Will anything ever bring the early magic back?

[Sunflower]

50mg. We'll see. The Wellbutrin was supposed to be for nicotine which didn't work but it turned out it did wonders for my mood when used with buspirone. The sema helped with the nicotine, I'm using almost none now it's mostly habit. I only just started it so I have no opinion on the nal yet, so far sema worked for alcohol by like 90%.

I honestly don't know, my pharmacy just kept not filling it for like five months then when my psych sent in a 90 day script instead now that she considers me Stable and Trustworthy (tm) all of a sudden they had it. I probably should have asked why, I would have happily just paid for it cash, I had to do that last year when my insurance wouldn't cover lamotrigine in anything less than 90 day supply.

WTF, like what do they think someone’s gonna do that’s dangerous/ shady with Naltrexone But yeah, I can empathize with the challenge of having to build “trust” with your psych. I’ve met all kinds of ignorant ones, but my current one is a psychedelic ketamine psychiatrist in Vermont (teleheath) so he’s surprisingly open minded!

Please keep us posted on your Nal experience—I am thankful Tirz fixed the food addiction, but struggling with residual mental “sticky/ disempowering thought” addictions and…Reddit. It seems like you’ve overcome 90+% of the physical dependencies, which is incredible.

 

[chmuse]

WTF, like what do they think someone’s gonna do that’s dangerous/ shady with Naltrexone But yeah, I can empathize with the challenge of having to build “trust” with your psych. I’ve met all kinds of ignorant ones, but my current one is a psychedelic ketamine psychiatrist in Vermont (teleheath) so he’s surprisingly open minded!

Please keep us posted on your Nal experience—I am thankful Tirz fixed the food addiction, but struggling with residual mental “sticky/ disempowering thought” addictions and…Reddit. It seems like you’ve overcome 90+% of the physical dependencies, which is incredible.

I'm bipolar and I started seeing them because I was unmedicated and having a hypomanic episode (looking back, I think I may have been actually manic and just not well enough to see it- just poorly enough to know I wasn't feeling RIGHT) so it makes sense they wanted me seeing them every month until I was stable. Then the first one stopped taking my insurance, and the second one sent me to another new psych when I asked for antabuse because she considered me a seizure risk (I wasn't, to be clear...) then another insurance issue.... I've finally been with one long enough to go to every three months for appointments. I saw the same woman for seven years in my early twenties and I despised her, but that continuity of care was nice, looking back.

I'm now on nal, sema, AND cagri. I'm doing pretty damn great, but I can't tell you which of the three to attribute that to. Drinking also stops my weight loss progress, so having a concrete goal and consequences is helping. Drinking = sema no workie = no drinkie for ChMuse. From what I've seen sema seems best for those addictive behaviors (I've actually cut down on Reddit and TikTok by miles, I've read four books so far in January.)

 

[clayd]

I'm bipolar and I started seeing them because I was unmedicated and having a hypomanic episode (looking back, I think I may have been actually manic and just not well enough to see it- just poorly enough to know I wasn't feeling RIGHT) so it makes sense they wanted me seeing them every month until I was stable. Then the first one stopped taking my insurance, and the second one sent me to another new psych when I asked for antabuse because she considered me a seizure risk (I wasn't, to be clear...) then another insurance issue.... I've finally been with one long enough to go to every three months for appointments. I saw the same woman for seven years in my early twenties and I despised her, but that continuity of care was nice, looking back.

I'm now on nal, sema, AND cagri. I'm doing pretty damn great, but I can't tell you which of the three to attribute that to. Drinking also stops my weight loss progress, so having a concrete goal and consequences is helping. Drinking = sema no workie = no drinkie for ChMuse. From what I've seen sema seems best for those addictive behaviors (I've actually cut down on Reddit and TikTok by miles, I've read four books so far in January.)

Very interesting story thanks for sharing.

Everyone said tirz curbed their drinking and it didn't change mine at all, but since I started in on the cagrisema, I have cut back, now that I think about it. Maybe sema is helping some there. It would be welcome assistance.

Naltrexone never seemed to really help me much but it did make me throw up all the time. Doc said that should subside but it never seemed to.

Glad you are in a better place @chmuse

 

[chmuse]

Very interesting story thanks for sharing.

Everyone said tirz curbed their drinking and it didn't change mine at all, but since I started in on the cagrisema, I have cut back, now that I think about it. Maybe sema is helping some there. It would be welcome assistance.

Naltrexone never seemed to really help me much but it did make me throw up all the time. Doc said that should subside but it never seemed to.

Glad you are in a better place @chmuse

Sorry for derailing Don't tell Yoyo.

Everything I've seen is that sema hits that receptor hardest and it seems to be the one that's helping with addictive behaviors. I think someone posted a chart saying survo and maz also work similarly? Sema is the one in active research for addiction medication, anyway. There's entire subreddits for it.

A lot of people seem to react to nal that way, which I think is part of why the Sinclair Method works.

 

[Umm.okay]

I started Tirz in July 2024 and it's been a successful ride so far. I am still losing, or not gaining, albeit slowly. Lost 45 pounds and about 15 or 20 to go.

I've stayed at 12.5mg till now, and I'm ready to go to 15mg on my next dose. But i've also been stacking cagri or cagrisema on day 5 of the tirz cycle to mitigate hunger.

The issue is that I just don't get the feels like I used to. I don't get the feeling that I'm full after a small portion, I don't get the food aversions or just absolute disinterest in snacking, and I don't get the ability to chug a protein shake for breakfast and forget about food until dinner.

I know there's a lot I could do. I can increase my dose a little, or take it more frequently. I can stack more cagri or sema or survo, I can transition to or stack reta...lots of options.

But what I really wonder is, is there any way to bring back the magic of those first couple months. I loved those days where I could just not think about food for 12 hours straight. Even when I increase my dose or stack, it doesn't seem to be the same.

Honestly it's not surprising to me that people start getting caught up in the suspicion they got a bad batch or a bad vial, or it's degraded or whatever. I don't think those things have happened to my products most likely, but I see why people think it. After some time, it just doesn't feel the same.

Is there any way to bring the magic back?

Hi there! I’m fairly new to all of this but just read a very interesting article that explains the plateaus in out weight loss journey and thought maybe it could help you.

Good luck in your journey!

file:///var/mobile/Library/SMS/Attachments/fd/13/2275B90E-AF75-4E8B-AF57-8CBE6187E294/Tirzapatide_The_Missing_Manual_v_0_95_20230901_Compressed_1.pdf

 

[Sunflower]

I'm bipolar and I started seeing them because I was unmedicated and having a hypomanic episode (looking back, I think I may have been actually manic and just not well enough to see it- just poorly enough to know I wasn't feeling RIGHT) so it makes sense they wanted me seeing them every month until I was stable. Then the first one stopped taking my insurance, and the second one sent me to another new psych when I asked for antabuse because she considered me a seizure risk (I wasn't, to be clear...) then another insurance issue.... I've finally been with one long enough to go to every three months for appointments. I saw the same woman for seven years in my early twenties and I despised her, but that continuity of care was nice, looking back.

I'm now on nal, sema, AND cagri. I'm doing pretty damn great, but I can't tell you which of the three to attribute that to. Drinking also stops my weight loss progress, so having a concrete goal and consequences is helping. Drinking = sema no workie = no drinkie for ChMuse. From what I've seen sema seems best for those addictive behaviors (I've actually cut down on Reddit and TikTok by miles, I've read four books so far in January.)

Isn’t it exciting the possibilities we are seeing with the GLP1s and mental health?! Do you feel Sema has a stronger impulse control effect than Tirz?

Oh yeah, the challenges with bipolar are compounded when we are on an SSRI/ SNRI/ NDRI and then get mood shifts in mania/ hypo/ depression. It’s can be hard to distinguish what’s an actual bipolar symptom vs. medication exacerbating the mental state. And then there’s digging through (possible) childhood trauma trying to unravel how strongly that’s linked to bipolar. I wish we could all get regular brain scans while we are undergoing treatments

 

[chmuse]

Isn’t it exciting the possibilities we are seeing with the GLP1s and mental health?! Do you feel Sema has a stronger impulse control effect than Tirz?

Oh yeah, the challenges with bipolar are compounded when we are on an SSRI/ SNRI/ NDRI and then get mood shifts in mania/ hypo/ depression. It’s can be hard to distinguish what’s an actual bipolar symptom vs. medication exacerbating the mental state. And then there’s digging through (possible) childhood trauma trying to unravel how strongly that’s linked to bipolar. I wish we could all get regular brain scans while we are undergoing treatments

Bipolar has been linked to blood glucose! Increased risk of type 1 and 2 diabetes, and iirc a link was found with 1.5 recently too. So a glp-1 helping makes a ton of sense to me- especially as keto had mine so well controlled until I couldn't maintain such a strict diet. No opinion on tirz, I haven't tried it yet. Sema had an immediate effect for me- within hours of the first dose, it was like a button in my brain had been pressed. Magic. I've only done sema and one dose of cagri so far (second dose tonight.) And parsing through everything is so incredibly difficult, sooooo many possible and common comorbidities, and environmental factors, etc etc.