SS-31 protocols?

[Peloma]

I have not read up too much on serotonin syndrome, but it sounds like no fun from what I have read.

I feel like I had some of that when I over dosed myself with Selank (probably why I was gun shy with mixing it with blue). I felt uncomfortable and withdrawn. My head was in a strange place.

Do not pin more than 1mg if you are pep sensitive.

 

[Skidude]

I was introduced to a great website about 10 years ago, I have been a fan ever since!
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I have since shared it with many of my friends and would like to share it here.
This is a great subject to introduce Kurzgesagt to you all on as this video covers a few things relatable and important to us.
I am also taking this opportunity to adjust, maybe temporarily, my ava.

 

[Calm Logic]

I love the zombie metaphor for senescent cells. That helps a lot.

 

[Calm Logic]

After looking at many different options my first cycle was 4mg 5days on 2 days off for 6 weeks.
I am now ready for my next and will be stacking with overlaps as well- SS-31, Mots-C, NAD+
This is my current SS-31 protocol- Going with Basic first. 5mg a day also taking CoQ10,TMG,Lipo-c w/b12

Basic SS-31 Cycle (General Health & Mitochondrial Support)

Dosage: 5-10 mg subcutaneous (SQ) daily

Duration: 6-8 weeks

Break Between Cycles: 6-8 weeks off

Considerations:

Take on an empty stomach for better mitochondrial uptake.

Pair with Lipo-C, B12, or CoQ10 for enhanced mitochondrial function.

Combine with low-impact exercise (walking, bodyweight training) for best results.

Advanced SS-31 Cycle (Athletic Recovery & Performance)

Dosage: 10-20 mg SQ daily

Duration: 8-12 weeks

Break Between Cycles: Equal to cycle length (8-12 weeks)

Additional Support:

Lipo-C/B12 injections for metabolism & energy.

Creatine, TMG, and CoQ10 for added mitochondrial support.

Cold therapy or sauna use to enhance mitochondrial function.

Optional: Microdosing Approach (for Longevity & Maintenance)

Dosage: 5 mg SQ 3-4x per week

Duration: Ongoing with periodic breaks

Breaks: 2-4 weeks off every 3 months

More info regarding dosing (from Reddit):

https://www.reddit.com/r/Peptides/comments/ib5t2n/comment/g2ipeqf

 

[Peloma]

More info regarding dosing (from Reddit):

I find that one hard to believe.

 

[Calm Logic]

I find that one hard to believe.

Yes, but I have no choice but to believe something positive about micro-dosing (which is what 4 mg daily would be compared to 40 mg daily). I have only 100 mg total from SRY

 

[Peloma]

Yes, but I have no choice but to believe something positive about micro-dosing (which is what 4 mg daily would be compared to 40 mg daily). I have only 100 mg total from SRY

Definitely not a knock against you, or the benefit of taking a 4mg dose vs 40mg. I just don't see how every source is quoting the same, flawed study and they're like, "we're good with this..."

 

[Skidude]

More info regarding dosing (from Reddit):

https://www.reddit.com/r/Peptides/comments/ib5t2n/comment/g2ipeqf

I would love to see more of this that was not 5 years old, I have seen most cycles start at 4mg 5/2 dosing.
My second I am doing 5mg 5/2

 

[Super Trips]

Yes, but I have no choice but to believe something positive about micro-dosing (which is what 4 mg daily would be compared to 40 mg daily). I have only 100 mg total from SRY

40mg would prolly make you superman i think 4-10mg tops would be good enough

 

[Calm Logic]

By @GimmeABreak, an interesting experience with SS-31, with more energy than MOTS-c:

I didn't notice much additional weight loss with SS31 after pinning for 2-3 months. For the first two-months I had great energy/focus from it, but can't really say it helped with weight or body composition.

I did notice some fat loss (maybe not weight, but belly fat) with MOTs-C. I didn't notice any energy increase with it but my waist size went down. This could have been from the Tirz but I think the MOTs played a role in it.

After a couple of months SS31 stopped giving any feels, even pinning a full 34mg vial (in 2 doses) on the same day, so I am taking a break for a month or two. I can't wait to revisit it and hope I get the feelz back.

Hard to say, I don't get a lot of "feelz" from most of the peps I mentioned. NAD+ (not a pep) maybe a little bit of energy but no rush like others report. SS31 was great at first, I guess I am optimized now so I really don't get much from it or MOTs-C.

Might want to consider adding a TMG supplement 30-60 minutes prior to NAD+ pin. It makes sure you have enough methyl donors to supply the NAD+. I take 1000mg 2x a day when taking NAD+, SS31 or MOTs-C.

 

[Skidude]

By @GimmeABreak, an interesting experience with SS-31, with more energy than MOTS-c:

ss-31 energy is anecdotal..
However, the "feeling" is real.
But only you get it.

 

[Peloma]

ss-31 energy is anecdotal..
However, the "feeling" is real.
But only you get it.

True. I just finished my first kit of SS-31, and definitely got feels early on. They dissipated, but the positive energy was still there.

Side note: Mots-c stings as advertised.

 

[Calm Logic]

The International Peptide Society is recommending 200 mg per day???

They certainly seem to be:

SS-31 - The International Peptide Society

SS-31 Szeto-Schiller-31 Elamipretide MTP-131 Bendavia SBT-272 Mitochondrial Antioxidant Support Contents Sequence: D-Arg-Dmt-Lys-Phe-NH2 Molar Weight: 639.8 g/mol Molecular Formula: C32H49N9O5 Most Frequent Uses: Mitochondrial support Neuroinflammation Memory/cognitive support Mitochondrial...

peptidesociety.org

• SubQ dosage:
  • Supplied 100mg/ml
  • 2ml SubQ daily x 4 weeks

 

[Calm Logic]

ss-31 energy is anecdotal..
However, the "feeling" is real.
But only you get it.

And MOTS-c is banned by the World Anti-Doping Agency (WADA), unlike SS-31. So I assume that is more evidence that MOTS-c would potentially provide more of a boost than SS-31.

 

[Peloma]

The International Peptide Society is recommending 200 mg per day???

They certainly seem to be:

SS-31 - The International Peptide Society

SS-31 Szeto-Schiller-31 Elamipretide MTP-131 Bendavia SBT-272 Mitochondrial Antioxidant Support Contents Sequence: D-Arg-Dmt-Lys-Phe-NH2 Molar Weight: 639.8 g/mol Molecular Formula: C32H49N9O5 Most Frequent Uses: Mitochondrial support Neuroinflammation Memory/cognitive support Mitochondrial...

peptidesociety.org

That would get expensive real fast. The most i took in this last cycle was 10mg. I didn't feel any increased benefit, but that's how these things work. Most of the benefit is in the background.