That sucks. I have been mixing my own KLOW (all separate vials from different vendors) and adding .5 ml epi/lido and absolutely no ISRs or burn. I did a premix vial from Eros of GLOW previously. I can say, two months in, besides my eyebrows growing bushier I cannot tell much of a skin difference. I will say my back, ankle and knees have not hurt....I gave up on glow. Too ouchy. Might try again when I can do the ratios myself, the one I had was leaving gigantic red painful welts. I looked like I was covered in mosquito bites.