how would we know that? i'm not disagreeing, but i'm just not sure how to know beyond guessing.
Amopure stinging (here we go again)
- Thread starter Fonkymonky
- Start date
If I understand what I'm reading, it says something about the solution matching with the body fluids. Could that mean that people will reach differently, depending on how closely the solution matches the body fluids? Meaning, everybody's different?
There's a lot of companies selling peptides. Amopure isn't doing anything new or unique.
And, this patent is from 1996. Has this stuff been around for almost 30 years?
their barrier to entry seems rather... unique? how many vendors have a website, offer 60mg kits and offer paypal/applepay/googlepay/klarna etc with quick shipping? i'm sure it's not a very long list, at least specific to tirz.
Never heard of tonicity. Again, I wonder if this is the reason for the stinging sometimes reported?
Tonicity is a measure of how a solution affects the volume of cells by changing their water content. It's determined by whether a solution is hypotonic, isotonic, or hypertonic:
- Hypotonic: Cells swell due to water entering the cell
- Isotonic: Cells do not change volume because there is a balance of water inside and outside the cell
- Hypertonic: Cells shrink due to water leaving the cell
It might not be a matter of Amo changing their formulation. Could it be differences in individuals?
Tonicity is a measure of how a solution affects the volume of cells by changing their water content. It's determined by whether a solution is hypotonic, isotonic, or hypertonic:
- Hypotonic: Cells swell due to water entering the cell
- Isotonic: Cells do not change volume because there is a balance of water inside and outside the cell
- Hypertonic: Cells shrink due to water leaving the cell
That seems like the date of the journal they're quoting. I see the patent from 2019. (But it wouldn't surprise me if they knew about it for 30 years and never told us too
)Could this explain the stinging you experience?
Tonicity is a measure of how a solution affects the volume of cells by changing their water content. It's determined by whether a solution is hypotonic, isotonic, or hypertonic:
- Hypotonic: Cells swell due to water entering the cell
- Isotonic: Cells do not change volume because there is a balance of water inside and outside the cell
- Hypertonic: Cells shrink due to water leaving the cell
I'm curious about the change from powder to a hard puck. If that's caused by jiggling around during shipping that causes the powder to pack down, that can't be good, can it? I ask because the instructions for reconstituting say not to shake the solution but to roll it gently or let it sit and dissolve. The product is too fragile to withstand shaking the vial.
I'm still using the tirz I got from a compounding pharmacy before the FDA situation. These are my reactions from the same vial, the same type of syringes, same person.
1. Didn't feel a thing. No needle poke, no nothing.
2. Stung/hurt a little bit while injecting
3. Hurt and left a 2-week bruise at the injection site.
4. The poke pinched a little but not much
5. Hurt and left a 2-week bruise.
6. Nothing to report.
7. A little pinch
8. Didn't feel a thing
It seems like every week is different.
moonpies4misfits
Research Enthusiast
The puck is formed during the lyophilization process. From what I've seen talked about in other forums, some of these peps aren't quite as fragile as they're made out to be. If they can survive shipping halfway across the globe, I doubt a gentle shake during reconstitution would have a big impact.
I thought the recipe was 1 to 1. 1 ml bac to 10mg peptide. That's kind of 1 to 1.
20mg peptide, 2 ml bac.
30 mg peptide, 3 ml bac.
Is that right?
You can mix it any way you like. Some people use less bac to take smaller doses. I add 1.2ml water to 30mg
Please note, the dosage on this calculator is in mcg.
MakeItaDouble
New_Member
I started on my 60mg Amo tirz that was part of the big August buy/group test. Reconstituted with 1.2 ml Bac. No stinging, no ISR.
Thanks for this!
maliaharris
Registered
I’ve been using AMO Tirz 30 since Aug 28. So far, so good.Perfect product,fits exactly as expected.
Injected RS about an hour ago with the vial that gelled during reconstitution. Went up to 10mg dose this week.
Zero burning/stinging reported, everything was normal just like with the previous vial. Will report back in a day or two if there are any updates.
I was lazy and didnt backfill another syringe today, and damn that stopper blunts the needle lol literally my only complaint at this point with amo
edit: just to note, I reconstituted this vial 3-4 days ago. A small portion stuck to the side, a gelish substance that took a few extra minutes to reconstitute. There is a picture a few pages back where I discussed this. I'm not injecting my rs with gel lmao
Zero burning/stinging reported, everything was normal just like with the previous vial. Will report back in a day or two if there are any updates.
I was lazy and didnt backfill another syringe today, and damn that stopper blunts the needle lol literally my only complaint at this point with amo
edit: just to note, I reconstituted this vial 3-4 days ago. A small portion stuck to the side, a gelish substance that took a few extra minutes to reconstitute. There is a picture a few pages back where I discussed this. I'm not injecting my rs with gel lmao
Last edited:
You injected one that gelled? Did it un-gel before you made it part of your body?
