Day one

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Either way, once it maxes out on effectiveness, there is nowhere to go if you’re already hitting all the receptors.

I can use a rock to push a nail into the board and then switch the better tool to make more progress or I could just use the hammer to begin with. Someday someone will invent a better hammer.

 

[AndyPanda]

I can use a rock to push a nail into the board and then switch the better tool to make more progress or I could just use the hammer to begin with. Someday someone will invent a better hammer.

You could go straight to morphine for pain, but if ibuprofen works, why would you?

 

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You could go straight to morphine for pain, but if ibuprofen works, why would you?

because morphine has terrible side effects? And it's a rare class of drug that does build tolerance.


Reta has LESS side effects than tirz

 

[AndyPanda]

because morphine has terrible side effects? And it's a rare class of drug that does build tolerance.


Reta has LESS side effects than tirz

You are overthinking this and appear to be responding emotionally. Retatrutide works, but If you are maxed out on it, and it’s no longer effective, what is your next option? If you’re on Semaglutide and it stops working, you can go to Tirzepatide. If you are on Tirzepatide and it stops working, you go to Retatrutide. Let’s also not forget that Retatrutide is still not approved for human use. Anywhere.

 

[GLP1Pharmacist]

You are overthinking this and appear to be responding emotionally. Retatrutide works, but If you are maxed out on it, and it’s no longer effective, what is your next option? If you’re on Semaglutide and it stops working, you can go to Tirzepatide. If you are on Tirzepatide and it stops working, you go to Retatrutide. Let’s also not forget that Retatrutide is still not approved for human use. Anywhere.

Low dose Semaglutide or Cagrilintide stack on Retatrutide?

But I do agree in general- Semaglutide then Tirzepatide then Retatrutide if needed. Makes a difference imho if you need to lose 30lbs vs 100+lbs.

 

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You are overthinking this and appear to be responding emotionally. Retatrutide works, but If you are maxed out on it, and it’s no longer effective, what is your next option? If you’re on Semaglutide and it stops working, you can go to Tirzepatide. If you are on Tirzepatide and it stops working, you go to Retatrutide. Let’s also not forget that Retatrutide is still not approved for human use. Anywhere.

I'm definitely not emotional. And you're completely misunderstanding the point. There is no benefit to starting with semaglutide. The only thing you get is slower progress and more side effects.

Your understanding of how it works is just wrong. Starting with Sema and switching to Tirz dosn't give you a greater overall loss than just starting with Tirz.

They aren't additive.

Makes a difference imho if you need to lose 30lbs vs 100+lbs.

It really doesn't make a difference.