GLP-1 Forum

Should I stack tirz and reta, or just use reta?

FatPanda

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Sep 20, 2025
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Houston, TX
I am on the first month of tirz, so 2.5 mgs, and only recently learned of reta. Would it make more sense to just do reta or to stack with tirz?
 
Stacking the two wouldn’t make much sense, they hit overlapping receptors, so you’d double up on side effects without added benefit. Better to ride Tirz through dose escalation and see how your body responds before even thinking about switching or combining.
 
I would stick with the tirz. for now and see how you respond over time. You can add reta. or switch over to it later if you stall out.This is an exiting time and if you pay attention to the details your results will be amazing. Keep it simple and use 1 at a time until you know how each effects you. Keep protein high and get your resistance training dialed in to preserve lean mass. Good luck on your journey, keep posting as you get results.
 
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