for a few days (I've definitely been undereating for at least a month, I'll have to eat spoonfuls of Nutella or something) and if that doesn't work I'll probably try stacking with tirz. My survo and reta are recent GB purchases, so I only have the three options right now.
if you are certain about the amount you took, yeah, that is an exceedingly small dose to get very sick on. fwiw i also bought some leftover cagrisema from someone else on here who said it made them throw up a lot, so maybe there's something in there that doesn't agree with some people.

sorry to hear it's bothering you so much. i agree with supertrips that generally electrolytes and vitamin b12 seem to help me ward off side effects but this sounds like something worse than standard side effects

i did note that novo's recent release with trial results showed only like 59% of cagrisema patients stayed on it through the whole trial, but they've been a little shifty about why...
 
Is it possible to to be allergic to cagri?

Took 1ml of the vial I'd already made (6.46 mg to 3.1ml bac) and added 2ml bac in a pen to make it easier to dose. Did 6u, which is .0415mg. There's NO WAY I should feel this sick with that dose. 🤢 But maybe I'll break my stall of a month?
You haven't had great luck lately. I am so sorry you are sick again. 😢
 

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