I'm curious about the change from powder to a hard puck. If that's caused by jiggling around during shipping that causes the powder to pack down, that can't be good, can it? I ask because the instructions for reconstituting say not to shake the solution but to roll it gently or let it sit and dissolve. The product is too fragile to withstand shaking the vial.
Amopure stinging (here we go again)
- Thread starter Fonkymonky
- Start date
I'm still using the tirz I got from a compounding pharmacy before the FDA situation. These are my reactions from the same vial, the same type of syringes, same person.
1. Didn't feel a thing. No needle poke, no nothing.
2. Stung/hurt a little bit while injecting
3. Hurt and left a 2-week bruise at the injection site.
4. The poke pinched a little but not much
5. Hurt and left a 2-week bruise.
6. Nothing to report.
7. A little pinch
8. Didn't feel a thing
It seems like every week is different.
moonpies4misfits
Research Enthusiast
The puck is formed during the lyophilization process. From what I've seen talked about in other forums, some of these peps aren't quite as fragile as they're made out to be. If they can survive shipping halfway across the globe, I doubt a gentle shake during reconstitution would have a big impact.
I thought the recipe was 1 to 1. 1 ml bac to 10mg peptide. That's kind of 1 to 1.
20mg peptide, 2 ml bac.
30 mg peptide, 3 ml bac.
Is that right?
You can mix it any way you like. Some people use less bac to take smaller doses. I add 1.2ml water to 30mg
Please note, the dosage on this calculator is in mcg.
MakeItaDouble
New_Member
I started on my 60mg Amo tirz that was part of the big August buy/group test. Reconstituted with 1.2 ml Bac. No stinging, no ISR.
Thanks for this!
maliaharris
Registered
I’ve been using AMO Tirz 30 since Aug 28. So far, so good.Perfect product,fits exactly as expected.
Injected RS about an hour ago with the vial that gelled during reconstitution. Went up to 10mg dose this week.
Zero burning/stinging reported, everything was normal just like with the previous vial. Will report back in a day or two if there are any updates.
I was lazy and didnt backfill another syringe today, and damn that stopper blunts the needle lol literally my only complaint at this point with amo
edit: just to note, I reconstituted this vial 3-4 days ago. A small portion stuck to the side, a gelish substance that took a few extra minutes to reconstitute. There is a picture a few pages back where I discussed this. I'm not injecting my rs with gel lmao
Zero burning/stinging reported, everything was normal just like with the previous vial. Will report back in a day or two if there are any updates.
I was lazy and didnt backfill another syringe today, and damn that stopper blunts the needle lol literally my only complaint at this point with amo
edit: just to note, I reconstituted this vial 3-4 days ago. A small portion stuck to the side, a gelish substance that took a few extra minutes to reconstitute. There is a picture a few pages back where I discussed this. I'm not injecting my rs with gel lmao
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You injected one that gelled? Did it un-gel before you made it part of your body?
Vacation4us
Registered
Not the best resealing vial either. I did use an 18 g needle with my BAC but I lost an entire 15 mg dose to dripping out the vial while drawing up the 3 other doses out of my T 60. Hope that doesn’t happen when I use a 25 g to reconstitute in 2 weeks. That would be 10 weeks of lost doses if it keeps happening.
Of course haha - was updating a previous post. I reconstituted it a few days prior, and a small portion gelled up on the side and took a few extra minutes to fully dissolve. If you go a few pages back I included a pic.
I use whatever amount makes the math easy when drawing out.
I am currently dosing at 10mg, so my 30mg vial gets .90 ml of Bacc water so each draw is 30 units.
I have 60mg vials on order and will probably move up to 12mg dose when they arrive, so will add 1.25 ml bacc for a 25 unit draw.
Vacation4us
Registered
I don’t know if they are “cheaping out” on the vials. Vials leaking is not an unusual situation even with hospital vials I have used.If they are cheaping out on the vial tops what else are they cheaping out on?
Pr0digalSun
New_Member
Hi I joined this forum bc I found this thread when I googled “amopure tirz burning” and tbh I skipped pages 4-14 of the thread.
I can absolutely confirm this has nothing to do with needles dulling on stoppers, bc I use 1cc luer lock syringes with a preattached 25g to draw, then switch to a 31ga, just out of habit bc I do testosterone and HCG subQ injections EOD
RS has been on injectables almost all of the last 20 years, and out of any injection that they have ever done, including deep IM with fat 20ga needles, and trimix injections into their d*ck, the amo tirz was the most painful injection of RS’s life. Like shockingly painful. Hot burning lava during injection then lingering burn for 30 minutes.
Changing from 1/2” to 3/16” needle length, and changing from abdomen to thigh does not change the amount of burn. This is L15 diluted with 1ml bac water.
The product, however, is very effective. The vendor offered to replace with a different batch and responded within minutes of my email.
I suspect it’s related to an excipient like sodium citrate or another added preservative (but I’m just guessing). I can update here if the replacement product hurts as bad.
The most comfortable way found to inject is using 1/2” needle into a pinch of folded skin injected relatively slowly.
I can absolutely confirm this has nothing to do with needles dulling on stoppers, bc I use 1cc luer lock syringes with a preattached 25g to draw, then switch to a 31ga, just out of habit bc I do testosterone and HCG subQ injections EOD
RS has been on injectables almost all of the last 20 years, and out of any injection that they have ever done, including deep IM with fat 20ga needles, and trimix injections into their d*ck, the amo tirz was the most painful injection of RS’s life. Like shockingly painful. Hot burning lava during injection then lingering burn for 30 minutes.
Changing from 1/2” to 3/16” needle length, and changing from abdomen to thigh does not change the amount of burn. This is L15 diluted with 1ml bac water.
The product, however, is very effective. The vendor offered to replace with a different batch and responded within minutes of my email.
I suspect it’s related to an excipient like sodium citrate or another added preservative (but I’m just guessing). I can update here if the replacement product hurts as bad.
The most comfortable way found to inject is using 1/2” needle into a pinch of folded skin injected relatively slowly.
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Pr0digalSun
New_Member
Also I wanted to add that peptides are two amino acids linked in a chain, and I don’t know who started the myth, but shaking peptides does not break their molecular structure.
Ozempic and Mounjaro are predisolved in pens and there aren’t warnings on the boxes not to drop.
My degree is in chemistry and imho there are probably three things that could cause the burning
1. Incomplete synthesis leaving unreacted precursors
2. Excipients added as preservatives (like sodium citrate) or to ph balance (like HCl or NaOH)
3. Incomplete solubility caused by clumping
Since they pass their purity tests and since I know they are effective IMHO it’s bc the powder isn’t completely dissolving, and this would kind of track with why it seems I see small inconsistencies in the viscosity in the vial after mixing.
Ozempic and Mounjaro are predisolved in pens and there aren’t warnings on the boxes not to drop.
My degree is in chemistry and imho there are probably three things that could cause the burning
1. Incomplete synthesis leaving unreacted precursors
2. Excipients added as preservatives (like sodium citrate) or to ph balance (like HCl or NaOH)
3. Incomplete solubility caused by clumping
Since they pass their purity tests and since I know they are effective IMHO it’s bc the powder isn’t completely dissolving, and this would kind of track with why it seems I see small inconsistencies in the viscosity in the vial after mixing.
Pr0digalSun
New_Member
Don’t get me wrong, im probably gonna grit my teeth and keep using unless it starts leaving lasting or visible reactions
