Orforglipron: The next big thing?

Novo Nordisk is working on a pill form of Semaglutide using their "SNAC" technology. The recent news about Amycretin was also encouraging, although still in early trials. I agree that pills will be the preferred method of administration for most people. This would mean easier production, distribution and storage. Unfortunately, I am less optimistic that Novo or Evil Lilly would charge any less for the pills. We need competition from more companies, not just a different form of the medication.

If the drug costs less to make , store , transport and distribute the price will be lower. More so if there are multiple oral drugs on the market. In fact they may be able to make MORE money charging less. The vast majority of Americans aren’t able to afford the current price structure. 50% profit levels on 10 sales are a lot better than 200% profit levels on 1.


There are 104 million obese Americans. And 86 million overweight. Around 15 million are on glp 1 drugs ( legit scripts ) currently. The drug companies could sell a LOT more at a lower price point. And they are going to have to in a few years when patents expire.
 
If the drug costs less to make , store , transport and distribute the price will be lower. More so if there are multiple oral drugs on the market. In fact they may be able to make MORE money charging less. The vast majority of Americans aren’t able to afford the current price structure. 50% profit levels on 10 sales are a lot better than 200% profit levels on 1.


There are 104 million obese Americans. And 86 million overweight. Around 15 million are on glp 1 drugs ( legit scripts ) currently. The drug companies could sell a LOT more at a lower price point. And they are going to have to in a few years when patents expire.
Agreed. Over time the prices will fall. Granted I’m not paying much now thanks to Chinese vendors.
 
No thanks to a pill form of anything. I have to think about my tirz once a week for about five minutes, and then I get to just go about my business. If I could stick my thyroid medicine, my vitamins, and all my other meds into a syringe, do it once a week, and spend the whole rest of the week never trying to remember to go swallow a pill, I'd be thrilled.
 
No thanks to a pill form of anything. I have to think about my tirz once a week for about five minutes, and then I get to just go about my business. If I could stick my thyroid medicine, my vitamins, and all my other meds into a syringe, do it once a week, and spend the whole rest of the week never trying to remember to go swallow a pill, I'd be thrilled.
I'm not sure I actually prefer an injection to pills, however, I don't mind injecting myself enough to tolerate worse results with pills. I do realize that large numbers of folks do have problems with injecting themselves. I though I had a problem with injecting myself too as I spent about an hour preparing to inject myself for the first time. Then I injected myself. It was actually rather funny; after all that worry, it turned out to be nothing (for me).
 
I though I had a problem with injecting myself too as I spent about an hour preparing to inject myself for the first time. Then I injected myself. It was actually rather funny; after all that worry, it turned out to be nothing (for me).
GIRL SAME! (or boy same) SO SAME! I thought it was gonna hurt, gonna be scary, gonna be complicated, and then "Oh. Now I'm done? for a WEEK???"
 
I had nightmares about stabbing myself after my first injection. I kinda like pinning myself now. I also had nightmares when I first got contacts. I still don't really like putting those in and taking them out.
 
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