Orforglipron: The next big thing?

[Habibibi]

That was not the issue for me. The split tablets seemed to work just as well.

Orfo itself is stomach resistant: "Orforglipron is inherently resistant to stomach acid and does not require a protective coating to remain effective" (Gemini). I may find an article later.

Still other concerns though, more in theory than anything else. Like one side of the tablet may be stronger than the other.

Seems like that depends on who's manufacturing the pill. I have no doubt that the above is true if Lilly is the manufacturer. I'm less convinced this is the case for gray vendors.

 

[Calm Logic]

The third/last phase of the orfo trial used 1 mg as a starting dose. Phase two used mostly 3 mg as the starting dose, with more GI side effects.

But the smallest dose available in grey is 6 mg, and some resellers like PGB only sell 12 mg (tested at 13.7 mg). Uther has 8 mg (tested at about 9 mg) and 12 mg (tested at about 13 mg). WWB has 6 mg but no testing available.

 

[Jellybelly54]

Found 6mg caps . 90 capsule for $185 at The Peptique. US company in TX. Fast shipping.