It was on a private discord so it can’t be linked. You can ask him about it though if you’re on any forums where he participates.
Nexaph testing
- Thread starter DwightTheDelight
- Start date
Are you talking specifically about the mannitol in the Retatrutide? Or something else?
zpped
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Mannitol is a standard excipient in glp1s. I'm talking about histidine
and as ewb said, jano said its a bad idea, it can hide impurities and interacts with glp1 in unpredictable ways.
noteablequotable
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Look, Cain and I are not friends. I am an occasional customer who understands their background, and I continue to do business with them because I find the additional scrutiny they receive beneficial from a risk perspective. Whether or not you realize it this community has more leverage over Nexaph then we will EVER have over any other vendor specifically because their past behavior and that's very useful when it comes to extracting concessions on certain issues. I've intentionally shined a spotlight on him in the past to ensure forum members get the best possible outcomes for them (better than they'd get from any other vendor) and I like that dynamic a lot.
However, that only works because I'm precise in my criticism of them and I don't ask questions about their practices that I don't also ask about other vendors. It's clear that Cain used a different excipient than Janoshik expected with that batch of Tirz, but we have no evidence that it poses a risk to the health and safety of his customers, or might cause the Tirz to degrade more rapidly. We also don't know (and haven't asked) about the excipients other companies use. Maybe they use the same ones as Lilly, but maybe they don't. Maybe everyone is using different excipients based on what makes the most financial sense for them.
We know that AmoPure changed their excipients at least twice, and according to them the first change resulted in an increase in serious ISRs. There was certainly some talk about that, but no one put up any warnings about them. When I tried to get people to investigate those efforts fell flat. That was an obvious and immediate health and safety concern that was clearly related to the company's formulation (again, they admitted as much), and it never garnered this much suspicion or concern.
Can you share that information? I never saw Janoshik say anything about the excipient interacting with the GLP-1 in an unusual way. THAT would be very important and would definitely warrant investigation.
That's not why people continue to use Nexaph. People choose Nexaph because he meets their standards for quality, safety and convenience. I've never seen a test results below 98%, always reasonable fill, his products don't give weird ISRs or unexpected sides, and his customer service is closer to ASC than QSC, everything else is a bonus. Until one of the above changes, people will continue to buy from him.
zpped
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Amo also 1)told us it was happening, 2) was criticized to all hell for the ISRs, 3) They aren't actually well regarded around here anymore. I put them a hair higher than nexaph, mostly because of longevity.
Jano's comment is in the testing group. If you're a member I can show you exactly where. But that is a word for word quote. He didn't say much else other than he recommended him not use it, and it can hide other impurities.
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noteablequotable
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I am not in the testing group so I wasn't aware of this. I can understand why groups like that are invite only, but one of the downsides is that critical information like this doesn't circulate as far as it should. I have a lot of questions for Cain including:
1. What he was using before, and why he decided to switch to this excipient
2. What he did in response to Jano's feedback.
3. Whether or not customers received products made with this excipient, and if he's still using it.
Did he answer any of that?
zpped
Registered
Cain isn't allowed there, but I'm sure he knows it was said. It was jano telling us about it. You'd have to ask Cain, I believe he's spoken about it at some point. Personally I wrote him off as an potential option last time so I'm not seeking out his side. (he also got in trouble over at tirzhelp for another thing recently too)
The downside of not being in the deeper end is it takes longer for information to float up here. But we really do try to keep people informed. If you care about verifying stuff like that and seeing it for yourself I'm happy to help you get in.
