SS-31 + MOTs-C vs NAD+

[Desieldogg]

I'm looking to battle some fatigue, and I've read endlessly about SS-31/MOTs-C/NAD+, but I'm still having trouble deciding how I should proceed. Should I start with the SS/MOT protocol, then move to NAD+? After SS, do I stay on MOT forever?

 

[Loeve]

They're synergistic. Prime with SS-31 to repair mitochondria and then stack MOTS-C and NAD+.

 

[randompersonrandom]

I'm glad this protocol is getting super popular all at once; it'll be cool in four months when a whole bunch of us are either like "YOU GUYS I HAVE SO MUCH ENERGY SO HAPPY" together, or "DIDN'T DO SHIT FOR ME" all together.

 

[Loeve]

I'm glad this protocol is getting super popular all at once; it'll be cool in four months when a whole bunch of us are either like "YOU GUYS I HAVE SO MUCH ENERGY SO HAPPY" together, or "DIDN'T DO SHIT FOR ME" all together.

Did you make it or did it originate here? I just had the PDF shared with me.

 

[randompersonrandom]

Did you make it or did it originate here? I just had the PDF shared with me.

no, I don't know where it originated; only that it's been posted here a lot lately.

 

[Such1943]

I'm glad this protocol is getting super popular all at once; it'll be cool in four months when a whole bunch of us are either like "YOU GUYS I HAVE SO MUCH ENERGY SO HAPPY" together, or "DIDN'T DO SHIT FOR ME" all together.

I’m all for it. I’m starting the protocol most likely in December.

 

[Doug5421]

The protocol spinning around seems cool in theory, but imo, think the most benefit will come from indefinite NR/NMN supplementation w/ periodic cycles of SS-31 due to repair and upkeep. MOTS-C, possibly for performance enhancement. Just my 2 cents.

 

[Twowheelr2]

They're synergistic. Prime with SS-31 to repair mitochondria and then stack MOTS-C and NAD+.

This is a 14 Week protocol. Weeks 13 and 14 are the same as Week 12..MOTS-c and NADS+. The PDF has links to files and research documentation to explain the reasoning behind this schedule. I started it Firday.

 

[Twowheelr2]

View: https://youtu.be/MPMJLA38o8M?si=HqZrRzuXPIUedmsN

 

[PAPoots]

So what kind of feeling should I expect from NAD+. I'm in my 3rd week and have titrated up to 50mg and pin M,W, F first thing in the morning. This is v30 units when 500mg vial is reconstituted with 3ml. I also take 500mcg of Semax daily SubQ.

No feelings yet. I'm about 8 weeks away from kicking in the MOTS-c protocol. I'll also have finished a 20 day, 5mg in the evening Epitalon round in 3 more days.

The only thing that has happened is my sleep scores have dropped from the high 80s to 70s or lower.

Is this like a Tesa protocol where you gain water weight and lose visceral fat, and you don't see the results until sometime after the protocol is complete?

I was really hoping to feel a little more wakefulness in the am and having some better morning workouts.

 

[Chili777]

I've been on oral NR (300mg) for years and it's affect is subtle. It's not that I notice anything special when I'm taking it, it's that I do notice when I don't. If you got quality NAD, I would just trust that it's working. My 2 cents.

 

[Such1943]

I just started the protocol this week. I noticed some energy, hard to describe but I’ll call it clean, I guess. My coffee consumption was down from the Reta, but I did not even make a pot this week. My sleep app shows I fell asleep later and woke up earlier than usual Wed, Thurs and Fri. So far so good I would say. Placebo? I’ll report back next week. 45/M

	Monday	Tuesday	Wednesday	Thursday	Friday	Saturday	Sunday
Week 1 12/1	NAD+ 150mg SS-31 3mg	SS-31 3mg	NAD+ 150mg SS-31 3mg	SS-31 3mg	NAD+ 150mg SS-31 3mg	SS-31 3mg	SS-31 3mg

 

[badugib]

I want to start that 14 week protocol from that pdf file as well. Once my ss-31 and nad+ arrives. Has anyone followed that procedure? And what were your results?

 

[Jellybelly54]

Somewhere in there someone should work in 5A1MQ. Mix in that freaky orange stuff for added energy and increased NAD+ through the NNMT inhibition.

 

[PopTart]

I want to start that 14 week protocol from that pdf file as well. Once my ss-31 and nad+ arrives. Has anyone followed that procedure? And what were your results?

I’ve been doing the protocol for 6+ weeks - starting mots tomorrow. Going to pin mots on my gym days to see if it boosts performance. I don’t “feel” anything from NAD but that doesn’t mean that it’s not working. I get a huge energy and mental clarity boost from SS-31. I’m in my early 60s. I try to stick to OMAD most days to trigger mitophagy. It’s definitely a YMMV stack as some at my age experience a benefit while others don’t.

 

[Chili777]

I think you (and I) being in our 60s are exactly who this protocol is designed for and the studies linked in the doc bear that out. All three of these peptides diminish as we get older, so this is a way to replenish our mitochondrial factories. I read that the decline starts around 40. That's important because, as it was pointed out to me, these dosages are fairly high for someone under that age. Peptides, in my view, are for people trying recapture some of that vigor they used to have at 30, not for a 30 YO to become 10 again. You can't optimize an optimal system any further and 20-30's is when these levels peak. I would just caution that younger people take that into account when trying to replicate this protocol.

 

[tendency]

The protocol spinning around seems cool in theory, but imo, think the most benefit will come from indefinite NR/NMN supplementation w/ periodic cycles of SS-31 due to repair and upkeep. MOTS-C, possibly for performance enhancement. Just my 2 cents.

Personally, I didnt feel much taking 100mcg of NAD+ for several weeks.

I do, however, get a very nice energy and mood boost from taking 600mg NR daily.

 

[Nathanologist]

Personally, I didnt feel much taking 100mcg of NAD+ for several weeks.

I do, however, get a very nice energy and mood boost from taking 600mg NR daily.

100mg, not 100mcg.