Sleeping well but waking up once a night…

Sumblime81

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Anyone else going through this on Reta? Seems like no matter how tired I am, I’m always waking up once per night. I don’t have any issues getting back to sleep, yet it’s still kind of annoying.

Looking for some solutions. I kinda like sleeping throughout the night.

Thank you
 
I was waking up a couple times per night, but after a few weeks its mostly resolved.
 
I was waking up a couple times per night, but after a few weeks its mostly resolved.
I’ve heard that, but I’m on my third month. It used to be worse in the beginning. It has tapered off considerably, but it’s still once a night. It’s not the worst thing in the world and definitely worth it.
 
I’ve heard that, but I’m on my third month. It used to be worse in the beginning. It has tapered off considerably, but it’s still once a night. It’s not the worst thing in the world and definitely worth it.
Truth is I usually got up once a night before to use the bathroom, so that's kinda normal for me.
 
I was waking up a couple times per night, but after a few weeks its mostly resolved.
I’ve heard that, but I’m on my third month. It used to be worse in the beginning. It has tapered off considerably, but it’s still once a night. It’s not the worst thing in the world and definitely worth it
Only once? You're lucky. I wake up at midnight, 1 or 2 and can't go back to sleep for shit. I end up getting out of bed at 4-4:30 every damn morning. This started on the last few doses of 6mg and now at 8mg, it's terrible.
Yeah, there’s that too, the whole 4:30 thing. I can’t sleep past then. Even if I stay up late, I can’t. Makes the rest of the day kinda suck.
 
Yeah, there’s that too, the whole 4:30 thing. I can’t sleep past then. Even if I stay up late, I can’t. Makes the rest of the day kinda suck.
I sure does, doesn't matter how late I stay up, and am usually so tired I can't. Some afternoons I need to sleep some, and I hate napping. At least I know what's on the TV at 4:30, and get caught up on the 3 forums I on, and my TG groups. This is the only one with this GLP-1 subject.
 
Once a night? Youngsters. I got up three times a night before Reta and I still get up 3 times a night 10 weeks into Reta. The difference is that before Reta,I could fall back asleep in a couple minutes after the walk to the toilet. Now it takes me 30m to an hour every.time. Oh and my deep sleep got trashed.

Still looking for new things to try. I've tried almost everything suggested here so far except ashwaganda and epithalon. Glycine, melatonin, and magnesium seem to help. Nothing else for me.
 
Once a night? Youngsters. I got up three times a night before Reta and I still get up 3 times a night 10 weeks into Reta. The difference is that before Reta,I could fall back asleep in a couple minutes after the walk to the toilet. Now it takes me 30m to an hour every.time. Oh and my deep sleep got trashed.

Still looking for new things to try. I've tried almost everything suggested here so far except ashwaganda and epithalon. Glycine, melatonin, and magnesium seem to help. Nothing else for me.
I’m wondering if anyone has used Tesa or hgh and that helped out. If so, I’d like to give that a go. I just want to sleep well again. I also have sleep apnea but that has gotten better since losing weight, but it might still be the issue. I have an appointment this week for the sleep apnea. Hopefully, it helps.
 
Would be easier if you said "M/F" ; over or under 50...

Do you just wake up, or do you wake up to go to the bathroom? Do you live in an urban or rural area? Have there been any changes in your environment, such as a new road or a data center?

Have you checked your blood sugar recently? Your prostate? (hence the m/f?)

There are many ridiculous beliefs that lead many people to take drugs to help them sleep. Waking up during the night isn't necessarily a sign of a health issue, quite the contrary.

It is important to remember that in the preindustrial era, when there was little artificial lighting, the norm was a two or three phase sleep pattern. People spoke of a “second sleep.” There were social activities in the middle of the night. Artisans were working. Some renowned authors and scholars of the Middle Ages and the Enlightenment wrote in the middle of the night and have testified to this.

So, you may very well have had a good sleep in the first part of the night, and your body had gotten enough at that point.
A little reading, doing the accounts, polishing your shoes, batch cooking, stargazing… a small, pleasant or boring activity, and then you go back to bed for one or two sleep cycles.
Add a 10 to 20 minute nap after lunch, and you’ll be in top form.
 
Is THAT your dog???? Asking because I too own a snuggling, snuffling wrinkle monster.
 
I’m wondering if anyone has used Tesa or hgh and that helped out. If so, I’d like to give that a go. I just want to sleep well again. I also have sleep apnea but that has gotten better since losing weight, but it might still be the issue. I have an appointment this week for the sleep apnea. Hopefully, it helps.
51M here. Both CJC/Ipa and HGH have helped me get better sleep. I was already getting pretty good sleep before, but now even better.

I start my bedtime routine at the same time every night too, which is important for consistently good sleep.
 
Im not taking anything and still frequently wake up 2-3 times a night typically getting 4-6 hours of sleep. Reta (or other glp) are not my main interest with peptides, but I am still interested in them and knowing it can disrupt sleep kinda concerns me from starting to take it when I already dont typically get great sleep to begin with. im kinda wondering what might be best to stack with it help with sleep but since im not looking to start it now ill cross that bridge when I get to it. Im thinking if I did start reta I would likely be taking some GH compound with it because muscle retention would be a priority and Im wondering if the GH might help with sleep as well. It would be nice to kill 2 birds with 1 stone.
 
I never wake up at night. Which is weird considering my history of sleep issues. I had really bad insomnia for many years, where I'd always wake up at 2-3am and could not go back to sleep.

Then, because of that pattern, I started intentionally trying to do biphasic sleep. So I'd go to sleep at 10pm and set an alarm for 2am. At 2am I'd get up for 2 hours and go back to sleep at 4am and then set my alarm and wake up again at 8am. This seemed to help a lot.

Fast forward until now. I have sleep apnea, diagnosed by 2 sleep studies. I was about 20-30 lbs overweight when I did both of those. Then I got 60 lbs overweight and now am back to 30 lbs overweight.

Odd thing is that I NEVER wake up after going to sleep, no matter if I sleep 5-6 hours or 8 hours, I do not wake up. Apparently I am stopping breathing during that time, but it does not wake me up. I just get up and am already tired because apparently my sleep is garbage because of the apnea, but I don't wake up and I have dreams. I will pee first thing I wake up, but that doesn't awaken me from sleep.

There is actually a FDA approved drug for sleep apnea. It's called Tirzepatide. Was sort of funny when my Dr mentioned my apnea recently, probably weeks after I was already on Tirz. I said 'there's this drug, maybe we should try it'. Hopefully it helps.

I have a lifetime supply of Ambein from all of those years of insomnia because I rarely ever took it. It doesn't help my sleep and it makes me feel more lethargic when I wake up. I also don't get any of the fun experiences from Ambien like going shopping and buying big screen TVs at 3am and not remembering any of it. So Ambien sucks.
 
Anyone else going through this on Reta? Seems like no matter how tired I am, I’m always waking up once per night. I don’t have any issues getting back to sleep, yet it’s still kind of annoying.

Looking for some solutions. I kinda like sleeping throughout the night.

Thank you
Mag Gly is the way.
 
Totally normal, even without peptides. I don't readily post AI-generated 'splanations, but here:


Gemini AI Overview

The average number of nighttime urinations increases steadily with age. While waking up 0 to 1 time per night is considered normal for most adults, this frequency generally shifts upward as men get older due to changes in kidney function, hormone production, and bladder capacity.

Typical Nighttime Urination by Age (Male)
  • Ages 20–40: The average is 0 to 1 time per night. About one-third of men in this bracket wake up at least once to use the bathroom.
  • Ages 45–60: The average is 1 time per night. Waking more than once generally begins to exceed the normal range for this age group.
  • Ages 65–70+: The average is 1 to 2 times per night. Over 70% of individuals in this age bracket experience at least one instance per night, and up to 60% of people over 70 wake up two or more times.
When to Seek Advice
Waking up more than once per night is clinically referred to as nocturia. If nighttime urination is disrupting your sleep or happens more than twice a night, it may point to underlying factors like an enlarged prostate (BPH), nocturnal polyuria, or sleep apnea.
 
51, I get awsome sleep. But I do get up at least twice a night to pee. Prostate is good .4 psa on my last bloodwork. I just drink a ton of water a day.
 

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