My Cagri Chronicle: ongoing updates on progress with cag starting October 2024

Week 4 Update on tirz10 + cagri 0.25mg

this update is long and rambling, i'll go back and put some of the salient points in bold to save you time, dear reader:


I am pretty sure I wrote an update last week but maybe I forgot to post it. Weird.
This week the tirz 10 seemed even more effective than usual, my appetite was gone Monday - Wednesday. had my usual cycle of tirz side effects that is almost predictable now. insomnia on night one. opposite gastro effects on day 2 and 3. maybe a little aloofness here and there. but nothing too bad.

I thought about skipping the cagri this week since tirz still seemed to be strong. But I went ahead with 0.25mg yesterday. strong appetite suppression so far. Forgot to eat lunch and could only eat a protein cookie for dinner, until after I played a couple hours of tennis, then I was able to fit in a chicken leg and half a deli sandwich.

Still feeling strong suppression today, it's 10am and I just realized I never did my morning protein shake so I am doing that now.

The fatigue on week 3 was much better, and also better starting out on week 4 so far. I was tired at bedtime but not during the day or evening. Hopefully that's going to stay better.

independent testing on my sry cagri 5 came back good. I just contributed to the cost as part of a small group so I don't want to post the coa without their permission, and i'm just slipping this detail into my broader update. but the sry c5 tested good.

i didn't lose any weight on the scale this week...or maybe a half pound depending on which reading you believe. but I didn't gain any either. I'm still sitting at my recent low. I think I'm primed for another drop in the next couple days. Maybe I'll do my trick of dehydrating myself tonight with a little red wine and a very hot bath full of epsom salt. That usually does the trick.

on a really positive note, though, I did gain a notch on my belt this week, and I had a day where I looked in the full length mirror and suddenly noticed that my shape has trimmed down a bit. Those body changes always seem to happen between the scale changes for me, which I find weird, but it happens over and over.

i'm due to titrate up on tirz but i think i will wait a little longer. I'm going to be working my way through the step-up dose vials i have from sdrx for a while. I will crack open the 10mg vial next week or the following, and I'm thinking I'll just stay on the doses that those vials specify. 1 vial of 10mg, then a vial of 12.5mg, then 3 vials of 15mg before i start working on my grey market stash. i saw a discussion on reddit yesterday about staying on minimum effective doses vs. higher weight loss results on higher doses, and my idea for now is to try to get to that 15mg dose in a reasonable time. i'm in it to win it on tirz, and there's some thought out there that weight loss stalls out after a year or so no matter what dose you're on, so make the most of your first year (somewhat speculation but not baseless).

i'm not yet ready to move up on cagri. I want to make sure the fatigue stays away this week. and I also want to assess how the appetite suppression does. last week I felt like the cagri wore off after like 2 days. but its half life is supposed to be longer than tirz, like 9 days. so I was surprised. I'm going to see how the 0.25mg goes this week and probably another week before i think about increasing. if it does seem to wear off after a couple days, maybe a small cagri dose would be a candidate for twice a week dosing. some days i wake up and just want to jab a needle full of some questionable shit into my belly, so maybe i'll double up on cagri if it wears off.

since starting tirz july 15, I'm down 34 pounds. I have something like 25 or 30 to go I would guess. i had a weight loss surgery in 2021 and lost about 110 pounds. right now i'm about 13 pounds above that low point so i'm excited to try to get back to that.
 
Thanks for the updates. I just started .3 mg Wednesday. I take my 15 mg ties on Saturdays and am usually famished by this point in the week. Thursday was rough—I thought I was getting the flu or something—just drank a protein drink and went to bed. Today I feel normal and not particularly hungry. Love it so far!
 
Week 4 Update on tirz10 + cagri 0.25mg

this update is long and rambling, i'll go back and put some of the salient points in bold to save you time, dear reader:


I am pretty sure I wrote an update last week but maybe I forgot to post it. Weird.
This week the tirz 10 seemed even more effective than usual, my appetite was gone Monday - Wednesday. had my usual cycle of tirz side effects that is almost predictable now. insomnia on night one. opposite gastro effects on day 2 and 3. maybe a little aloofness here and there. but nothing too bad.

I thought about skipping the cagri this week since tirz still seemed to be strong. But I went ahead with 0.25mg yesterday. strong appetite suppression so far. Forgot to eat lunch and could only eat a protein cookie for dinner, until after I played a couple hours of tennis, then I was able to fit in a chicken leg and half a deli sandwich.

Still feeling strong suppression today, it's 10am and I just realized I never did my morning protein shake so I am doing that now.

The fatigue on week 3 was much better, and also better starting out on week 4 so far. I was tired at bedtime but not during the day or evening. Hopefully that's going to stay better.

independent testing on my sry cagri 5 came back good. I just contributed to the cost as part of a small group so I don't want to post the coa without their permission, and i'm just slipping this detail into my broader update. but the sry c5 tested good.

i didn't lose any weight on the scale this week...or maybe a half pound depending on which reading you believe. but I didn't gain any either. I'm still sitting at my recent low. I think I'm primed for another drop in the next couple days. Maybe I'll do my trick of dehydrating myself tonight with a little red wine and a very hot bath full of epsom salt. That usually does the trick.

on a really positive note, though, I did gain a notch on my belt this week, and I had a day where I looked in the full length mirror and suddenly noticed that my shape has trimmed down a bit. Those body changes always seem to happen between the scale changes for me, which I find weird, but it happens over and over.

i'm due to titrate up on tirz but i think i will wait a little longer. I'm going to be working my way through the step-up dose vials i have from sdrx for a while. I will crack open the 10mg vial next week or the following, and I'm thinking I'll just stay on the doses that those vials specify. 1 vial of 10mg, then a vial of 12.5mg, then 3 vials of 15mg before i start working on my grey market stash. i saw a discussion on reddit yesterday about staying on minimum effective doses vs. higher weight loss results on higher doses, and my idea for now is to try to get to that 15mg dose in a reasonable time. i'm in it to win it on tirz, and there's some thought out there that weight loss stalls out after a year or so no matter what dose you're on, so make the most of your first year (somewhat speculation but not baseless).

i'm not yet ready to move up on cagri. I want to make sure the fatigue stays away this week. and I also want to assess how the appetite suppression does. last week I felt like the cagri wore off after like 2 days. but its half life is supposed to be longer than tirz, like 9 days. so I was surprised. I'm going to see how the 0.25mg goes this week and probably another week before i think about increasing. if it does seem to wear off after a couple days, maybe a small cagri dose would be a candidate for twice a week dosing. some days i wake up and just want to jab a needle full of some questionable shit into my belly, so maybe i'll double up on cagri if it wears off.

since starting tirz july 15, I'm down 34 pounds. I have something like 25 or 30 to go I would guess. i had a weight loss surgery in 2021 and lost about 110 pounds. right now i'm about 13 pounds above that low point so i'm excited to try to get back to that.
I feel the same about Cagri effects fading away really fast. I’m thinking about upping my dose
 
weird week, neither the tirz 10 or cagri seems to be doing much this week. i upped to cagri 0.3mg this week. side effects down, regular effects down. just one of those weeks i guess.
 
Thank you for the updates!
Feels like a lost week, probably 2 overall for progress. I guess it's part of the journey. But the variability week to week of hunger, appetite, and side effects is weird when it's the same dose

Although sometimes I think our expectations get a little too high. I've felt hungrier this week but still nothing like the before times. I had a fairlife protein shake for breakfast today and it's 10:30 am here and I'm mostly fine. A little hunger sneaking up but that seems normal. On better weeks i would have to force myself to have lunch as well, but not today. It's still much less hunger and food overall than normal meds.
 
Last edited:
Feels like a lost week, probably 2 overall for progress. I guess it's part of the journey. But the variability week to week of hunger, appetite, and side effects is weird when it's the same dose

Although sometimes I think our expectations get a little too high. I've felt hungrier this week but still nothing like the before times. I had a fairlife protein shake for breakfast today and it's 10:30 am here and I'm mostly fine. A little hunger sneaking up but that seems normal. On better weeks i would have to force myself to have lunch as well, but not today. It's still much less hunger and food overall than normal meds.
I understand that sentiment. My first week of Cagri, I did 0.3 and I had a good response with the appetite suppressant. It was fast too, I gave my shot around 6am and by 2pm it kicked in. That was the fastest response I’ve ever had, Sema and Tirz takes about 36hrs on me. But the second week, the 0.3 did nothing, so 3 days later I did another 0.3 and had decent suppression. Now this past week, I did 0.6 in one dose and minimum effects. Oh well, I guess I’ll increase my dose this week again.

I’ve also since stopped my tirz, so this should be interesting LoL
 
Feels like a lost week, probably 2 overall for progress. I guess it's part of the journey. But the variability week to week of hunger, appetite, and side effects is weird when it's the same dose

Although sometimes I think our expectations get a little too high. I've felt hungrier this week but still nothing like the before times. I had a fairlife protein shake for breakfast today and it's 10:30 am here and I'm mostly fine. A little hunger sneaking up but that seems normal. On better weeks i would have to force myself to have lunch as well, but not today. It's still much less hunger and food overall than normal meds.
I really appreciate you sharing your journey with us. Thank you!

Do you find "where" you inject has any correlation to the effectiveness or side effects on Tirz?

I have found that stomach injections provide greater appetite suppression but also increased fatigue. I have only injected in my thighs for the past couple of months but in the thigh there is about three-day delay for me to feel the suppression and day three fatigue is typically the worst.

Based on your experience, I don't think I could add Cagri and make the Tirz fatigue even worse.
 
I really appreciate you sharing your journey with us. Thank you!

Do you find "where" you inject has any correlation to the effectiveness or side effects on Tirz?

I have found that stomach injections provide greater appetite suppression but also increased fatigue. I have only injected in my thighs for the past couple of months but in the thigh there is about three-day delay for me to feel the suppression and day three fatigue is typically the worst.

Based on your experience, I don't think I could add Cagri and make the Tirz fatigue even worse.
I haven't tried the thighs. I did back of the arm last week and it seems to have gone much better than the belly
 
Back
Top