Nexaph testing

[husla22]

they caught several sub-99 tests though, which seems to conflict with the “alls well this is just in case” story

I'm not getting into an argument with you, but in my experience, they have one of the highest levels of transparency. What I ordered had a very high purity and I am going to send for endotoxin screening and sterility soon but they have posted sterility reports from other users that have passed. I'm talking proper USP 71 sterility and not Janoshik sterility.

They had a test result for something come out below 99% on one vial (out of three tested) and sent out replacements for free for everyone that ordered it and people could keep the original vials.

While I'm sure you can find individuals who had a bad experience with them, we have to look at things holistically and this company seems to be very transparent with a high % of repeat customers.

 

[clevesand]

I think the alarming thing with Nexaph is they're the only ones having this issue right now, and we've all pretty much figured out this stuff comes for 2 or 3 major players in China. So here is this company coming onto the market with something that is not in line with what everyone else is seeing. To me this means they're using a channel that is different--and frankly not very good. Coincidentally, it also comes at a time where we are seeing record low prices. This makes me think there is a disruptor in China up to some shit. Lowering prices, and not as good. I think the best time to buy was a couple of months ago. Anyone in the market right now my best advice is to wait and see a little bit. But do your thing.

 

[Blimey]

I think the alarming thing with Nexaph is they're the only ones having this issue right now, and we've all pretty much figured out this stuff comes for 2 or 3 major players in China. So here is this company coming onto the market with something that is not in line with what everyone else is seeing. To me this means they're using a channel that is different--and frankly not very good. Coincidentally, it also comes at a time where we are seeing record low prices. This makes me think there is a disruptor in China up to some shit. Lowering prices, and not as good. I think the best time to buy was a couple of months ago. Anyone in the market right now my best advice is to wait and see a little bit. But do your thing.

They tried a different filler or whatever it’s called, one batch. They reshipped for everyone who ordered that batch. Everyone has their own opinion and risk threshold but 98% seems great to me.

The nice thing is we have multiple options for sources so everyone can do business with who they are comfortable with.

 

[zpped]

in my experience, they have one of the highest levels of transparency.

I'm curious how much experience that is? Because this is a VERY funny statement.

They tried a different filler or whatever it’s called, one batch.

Do you not see how insanely dangerous that is? They are experimenting on you without even telling you.

 

[noteablequotable]

Do you not see how insanely dangerous that is? They are experimenting on you without even telling you.

I know you're not a fan but this is a little much. Manufacturers do not consult us about the fillers they use, we don't ask about them, and there is no evidence that the new filler is dangerous (Janoshik recognized it). Unless we start asking everyone about their fillers as standard practice this is not something to get upset about.

 

[peptideusername]

I know you're not a fan but this is a little much. Manufacturers do not consult us about the fillers they use, we don't ask about them, and there is no evidence that the new filler is dangerous (Janoshik recognized it). Unless we start asking everyone about their fillers as standard practice this is not something to get upset about.

I think this should be a regular question to ask. Why not? It used to just be mannitol, but now we have a reason to ask!

 

[penewbie]

Do you not see how insanely dangerous that is? They are experimenting on you without even telling you.

INSANELY dangerous?

Do you think they're using cyanide as filler?

 

[zpped]

I know you're not a fan but this is a little much. Manufacturers do not consult us about the fillers they use, we don't ask about them, and there is no evidence that the new filler is dangerous (Janoshik recognized it). Unless we start asking everyone about their fillers as standard practice this is not something to get upset about.

I didn't say the filler was dangerous. I said experimenting and not telling people about it is dangerous. The fact this is a controversial statement is mind boggling.

Of course we should hold every vendor to the same standard. Let me know which other one has been caught tinkering with the formula and hasn't been dragged for it?

 

[noteablequotable]

I think this should be a regular question to ask. Why not? It used to just be mannitol, but now we have a reason to ask!

That's fine by me then, as long as we aren't setting different standards for different people.

 

[noteablequotable]

I didn't say the filler was dangerous. I said experimenting and not telling people about it is dangerous. The fact this is a controversial statement is mind boggling.

Of course we should hold every vendor to the same standard. Let me know which other one has been caught tinkering with the formula and hasn't been dragged for it?

I don't think it's fair to call it an "experiment" if it's a known excipient though. Imho using a different filler isn't tinkering with the formula as long as the active ingredients (Tirzepatide, Retatrutide, etc.) doesn't change, and it's a a known, safe, excipient that doesn't pose a risk to human health.

I can't recall the name off the top of my head but I don't believe any of those things are an issue with the excipient he chose, so unless we want to start demanding manufacturers only use specific excipients there's nothing to be upset about.

 

[zpped]

I don't think it's fair to call it an "experiment" if it's a known excipient though. Imho using a different filler isn't tinkering with the formula as long as the active ingredients (Tirzepatide, Retatrutide, etc.) doesn't change, and it's a a known, safe, excipient that doesn't pose a risk to human health.

I can't recall the name off the top of my head but I don't believe any of those things are an issue with the excipient he chose, so unless we want to start demanding manufacturers only use specific excipients there's nothing to be upset about.

The fact is he changed the ingredients to something completely novel in tirz without telling his customers. You, I, Jano, Cain, and everyone else doesn't actually know the effects of using that ingredient with tirz. Calling it an experiment is generous.

We absolutely should hold every vendor to the same standard, I don't think anyone has said otherwise and its weird you keep repeating it.

 

[Bbnp1]

Its not changing an ingredient of the main peptide, every manufacturer is using excipients to prevent degradation and those excipients are well known

 

[zpped]

Its not changing an ingredient of the main peptide

ingredient in the vial of tirz... aka excipients. I'm very aware of exactly what happened.

every manufacturer is using excipients to prevent degradation and those excipients are well known

Who said they didn't? Yes they are well known and fairly standard. This specific excipient isn't well known in this use case because no one has used it with glp1s before. which is why Jano called it out.

 

[exploitedworkerbee]

Its not changing an ingredient of the main peptide, every manufacturer is using excipients to prevent degradation and those excipients are well known

Janoshik said this filler was interacting with glp1s in unusual ways. So sure, it’s used in other meds, but not glp1s. Nexaph totally shit the bed on this one and it’s indefensible but he takes PayPal so a bunch of people stick their heads in the sand.

Mind you this is a company that has existed for what, 4 months? These guys have a truly heinous track record but again, that sweet sweet PayPal and giveaway marketing gimmicks on newbie forums makes everyone blind to that fact, transforming baba into some sort of community servant. Its quite a thing to behold.

 

[penewbie]

Janoshik said this filler was interacting with glp1s in unusual ways. So sure, it’s used in other meds, but not glp1s.

Oh this is the first I'm hearing of this (and from the comment above). I'm intrested in learning more, anyone have the link to what Jano said?

 

[exploitedworkerbee]

Oh this is the first I'm hearing of this (and from the comment above). I'm intrested in learning more, anyone have the link to what Jano said?

It was on a private discord so it can’t be linked. You can ask him about it though if you’re on any forums where he participates.

 

[beefsteak]

I reconstituted 30mg nexaph recently with 3ml hosperia bac and it clogged the 4mm filter before I was able to get all of the contents out. Not sure of what kind of fillers they used.

 

[Bbnp1]

ingredient in the vial of tirz... aka excipients. I'm very aware of exactly what happened.


Who said they didn't? Yes they are well known and fairly standard. This specific excipient isn't well known in this use case because no one has used it with glp1s before. which is why Jano called it out.

Are you talking specifically about the mannitol in the Retatrutide? Or something else?

 

[zpped]

Are you talking specifically about the mannitol in the Retatrutide? Or something else?

Mannitol is a standard excipient in glp1s. I'm talking about histidine

and as ewb said, jano said its a bad idea, it can hide impurities and interacts with glp1 in unpredictable ways.

 

[noteablequotable]

We absolutely should hold every vendor to the same standard, I don't think anyone has said otherwise and its weird you keep repeating it.

Look, Cain and I are not friends. I am an occasional customer who understands their background, and I continue to do business with them because I find the additional scrutiny they receive beneficial from a risk perspective. Whether or not you realize it this community has more leverage over Nexaph then we will EVER have over any other vendor specifically because their past behavior and that's very useful when it comes to extracting concessions on certain issues. I've intentionally shined a spotlight on him in the past to ensure forum members get the best possible outcomes for them (better than they'd get from any other vendor) and I like that dynamic a lot.

However, that only works because I'm precise in my criticism of them and I don't ask questions about their practices that I don't also ask about other vendors. It's clear that Cain used a different excipient than Janoshik expected with that batch of Tirz, but we have no evidence that it poses a risk to the health and safety of his customers, or might cause the Tirz to degrade more rapidly. We also don't know (and haven't asked) about the excipients other companies use. Maybe they use the same ones as Lilly, but maybe they don't. Maybe everyone is using different excipients based on what makes the most financial sense for them.

You, I, Jano, Cain, and everyone else doesn't actually know the effects of using that ingredient with tirz. Calling it an experiment is generous.

We know that AmoPure changed their excipients at least twice, and according to them the first change resulted in an increase in serious ISRs. There was certainly some talk about that, but no one put up any warnings about them. When I tried to get people to investigate those efforts fell flat. That was an obvious and immediate health and safety concern that was clearly related to the company's formulation (again, they admitted as much), and it never garnered this much suspicion or concern.

Janoshik said this filler was interacting with glp1s in unusual ways.

Can you share that information? I never saw Janoshik say anything about the excipient interacting with the GLP-1 in an unusual way. THAT would be very important and would definitely warrant investigation.

Nexaph totally shit the bed on this one and it’s indefensible but he takes PayPal so a bunch of people stick their heads in the sand.

That's not why people continue to use Nexaph. People choose Nexaph because he meets their standards for quality, safety and convenience. I've never seen a test results below 98%, always reasonable fill, his products don't give weird ISRs or unexpected sides, and his customer service is closer to ASC than QSC, everything else is a bonus. Until one of the above changes, people will continue to buy from him.

 

[zpped]

We know that AmoPure changed their excipients at least twice..

Can you share that information? I never saw Janoshik say anything about the excipient interacting with the GLP-1 in an unusual way. THAT would be very important and would definitely warrant investigation.

Amo also 1)told us it was happening, 2) was criticized to all hell for the ISRs, 3) They aren't actually well regarded around here anymore. I put them a hair higher than nexaph, mostly because of longevity.

Jano's comment is in the testing group. If you're a member I can show you exactly where. But that is a word for word quote. He didn't say much else other than he recommended him not use it, and it can hide other impurities.

 

[noteablequotable]

Jano's comment is in the testing group. If you're a member I can show you exactly where. But that is a word for word quote. He didn't say much else other than he recommended him not use it, and it can hide other impurities.

I am not in the testing group so I wasn't aware of this. I can understand why groups like that are invite only, but one of the downsides is that critical information like this doesn't circulate as far as it should. I have a lot of questions for Cain including:

1. What he was using before, and why he decided to switch to this excipient
2. What he did in response to Jano's feedback.
3. Whether or not customers received products made with this excipient, and if he's still using it.

Did he answer any of that?

 

[zpped]

I am not in the testing group so I wasn't aware of this. I can understand why groups like that are invite only, but one of the downsides is that critical information like this doesn't circulate as far as it should. I have a lot of questions for Cain including:

1. What he was using before, and why he decided to switch to this excipient
2. What he did in response to Jano's feedback.
3. Whether or not customers received products made with this excipient, and if he's still using it.

Did he answer any of that?

Cain isn't allowed there, but I'm sure he knows it was said. It was jano telling us about it. You'd have to ask Cain, I believe he's spoken about it at some point. Personally I wrote him off as an potential option last time so I'm not seeking out his side. (he also got in trouble over at tirzhelp for another thing recently too)

The downside of not being in the deeper end is it takes longer for information to float up here. But we really do try to keep people informed. If you care about verifying stuff like that and seeing it for yourself I'm happy to help you get in.

 

[noteablequotable]

Cain isn't allowed there, but I'm sure he knows it was said. It was jano telling us about it. You'd have to ask Cain, I believe he's spoken about it at some point. Personally I wrote him off as an potential option last time so I'm not seeking out his side. (he also got in trouble over at tirzhelp for another thing recently too)

The downside of not being in the deeper end is it takes longer for information to float up here. But we really do try to keep people informed. If you care about verifying stuff like that and seeing it for yourself I'm happy to help you get in.

I appreciate the offer. I am ready trying to connect with someone in discord so that they can invite me to the test group, but I'll let you know if that doesn't work out.

 

[exploitedworkerbee]

I am not in the testing group so I wasn't aware of this. I can understand why groups like that are invite only, but one of the downsides is that critical information like this doesn't circulate as far as it should. I have a lot of questions for Cain including:

1. What he was using before, and why he decided to switch to this excipient
2. What he did in response to Jano's feedback.
3. Whether or not customers received products made with this excipient, and if he's still using it.

Did he answer any of that?

I can tell you the answer to #3 is yes. It was at least retatrutide, possibly other peptides but the reta is all i am certain about. i know this because baba was saying he'd do some work with jano to investigate the low purity and then reship if it didnt pan out. I asked jano about this later to see what came of it, which is the discord convo @zpped referenced. Jano said it interacted with GLP1s in unusual ways and seemed like he didnt think it was a good move to go sending that to people to use. What actions baba took after this I don't know, he has been unsurprisingly silent on the matter, probably tried to sweep it under the rug along with all the other unimpressive testing his customers keep churning out.

BUT HE TAKES CREDIT CARD!!!!!! Let's keep our priorities straight here!!!!

I’ll check w the admins at the testing server to see if they’re ok w me posting screen shots of the convo

 

[GimmeABreak]

I can tell you the answer to #3 is yes. It was at least retatrutide, possibly other peptides but the reta is all i am certain about. i know this because baba was saying he'd do some work with jano to investigate the low purity and then reship if it didnt pan out. I asked jano about this later to see what came of it, which is the discord convo @zpped referenced. Jano said it interacted with GLP1s in unusual ways and seemed like he didnt think it was a good move to go sending that to people to use. What actions baba took after this I don't know, he has been unsurprisingly silent on the matter, probably tried to sweep it under the rug along with all the other unimpressive testing he keeps churning out.

I am part of a retest group on TG and contributed to the testing cost. There is a women running it that I think is a biologist and works in a lab that has the equipment to test much more than purity/mass. I don't completely understand all of the tests that she is running but we needed a dozen donor vials and the cost (with her discount) was $750. She is trying to identify the excipient used, if the reta will degrade faster than "normal" and if the product is safe to use. We should have results in the next week or so but given the tests I think we will need her interpratation of the results.

 

[Vicki]

I know you're not a fan but this is a little much. Manufacturers do not consult us about the fillers they use, we don't ask about them, and there is no evidence that the new filler is dangerous (Janoshik recognized it). Unless we start asking everyone about their fillers as standard practice this is not something to get upset about.

Just for clarity. His follow up test said histidine was not detected. So I'm not aware that he recognized what was in it.

 

[chmuse]

Ach, deleted just as I click the links! How am I supposed to stop saying Nexa is good to noobs if the screenshots are deleted before I can be nosy! (Mostly kidding)

 

[exploitedworkerbee]

@noteablequotable

Here is the discussion we talked about. I had to slice and dice it a little because there were multiple convos happening simultaneously and the relevant bit is between me and jano. Note that the guy who talks about heat resistance works with baba.

 

[exploitedworkerbee]

Ach, deleted just as I click the links! How am I supposed to stop saying Nexa is good to noobs if the screenshots are deleted before I can be nosy! (Mostly kidding)

i messed up the redactions so had to delete and repost. your screenshots are there for ya now 🙂