Let's talk GLP1's downfall - MUSCLE LOSS

[tul9033]

So you've lost an enormous amount of weight. Have you noticed how much muscle mass you've lost?
Arguably the biggest drawback to GLP-1's is the loss of muscle mass. Many in the healthcare industry are espousing an early death due to GLP-1's rapid weight loss going hand in hand with rapid muscle loss. Older GLP-1 patients losing so much muscle mass they cannot gain back and will no longer be able to support their own body weight as they age.
Let's talk about gaining this muscle mass back. We have some great tools at our disposal: CJC-1295, Ipamorelin, Tesamorelin, GH, ABS.
What are you trying and what have been the results?

 

[chipspew]

I noticed this during my weight loss. Now that I am about 75% of the way to goal, I have started adding weightlifting to my treadmill walking. I have noticed quite an improvement already after about 6 weeks of doing resistance training. Weight loss is going slower, but that's probably a good thing.

Looking forward to find out more about various peptides that can help. Thanks for starting this thread.

 

[scarywood75]

So you've lost an enormous amount of weight. Have you noticed how much muscle mass you've lost?
Arguably the biggest drawback to GLP-1's is the loss of muscle mass. Many in the healthcare industry are espousing an early death due to GLP-1's rapid weight loss going hand in hand with rapid muscle loss. Older GLP-1 patients losing so much muscle mass they cannot gain back and will no longer be able to support their own body weight as they age.
Let's talk about gaining this muscle mass back. We have some great tools at our disposal: CJC-1295, Ipamorelin, Tesamorelin, GH, ABS.
What are you trying and what have been the results?

Ok, first muscle loss is caused by the rapid weight loss and not by GLP1s directly.

Second, GH in my opinion is not worth it given the risks of misuse and what it does to you.

Tesa and IPA would be safer, Enobosarm seems promising as per https://dom-pubs.onlinelibrary.wiley.com/doi/full/10.1002/doi2.109

 

[hexagonal]

So you've lost an enormous amount of weight. Have you noticed how much muscle mass you've lost?
Arguably the biggest drawback to GLP-1's is the loss of muscle mass. Many in the healthcare industry are espousing an early death due to GLP-1's rapid weight loss going hand in hand with rapid muscle loss. Older GLP-1 patients losing so much muscle mass they cannot gain back and will no longer be able to support their own body weight as they age.
Let's talk about gaining this muscle mass back. We have some great tools at our disposal: CJC-1295, Ipamorelin, Tesamorelin, GH, ABS.
What are you trying and what have been the results?

Resistance training and adequate protein intake are enough to stave off muscle loss for most people.

Increasing your IGF-1 might increase the muscle satellite cell proliferation but that won't do much of anything without the resistance training and protein as well.

 

[hexagonal]

Ok, first muscle loss is caused by the rapid weight loss and not by GLP1s directly.

Second, GH in my opinion is not worth it given the risks of misuse and what it does to you.

Tesa and IPA would be safer, Enobosarm seems promising as per https://dom-pubs.onlinelibrary.wiley.com/doi/full/10.1002/doi2.109

Chronically elevated IGF-1 levels from secretagogues will pose the same risks of those levels being reached via exogenous HGH, though.

 

[scarywood75]

Chronically elevated IGF-1 levels from secretagogues will pose the same risks of those levels being reached via exogenous HGH, though.

Yeah of course, all these are just to be taken temporarily

 

[indolent]

spinach

 

[normal]

I hit the gym the whole time I was losing. Best decision.

 

[seeker-seventy-six]

I thought this was a really interesting take on muscle loss with GLP-1s:

2:03:45

Dr. DeFronzo isn’t too worried about lean muscle loss with these meds because, overall, they help people with obesity move more and improve their health in so many ways. The benefits far outweigh the downsides for most people.


Sure, they might not be the best choice for an 80-year-old at high risk for sarcopenia, but for younger people—especially those with prediabetes or type 2 diabetes—these drugs can be game-changers for insulin resistance. As he puts it, food addiction is a huge health concern, and GLP-1s could be a key part of the solution.

 

[keangkong]

So you've lost an enormous amount of weight. Have you noticed how much muscle mass you've lost?
Arguably the biggest drawback to GLP-1's is the loss of muscle mass. Many in the healthcare industry are espousing an early death due to GLP-1's rapid weight loss going hand in hand with rapid muscle loss. Older GLP-1 patients losing so much muscle mass they cannot gain back and will no longer be able to support their own body weight as they age.
Let's talk about gaining this muscle mass back. We have some great tools at our disposal: CJC-1295, Ipamorelin, Tesamorelin, GH, ABS.
What are you trying and what have been the results?

The safest effective supplement for increasing strength is creatine. Pair it wish resistance exercise.

 

[raw_oyster_eater]

Dr. DeFronzo isn’t too worried about lean muscle loss with these meds because, overall, they help people with obesity move more and improve their health in so many ways. The benefits far outweigh the downsides for most people.

yes, most start out morbidly obese and it's important to correct that situation as quickly as possible and get the fat out of the liver. get to a point where you can walk/jog/run.

so i won't be able to lift heavy things as well. so what.

 

[Healthmaster]

Heavy resistance training, high protein diet, testosterone therapy if you are a man, and hgh at therapeutic doses. Muscle will be retained. Starving yourself of course your gonna lose muscle mass, you have to feed the machine.

 

[raw_oyster_eater]

its really impossible to burn fat and gain muscle at the same time or bodybuilders would have figured it out. bodybuilders are either in gain muscle and fat mode or reduce muscle and fat mode.

you can't change the laws of physics captain.

 

[CrabbyD]

its really impossible to burn fat and gain muscle at the same time or bodybuilders would have figured it out. bodybuilders are either in gain muscle and fat mode or reduce muscle and fat mode.

you can't change the laws of physics captain.

If you start with a lot of fat and little muscle, it's very easy to recomposition. The leaner you get the harder it is. I have definitely lost inches without losing pounds when I was 200+

 

[TetsuNW]

One can certainly lose fat and build muscle but there are specific circumstances to doing that. Ones which I believe, from the way people are talking and the reason they're here, would apply to the majority of people here.

This somewhat of a deep dive into the topic but those special circumstances are covered in the first few minutes.

On the subject of resistance training. It's a must imo, not just for GLP1 users, for everyone who wants a long healthy life.

No need for special supplements, eat enough protein 0.6-1g/lb, 0.3g fat per lb, the rest carbs eaten before you train. Start with walking if that's where you are at, add bands, then body weight, then dumbbells or kettlebells, trian 1-2 reps to failure, push a set every so often to failure. Once you feel like you've made some progress then look at getting more serious about resistance training. There are so many various ways to train and implements one can use, it's almost limitless, don't sweat the details, just find what you enjoy and benefit from.

 

[TetsuNW]

A couple playlists to help get you rolling with weights, this applies to any form of resistance training.

Fat Loss Dieting Made Simple

Делитесь видео с близкими и друзьями по всему миру

youtube.com

Hypertrophy Made Simple

Делитесь видео с близкими и друзьями по всему миру

youtube.com

Kettlebells are more advanced from a technique stand point, somewhere in between free weights and Olympic lifting, lmk if you want some info on them.

 

[geoguy78]

I think the whole muscle loss thing is overblown. Yeah, I've lost muscle. But I'm over 60 pounds lighter. I don't need all that muscle anymore to efficiently move my much lighter body around. That muscle developed to support a body that no longer exists. I ski a lot, and can actually ski without getting exhausted. And I've barely worked out since starting tirz.

 

[Mr. Smith]

Don't lose the weight fast... Eat right.. Work out... Gain muscle. I'm saying this after a year on Sema... Lost my weight and in great shape. Lost it SLOW on purpose... I'm talking maybe a 1lb a month slow... (But I only needed to lose 15lbs).

 

[hexagonal]

its really impossible to burn fat and gain muscle at the same time or bodybuilders would have figured it out. bodybuilders are either in gain muscle and fat mode or reduce muscle and fat mode.

you can't change the laws of physics captain.

This is true for bodybuilders, but they also are dieting to extreme levels of bf% for shows. 4-7%. Natural bodybuilders will lose more muscle, enhanced will lose less. And 'muscle memory' lets your body rebuild lost muscle mass pretty quick once you get back into a surplus. AAS are anti-catabolic but when you're going that low it's just basically impossible to not lose some - you might not even be able to get enough protein to begin with in your calorie budget depending on your size.

If you're just starting out and you've got a lot of fat to burn, you can gain muscle in a deficit for a good while - your muscles will just respond very well to stimulus and grow if you have adequate protein intake. After 9-12 months when the noob gains are tapering off it will get harder, and 'recomp' will be easier than building muscle in a deficit, but you'll be able to stay around the same body weight and be dropping fat + adding muscle. But recomp generally isn't as efficient as doing bulk/cut phases, yeah.

One thing to consider, though, is the more muscle, the more calories you burn. The 50 calories per day for a pound of muscle is a myth - you're looking at more like 10ish - but you can put 15-20 lb of muscle in that first year of consistent training, and another 12-15 in the second year with average genetics and no gear. ~300 extra calories a day burned. For men, if you go on TRT and they put you towards the top end of the range, you can do better than this. Women can benefit from TRT too, though generally to a lesser extent than men. I've decided I'd rather go to a much smaller deficit to keep building muscle at a good rate for as long as I can, and when that slows down too much, re-evaluate.

 

[TetsuNW]

I think it's more worthwhile to spend time researching how you can do resistance training than to worry about cut/gain/maintain/maingain/recomp. At the end of the day everyone will have a different situation, 5'2" 60yr 200lb woman is going to have different considerations than a 6' 40yr 250lb man when it comes to potential muscle loss and long term health outcomes.

Can you loss weight without resistance training on GLP-1S, of course. Will you better off long term adding resistance training, also of course.

I'll also add that kettlebells are probably the best methodology for overall health and general physical performance. They do take time to learn the proper form. Dollar for dollar and minute for minute of training they can't be beat, imo.

 

[hexagonal]

I've gotta disagree on the kettlebell thing, unfortunately. Progressive overload is the name of the game when it comes to effective resistance training, and for compound/dynamic movements like those that kettlebells are best at, most people are going to get better results with a barbell, even though it might seem scarier at first, and both have injury potential when used improperly.

You get additional stabilization from a barbell, incremental loading is easier, etc. You're much more likely to get limited by accessory muscles on kettlebell lifts, so you'll be getting the most muscle growth there, because they'll fail first - the primary muscles just aren't going to get as close to failure and as such not get as much growth stimulus.

I'd personally recommend barbells, dumbbells, cables/functional trainers, smith machines, plate/selectorized machines, etc., all as part of a routine before kettlebells.

Of course, doing what you enjoy and you personally find effective is way more important than doing what is "theoretically" best, so if kettlebells are what works for you, no hate there.

 

[Revo39564]

I lost 100 lbs in a little under 6 months and now down 142 lbs in 9 months … was 352 now 210….. lost muscle of course but don’t look like a crack head. Strength and muscle are normal for my weight … I am
Not lifting as much weight either
I had a size 52 waist ,now wear 34-36 “ …… buying large shirts instead of 4-5xl is great. The next phase is weight training to regain some muscle and see if muscle memory is real thing lol…

 

[DwightTheDelight]

I lost 100 lbs in a little under 6 months and now down 142 lbs in 9 months … was 352 now 210….. lost muscle of course but don’t look like a crack head. Strength and muscle are normal for my weight … I am
Not lifting as much weight either
I had a size 52 waist ,now wear 34-36 “ …… buying large shirts instead of 4-5xl is great. The next phase is weight training to regain some muscle and see if muscle memory is real thing lol…

Hell yeah! Good job.

I have a similar story to yours and will be entering rebuild mode here in the next couple of months.

I did do a couple DEXA scans throughout this process though. The first after the first 70lbs lost and another at 160 lbs down. Of those 90lbs lost between the scans, 1 out of every 4 lbs lost was lean mass. Probably not ideal, but I didn't think it was horrible considering I just sat at my work desk and melted for those 9 months. I'm now moving more/casually lifting and can already see a bit of muscle redeveloping. Excited for this next phase.

 

[Revo39564]

Hell yeah! Good job.

I have a similar story to yours and will be entering rebuild mode here in the next couple of months.

I did do a couple DEXA scans throughout this process though. The first after the first 70lbs lost and another at 160 lbs down. Of those 90lbs lost between the scans, 1 out of every 4 lbs lost was lean mass. Probably not ideal, but I didn't think it was horrible considering I just sat at my work desk and melted for those 9 months. I'm now moving more/ casually lifting and can already see a bit of muscle redeveloping. Excited for this next phase.

Yeah, I was thinking about getting a DEXA scan to see how much fat I have…. I was gonna lift weights for six months then have it done

 

[Revo39564]

Hell yeah! Good job.

I have a similar story to yours and will be entering rebuild mode here in the next couple of months.

I did do a couple DEXA scans throughout this process though. The first after the first 70lbs lost and another at 160 lbs down. Of those 90lbs lost between the scans, 1 out of every 4 lbs lost was lean mass. Probably not ideal, but I didn't think it was horrible considering I just sat at my work desk and melted for those 9 months. I'm now moving more/casually lifting and can already see a bit of muscle redeveloping. Excited for this next phase.

Yeah, that’s called the quarter ffm rule….. so you did perfect….

 

[nonyabizznez]

Hell yeah! Good job.

I have a similar story to yours and will be entering rebuild mode here in the next couple of months.

I did do a couple DEXA scans throughout this process though. The first after the first 70lbs lost and another at 160 lbs down. Of those 90lbs lost between the scans, 1 out of every 4 lbs lost was lean mass. Probably not ideal, but I didn't think it was horrible considering I just sat at my work desk and melted for those 9 months. I'm now moving more/casually lifting and can already see a bit of muscle redeveloping. Excited for this next phase.

Yeah but do you look like a crack head? 🤣

I was going for meth head w/o the teeth issues... Got skinny fat guy instead... I'm good with it!

 

[indolent]

Doing (5mg) of Tirz, (500mcg) SLU-PP-332, along with my TRT therapy (200mgTE), down 50lbs since Christmas with minimal fat loss. It’s tough, but you must eat, & often.

Thank you for being honest about your products' effect.

 

[TetsuNW]

I've gotta disagree on the kettlebell thing, unfortunately. Progressive overload is the name of the game when it comes to effective resistance training, and for compound/dynamic movements like those that kettlebells are best at, most people are going to get better results with a barbell, even though it might seem scarier at first, and both have injury potential when used improperly.

You get additional stabilization from a barbell, incremental loading is easier, etc. You're much more likely to get limited by accessory muscles on kettlebell lifts, so you'll be getting the most muscle growth there, because they'll fail first - the primary muscles just aren't going to get as close to failure and as such not get as much growth stimulus.

I'd personally recommend barbells, dumbbells, cables/functional trainers, smith machines, plate/selectorized machines, etc., all as part of a routine before kettlebells.

Of course, doing what you enjoy and you personally find effective is way more important than doing what is "theoretically" best, so if kettlebells are what works for you, no hate there.

Well you're right about a few things. Progressive overload is the name of the game and for muscle growth specifically a barbell is superior. Where you're a bit off the mark is the progression with kettlebells, kbs are going to be mostly about volume. While you can find smaller kbs in 2kg increments micro plate options just don't work well, and magnets don't seem safe to me. It really comes down to volume, mostly increasing reps/sets/ladders or decreasing rest time. Of course you make jumps in KBs too, it's argued the larger jumps make you stronger, idk how I feel about that one though lol.

I want to also make it clear that KB training does build muscle. It's not an optimal implement if your goal is body building type muscle growth. If you want more strength and cardio mixed in, with less chance of injury as the weights are smaller, then KBs should be considered.

If you want to train in a gym you'll have an easier time finding free weights and machines. If you want to train at home in a small space then KBs. From a cost perspective a 12-16-20 or 16-20-24 set of kbs is about the same a single barbell.

Give KB training a go. I was slow to get KB training, it took until I had to move into a studio while my house was being remodeled. I trained on a single 4x6 horse mat I pulled out of storage. Even after the initial ramping up stage the pain free training, mobility, strength, easy recovery and energy I had blew all my years of barbell training out of the water.

I strongly encourage anyone reading all of this nerding out to resistance train. Added on top of the choice you already made for yourself with glp-1s, you will be giving yourself and ypur loved ones the best possible gift of your best self and a longer healthier life.

 

[Revo39564]

Yeah but do you look like a crack head? 🤣

I was going for meth head w/o the teeth issues... Got skinny fat guy instead... I'm good with it!

Skinny guy with lots of extra skin here lol

 

[ruisenor]

So you've lost an enormous amount of weight. Have you noticed how much muscle mass you've lost?
Arguably the biggest drawback to GLP-1's is the loss of muscle mass. Many in the healthcare industry are espousing an early death due to GLP-1's rapid weight loss going hand in hand with rapid muscle loss. Older GLP-1 patients losing so much muscle mass they cannot gain back and will no longer be able to support their own body weight as they age.
Let's talk about gaining this muscle mass back. We have some great tools at our disposal: CJC-1295, Ipamorelin, Tesamorelin, GH, ABS.
What are you trying and what have been the results?

Reta ate my ass. My glutes basically evaporated. 3 months in I increased protein intake and strength training and have gained some muscle mass back, but still have stretch marks on my cheeks..

 

[keangkong]

its really impossible to burn fat and gain muscle at the same time or bodybuilders would have figured it out. bodybuilders are either in gain muscle and fat mode or reduce muscle and fat mode.

you can't change the laws of physics captain.

People often do burn fat and gain muscle at the same time. Whether you can do so depends on the time of shape you're in. People regularly did so while on the TV show the Biggest Loser. Of course, the folks on the show had professional coaches and didn't have any other employment at the time. If you have gone to the gym a few times per week for lifting, losing fat while gaining muscle will be quite hard. If, on the other hand, you've been a couch potato, it becomes quite possible to gain muscle while losing weight. Also, if you start taking steroids (something I don't recommend) while you're losing weight, your ability to lose weight while gaining muscle goes up.

What raw-oyster-eater wrote generally does apply to body builders. My understanding (and I'm not a body builder) is that body builders are always either increasing their weight or reducing their weight. They have to frequently reduce weight so they don't get too fat. While reducing, they exercise to maintain muscle. While gaining weight, muscle size will increase far more with exercise than if a person was exercising while in a calorie deficit or while eating only enough calories to make up what one burns during the day.

 

[Calm Logic]

Older GLP-1 patients losing so much muscle mass they cannot gain back and will no longer be able to support their own body weight as they age.

Oh please. They could always gain the muscle back, just like they do after the trauma of total knee replacement. These healthcare podcasters just need to say something to get attention.

According to Dr. Seed (the peptide guru who is very buff for his age), there is nothing about GLP-1s that makes us lose muscle more than just the effects of dieting. And we have known for 100+ years about muscle loss from dieting.

Dr. Seed is all about cell signaling (to the point he sounds like George in Seinfeld: “Cause it's signals, Jerry, it's signals!”). He says increasing protein intake and doing strength training helps signal to the body to eat fat, not muscle. And 80+ year olds can easily do resistance training:

 

[rkl123]

Oh please. They could always gain the muscle back, just like they do after the trauma of total knee replacement. These healthcare podcasters just need to say something to get attention.

According to Dr. Seed (the peptide guru who is very buff for his age), there is nothing about GLP-1s that makes us lose muscle more than just the effects of dieting. And we have known for 100+ years about muscle loss from dieting.

Dr. Seed is all about cell signaling (to the point he sounds like George in Seinfeld: “Cause it's signals, Jerry, it's signals!”). He says increasing protein intake and doing strength training helps signal to the body to eat fat, not muscle. And 80+ year olds can easily do resistance training:

There’s been some discussion about glucagon itself leading to lower free amino acids. Folks speculate it would make it harder to gain muscle and raise protein requirements. But we don’t really know.

 

[jasonlovespeptides]

Lost 205 lbs in 14 months. I’m sure I lost some muscle but don’t give a damn. I’m skinny AF. I look great. My bloodwork is amazing. I’m successfully maintaining my lowest weight. Benefits outweigh any muscle loss negatives. If I wanted slow and steady weightloss I would have spent less money and gone to WW to lose a few lbs a month

 

[tul9033]

Oh please. They could always gain the muscle back, just like they do after the trauma of total knee replacement. These healthcare podcasters just need to say something to get attention.

According to Dr. Seed (the peptide guru who is very buff for his age), there is nothing about GLP-1s that makes us lose muscle more than just the effects of dieting. And we have known for 100+ years about muscle loss from dieting.

Dr. Seed is all about cell signaling (to the point he sounds like George in Seinfeld: “Cause it's signals, Jerry, it's signals!”). He says increasing protein intake and doing strength training helps signal to the body to eat fat, not muscle. And 80+ year olds can easily do resistance training:

It's cause and effect. Not that the GLP-1's are directly responsible for muscle loss other than rapid weight loss and the associated muscle loss.

 

[Calm Logic]

There’s been some discussion about glucagon itself leading to lower free amino acids. Folks speculate it would make it harder to gain muscle and raise protein requirements. But we don’t really know.

And there's speculation that the GLP-1s help preserve muscle during weight loss, such as by reducing inflammation and insulin resistance.

 

[Calm Logic]

It's cause and effect. Not that the GLP-1's are directly responsible for muscle loss other than rapid weight loss and the associated muscle loss.

In that case, I say we start having virtual pizza parties 😀

I do wonder how internalized fat stigma may contribute to people losing weight too fast (by upping the dose to accelerate reaching an arbitrary/cultural standard). But the fear of sagging skin slows me down more than anything, more so than potential muscle loss.

 

[tul9033]

In that case, I say we start having virtual pizza parties 😀

I do wonder how internalized fat stigma may contribute to people losing weight too fast (by upping the dose to accelerate reaching an arbitrary/cultural standard). But the fear of sagging skin slows me down more than anything, more so than potential muscle loss.

Oh for sure, obesity is as much of a mental illness as anything.
Luckily, I've never really struggled with my weight. I mainly got into this for my family members. I did and do take low doses of Tirz mainly for the inflammation effects. I was about 10-15 #'s over my goal weight last year and got up to 3 mg of Tirz. It was shocking how I had to force myself to eat. Others in my family have lost over 40 #'s and the bat wing arms are real! I do notice the loss of muscle mass in the high # losers.

 

[Calm Logic]

"Patients were able to lose fat mass with only a minimal decline in muscle mass":

Weight loss: Study finds keys to minimize muscle loss from GLP-1 drugs

People taking GLP-1 drugs can decrease fat mass while minimizing muscle loss with a few key strategies that include proper supervision, and a protein-rich diet, the results of a new study suggest.

www.medicalnewstoday.com

Women lost an average of 10.8 kg of fat mass while only losing 1.4 pounds (0.63 kg) of muscle.

Men experienced a fat mass reduction of 25 pounds (12 kg), with a minimal muscle loss of just 2.4 pounds (1 kg)

Sticking to the medication, eating enough protein, and having regular check-ups seemed to lead to better results...

"The main things patients can do is ensure adequate protein intake and exercise. Resistance-type exercises are helpful in maintaining and possibly even building muscle"

 

[Bunny]

I am a 75 year old female and was lifting heavy for years before I lost weight. I intend keeping it up. I think everyone should be lifting when on a glp1 , particularly more mature people.

 

[Lullabytreehugger]

Just get on test + tren and deca. Tren will help with nutrition partition, deca will bulk you up and regain any lost muscle mass. For this reason alone, we should be on test and GLP1s at same time to avoid as much muscle loss we can save.

Or another way is cut down first, as much weight as u can, then after get on the gear and start building muscle again. Say you gained 15kgs of muscle mass over a 12 week cycle.

Naturally once you stop test you will lose some muscle gains. From that 15kgs gained you might lose 5kgs.

So you will still be ahead 10kgs.

Also keep in mind muscle eats glucose so in theory after your cycle your blood sugar should be lower than before and it will help with keeping fat gain to a minimum.

 

[miche52]

So you've lost an enormous amount of weight. Have you noticed how much muscle mass you've lost?
Arguably the biggest drawback to GLP-1's is the loss of muscle mass. Many in the healthcare industry are espousing an early death due to GLP-1's rapid weight loss going hand in hand with rapid muscle loss. Older GLP-1 patients losing so much muscle mass they cannot gain back and will no longer be able to support their own body weight as they age.
Let's talk about gaining this muscle mass back. We have some great tools at our disposal: CJC-1295, Ipamorelin, Tesamorelin, GH, ABS.
What are you trying and what have been the results?

Started using compound sema in Jan 2023. Loss 30 pounds over 10 months. Already was a cardio head but made it a point to start lifting because I could tell I was losing strength at 49. I didn't go beyond 1.0 mg. After my weight stalled, I thought maybe this is where my body wants to be so I stayed in maintenance for a year and spreading dosing every 10-14 days. 5 weeks ago I switched to tirz and now losing again. My goal is to lose another 20 pounds. I see the benefit of losing slow as I don't want to sacrifice losing too much muscle. At 51, in perimenoupase this is no joke. All the years of yo yo dieting created a lot of havoc on the body.

 

[hexagonal]

Just get on test + tren and deca. Tren will help with nutrition partition, deca will bulk you up and regain any lost muscle mass. For this reason alone, we should be on test and GLP1s at same time to avoid as much muscle loss we can save.

Or another way is cut down first, as much weight as u can, then after get on the gear and start building muscle again. Say you gained 15kgs of muscle mass over a 12 week cycle.

Naturally once you stop test you will lose some muscle gains. From that 15kgs gained you might lose 5kgs.

So you will still be ahead 10kgs.

Also keep in mind muscle eats glucose so in theory after your cycle your blood sugar should be lower than before and it will help with keeping fat gain to a minimum.

You're not putting on 15kg of muscle on a 12 week cycle. Actual retained muscle mass gains on cycle is much closer to 1lb/week, and that's assuming dialed in training, diet, and recovery. 10kg retained would be elite genetics on very high doses levels of gains.

Test at TRT levels is extremely anti-catabolic by itself. You don't need to run a cycle while losing weight to retain muscle, and running more than TRT levels of AAS while overweight is a recipe for all sorts of negative health impacts.

 

[Calm Logic]

Fava beans as a great source of muscle-building aminos and peptides:

Plant-based peptides from fava beans to shake up muscle health segment

08 Feb 2023 --- Extracting bioactive peptides from fava beans using precision tech as a “game-changing” muscle health solution, Nuritas and Maastricht University have published a clinical trial demonstrating the effectiveness of the company’s plant-based bioactive peptide solution, PeptiStrong.

www.foodingredientsfirst.com

Extracting bioactive peptides from fava beans using precision tech as a “game-changing” muscle health solution, Nuritas and Maastricht University have published a clinical trial demonstrating the effectiveness of the company’s plant-based bioactive peptide solution, PeptiStrong.

The study, published in the Journal of Nutrition, shows that the bioactive ingredient performs better than traditional animal proteins, specifically milk protein, in muscle conditioning. Nuritas’ PeptiStrong increases muscle synthesis recovery following immobilization.

Faba Bean: An Untapped Source of Quality Plant Proteins and Bioactives - PMC

Faba beans are emerging as sustainable quality plant protein sources, with the potential to help meet the growing global demand for more nutritious and healthy foods. The faba bean, in addition to its high protein content and well-balanced amino ...

pmc.ncbi.nlm.nih.gov

Faba beans are emerging as sustainable quality plant protein sources, with the potential to help meet the growing global demand for more nutritious and healthy foods. The faba bean, in addition to its high protein content and well-balanced amino acid profile, contains bioactive constituents with health-enhancing properties, including bioactive peptides, phenolic compounds, GABA, and L-DOPA. Faba bean peptides released after gastrointestinal digestion have shown antioxidant, antidiabetic, antihypertensive, cholesterol-lowering, and anti-inflammatory effects, indicating a strong potential for this legume crop to be used as a functional food to help face the increasing incidences of non-communicable diseases.

 

[nonyabizznez]

For the bean less educated (me):

Faba and Fava are the same bean! 🫛

The more you know 🌈

 

[Calm Logic]

Also known as "haba" beans in the Mexican food section of Walmart. Lots of online Mexican recipes for fava bean soup (sopa de habas).

 

[nonyabizznez]

Also known as "haba" beans in the Mexican food section of Walmart. Lots of online Mexican recipes for fava bean soup (sopa de habas).

Also known as "vaba" beans is you're one of the Gabor sisters.
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