Oh, I was not talking about AmoPure tirz. I was talking about my experience with tirz from a compound pharmacy. My point was that a sting/burn happens with any tirz with certain people. Sting/burn is not uncommon, even with prescription tirz.
Amopure stinging (here we go again)
- Thread starter Fonkymonky
- Start date
Tinygrashopa
New_Member
Love all of my AMO Tirz, Down 21lbs since Aug 26 and no sting at all. Had one issue with pin that the needle bent and caused a bruise. But other than that I love their product.
Thanks! I ordered some as well, waiting for it to ship. Looking forward to the report back.
I started backfilling another syringe because their rubber stopper is a beast haha
Back to add to this discussion. I noticed last week after injection there was a hard bump that stayed for a few days. After this week injection (yesterday) the injection site is sore to the touch and has some redness. It didn't sting initially, this reaction was a few hrs later.
30mg was reconstituted with hospira bac and filtered. When this vial finishes I will try to mix the next one with saline bac water and see if it helps. If it's still causing a reaction I might toss it and take a loss.
30mg was reconstituted with hospira bac and filtered. When this vial finishes I will try to mix the next one with saline bac water and see if it helps. If it's still causing a reaction I might toss it and take a loss.
noteablequotable
Registered
I would quit now. Not sure if you're reacting to the filler or the active ingredient but you shouldn't risk your health.
Injection site reactions are very normal with subq injections. Do a google search for "injection site reaction tirzepatide reddit" and take a look at all of the threads and pics of people getting pretty bad nasty ones from name brand and compounded. People getting permanent discoloring and giant bruised welts from name-brand shots.
With that being said, Amo is the only tirz (out of two compounding pharmacies & amo) to give my rs an ISR. It's mild, a small swollen spot that's red around. Bruises a bit the 2nd day and goes away by the 3rd. Sore if I push down on it, but rs forgets it's there otherwise.
Sounds like we have the exact same ISR Vicki.
I'm not worried about it at all, seems extremely normal from my research.
With that being said, Amo is the only tirz (out of two compounding pharmacies & amo) to give my rs an ISR. It's mild, a small swollen spot that's red around. Bruises a bit the 2nd day and goes away by the 3rd. Sore if I push down on it, but rs forgets it's there otherwise.
Sounds like we have the exact same ISR Vicki.
I'm not worried about it at all, seems extremely normal from my research.
Yes it doesn't seem major. (I've seen worse isr from other peptides for comparison)
I also switched injection sites to the thigh this week so it's possible that could be the issue. I saw the compound formula ingredients do use saline so I'm curious to see if that has any benefit compared to just plain bac water.
I also switched injection sites to the thigh this week so it's possible that could be the issue. I saw the compound formula ingredients do use saline so I'm curious to see if that has any benefit compared to just plain bac water.
I get those lumps from steroids all the time (slightly different since it’s oil, but anyway), just avoid the spot for a while and it will probably be fine
It can be caused by a ton of different things,
Injecting too quickly
Injection into scar tissue or an overused spot
Too large injection size/improper technique
Bacterial infection
Allergic reaction
Most reasons are rather harmless, but if it leaves a lump on every injection I would probably consider tossing it, though personally I would just keep using it unless the lumps are so bad they are annoying somehow
noteablequotable
Registered
I definitely don't mean to be alarmist. I haven't tried the peptides I received from them yet but my experience with them was good, and from what I understand they generally test well.
I am a little alarmed by the fact that I've really only seen ISR reported for Amo, I don't think it's related to any contamination, but I do worry about unidentified allergens because they can quick spiral out of control.
These are all people on compounded/name-brand. Check out some of those pics and reports. It's why I'm not too concerned with my regular sounding isr.
However, I misread Vicki's ISR description, I'm not getting a hard welt like that. That seems weird. I would be concerned with that description.
Mine is just like a mediumish sized bee sting, swollen white and tender/hot to the touch, with redness around it. Gone in ~48ish hours every time.
I'm also wondering if a longer needle is necessary. With other peps I notice less of a reaction with an 8mm needle compared to the 4mm or 6mm. It's very mild I just thought it was worth noting
Mine sounds same as this. It dissappears in a couple of days. It's only noticeable because I've only gotten it with amo. Even the other peptides that I have that sting initially they don't leave a mark the following day.
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noteablequotable
Registered
Yes I understand that there are people outside of the grey market who are experiencing ISRs. If even a small % of those people experienced ISRs it would generate a lot of reports because we are talking about a small percentage of a very large group.
I'm specifically worried about this forum where most users are buying grey market and most reports of ISRs are coming from Amo customers. I would be less worried if we saw a similar number of reports for Nexaph, QSC, or Skye but that does not appear to be the case.
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If I understand what I'm reading, it says something about the solution matching with the body fluids. Could that mean that people will reach differently, depending on how closely the solution matches the body fluids? Meaning, everybody's different?
And, this patent is from 1996. Has this stuff been around for almost 30 years?
Never heard of tonicity. Again, I wonder if this is the reason for the stinging sometimes reported?
Tonicity is a measure of how a solution affects the volume of cells by changing their water content. It's determined by whether a solution is hypotonic, isotonic, or hypertonic:
- Hypotonic: Cells swell due to water entering the cell
- Isotonic: Cells do not change volume because there is a balance of water inside and outside the cell
- Hypertonic: Cells shrink due to water leaving the cell
It might not be a matter of Amo changing their formulation. Could it be differences in individuals?
Tonicity is a measure of how a solution affects the volume of cells by changing their water content. It's determined by whether a solution is hypotonic, isotonic, or hypertonic:
- Hypotonic: Cells swell due to water entering the cell
- Isotonic: Cells do not change volume because there is a balance of water inside and outside the cell
- Hypertonic: Cells shrink due to water leaving the cell
That seems like the date of the journal they're quoting. I see the patent from 2019. (But it wouldn't surprise me if they knew about it for 30 years and never told us too
)Could this explain the stinging you experience?
Tonicity is a measure of how a solution affects the volume of cells by changing their water content. It's determined by whether a solution is hypotonic, isotonic, or hypertonic:
- Hypotonic: Cells swell due to water entering the cell
- Isotonic: Cells do not change volume because there is a balance of water inside and outside the cell
- Hypertonic: Cells shrink due to water leaving the cell
